Boemo ba nts'etsopele ea theknoloji ea tlhahiso ea HPMC le ts'ebetso ea hydroxypropyl methyl cellulose Chaena

Boemo ba nts'etsopele ea theknoloji ea tlhahiso ea HPMC le ts'ebetso ea hydroxypropyl methyl cellulose Chaena

Hydroxypropyl methyl celluloseHPMCtlhahiso ea hona joale ea malapeng e fuoa pele ka theknoloji ea mokhoa oa mokelikeli, theknoloji ena e emeloa ke wuxi lik'hemik'hale tsa indasteri ea lipatlisiso le setsi sa moralo Chaena lilemong tsa bo-1970, katleho ea lipatlisiso motheong oa ho phahamisa, ea pele ke mokhoa oa khase ea etherification, hobane thepa ha e ikamahanye le naha ea rona, ebe e sebetsa ka mokhoa oa mokelikeli oa mokhoa oa etherification karabelo, Ho fihlela joale e ntse e le etherification e kholo ea mokhoa oa ho itlhatsoa o ntse o tsejoa. baetsi ba cellulose ether.

HPMC ea malapeng hydroxypropyl methyl cellulose tlhahiso ea ka kakaretso e sebelisa k'hothone e hloekisitsoeng e le lisebelisoa tse tala (baetsi ba bang le bona ba ile ba qala ho leka ho sebelisa makhasi a lehong), 'me grinder ea malapeng e sila kapa e sebelisa ka ho toba alkalization ea k'hothone e hloekisitsoeng, etherification e sebelisa mokelikeli o kopantsoeng oa binary, karabelo ho reactor e otlolohileng. Ts'ebetso ea tlhoekiso e sebelisa ts'ebetso ea nakoