Hydroxypropyl Methylcellulose (HPMC) leHydroxyethyl Cellulose (HEC) ke lihlahisoa tse tsoang ho cellulose, tse sebelisoang haholo indastering, meriana, litlolo le mafapha a mang. Phapang ea bona e kholo e bonahala ka sebopeho sa limolek'hule, litšoaneleho tsa solubility, masimo a kopo le likarolo tse ling.
1. Sebopeho sa limolek'hule
Hydroxypropyl Methylcellulose (HPMC)
HPMC ke motsoako o qhibilihang ka metsing o hlahisoang ka ho hlahisa lihlopha tsa methyl (-CH3) le hydroxypropyl (-CH2CHOHCH3) ka har'a ketane ea molek'hule ea cellulose. Ka ho khetheha, sebopeho sa limolek'hule tsa HPMC se na le likarolo tse peli tse sebetsang, methyl (-OCH3) le hydroxypropyl (-OCH2CH(OH)CH3). Hangata, karo-karolelano ea selelekela ea methyl e phahame, athe hydroxypropyl e ka ntlafatsa ka nepo ho qhibiliha ha selulose.
Hydroxyethyl Cellulose (HEC)
HEC ke motsoako o hlahisoang ka ho hlahisa lihlopha tsa ethyl (-CH2CH2OH) ka har'a ketane ea molek'hule ea cellulose. Ka sebopeho sa hydroxyethyl cellulose, sehlopha se le seng kapa tse ngata tsa hydroxyl (-OH) tsa selulose li nkeloa sebaka ke lihlopha tsa ethyl hydroxyl (-CH2CH2OH). Ho fapana le HPMC, sebopeho sa limolek'hule tsa HEC se na le sebaka se le seng feela sa hydroxyethyl mme ha se na lihlopha tsa methyl.
2. Ho qhibiliha ha metsi
Ka lebaka la liphapang tsa sebopeho, ho qhibiliha ha metsi ha HPMC le HEC ho fapane.
HPMC: HPMC e na le ho qhibiliha ha metsi hantle, haholo-holo maemong a pH a sa nke lehlakore kapa a alkaline hanyenyane, ho qhibiliha ha eona ho molemo ho feta HEC. Kenyelletso ea lihlopha tsa methyl le hydroxypropyl e ntlafatsa ho qhibiliha ha eona hape e ka eketsa viscosity ea eona ka ho sebelisana le limolek'hule tsa metsi.
HEC: HEC e atisa ho qhibiliha ka metsing, empa ho qhibiliha ha eona ho batla ho fokola, haholo-holo metsing a batang, 'me hangata e hloka ho qhibiliha tlas'a maemo a futhumatsang kapa ho hloka likhahla tse phahameng ho finyella liphello tse tšoanang tsa viscosity. Ho qhibiliha ha eona ho amana le phapang ea sebopeho sa selulose le hydrophilicity ea sehlopha sa hydroxyethyl.
3. Viscosity le thepa ea rheological
HPMC: Ka lebaka la boteng ba lihlopha tse peli tse fapaneng tsa hydrophilic (methyl le hydroxypropyl) ka limolek'hule tsa eona, HPMC e na le thepa e ntle ea ho fetola viscosity ka metsing 'me e sebelisoa haholo ho li-adhesives, li-coatings, li-detergents, litokisetso tsa meriana le likarolo tse ling. Libakeng tse fapaneng, HPMC e ka fana ka phetoho ho tloha ho viscosity e tlase ho ea ho viscosity e phahameng, 'me viscosity e ela hloko liphetoho tsa pH.
HEC: The viscosity ea HEC e ka boela ea fetoloa ka ho fetola mahloriso, empa mefuta ea eona ea ho fetola viscosity e nyane ho feta ea HPMC. HEC e sebelisoa haholo-holo maemong ao ho oona ho hlokahalang viscosity e tlaase ho ea bohareng, haholo-holo kahong, li-detergents le lihlahisoa tsa tlhokomelo ea botho. Thepa ea rheological ea HEC e batla e tsitsitse, haholo-holo libakeng tse nang le acidic kapa tse sa jeleng paate, HEC e ka fana ka viscosity e tsitsitseng haholoanyane.
4. Libaka tsa kopo
Hydroxypropyl methylcellulose (HPMC)
Indasteri ea kaho: HPMC e atisa ho sebelisoa ka seretse sa samente le liphahlo ho indasteri ea kaho ho ntlafatsa metsi, ho sebetsa le ho thibela mapetsong.
Indasteri ea meriana: Joaloka moemeli oa ho laola ho lokolloa ha lithethefatsi, HPMC e sebelisoa haholo indastering ea meriana. E ke ke ea sebelisoa feela e le sesebelisoa sa ho etsa matlapa le li-capsules, empa hape e le sekhomaretsi ho thusa ho lokolloa ha lithethefatsi ka tsela e tšoanang.
Indasteri ea lijo: HPMC e atisa ho sebelisoa ho lokisa lijo e le stabilizer, thickener kapa emulsifier ho ntlafatsa sebopeho le tatso ea lijo.
Indasteri ea litlolo: E le setenya, HPMC e sebelisoa haholo lihlahisoa tse kang litlolo, li-shampoo, le li-conditioner ho eketsa viscosity le botsitso ba lihlahisoa.
Hydroxyethyl cellulose (HEC)
Indasteri ea kaho: HEC e atisa ho sebelisoa ka samente, gypsum, le li-adhesives tsa lithaele ho ntlafatsa metsi le nako ea ho boloka sehlahisoa.
Bahloekisi: HEC e atisa ho sebelisoa ho lihloekisi tsa malapa, li-detergents le lihlahisoa tse ling ho eketsa viscosity ea sehlahisoa le ho ntlafatsa phello ea ho hloekisa.
Indasteri ea litlolo: HEC e sebelisoa haholo lihlahisoa tsa tlhokomelo ea letlalo, li-gels tsa ho hlapa, li-shampoo, joalo-joalo e le moemeli o teteaneng le o emisang ho ntlafatsa sebopeho le botsitso ba sehlahisoa.
Ho ntšoa ha oli: HEC e ka boela ea sebelisoa ts'ebetsong ea ho ntša oli e le motenya ka har'a metsi a cheka metsi ho thusa ho eketsa viscosity ea mokelikeli le ho ntlafatsa phello ea ho phunya.
5. pH botsitso
HPMC: HPMC e tsotella haholo liphetoho tsa pH. Tlas'a maemo a acidic, solubility ea HPMC e fokotseha, e ka amang ts'ebetso ea eona. Ka hona, hangata e sebelisoa sebakeng se sa nke lehlakore ho isa tikolohong ea alkaline e nyane.
HEC: HEC e lula e tsitsitse ho feta mefuta e mengata ea pH. E na le matla a ho ikamahanya le maemo a acidic le alkaline, kahoo e atisa ho sebelisoa ha ho etsoa lihlahisoa tse hlokang botsitso bo matla.
HPMCleHECli fapane ka sebopeho sa limolek'hule, solubility, ts'ebetso ea tokiso ea viscosity, le libaka tsa ts'ebeliso. HPMC e na le ts'ebetso e ntle ea ho qhibiliha ha metsi le ts'ebetso ea tokiso ea viscosity, 'me e loketse lits'ebetso tse hlokang viscosity e phahameng kapa ts'ebetso e itseng e laoloang ea tokollo; ha HEC e na le botsitso bo botle ba pH le mefuta e mengata ea likopo, 'me e loketse liketsahalo tse hlokang viscosity e bohareng le e tlaase le ho ikamahanya le maemo a matla a tikoloho. Lits'ebetsong tsa sebele, khetho ea hore na ke boitsebiso bofe bo lokelang ho hlahlojoa ho latela litlhoko tse itseng.
Nako ea poso: Feb-24-2025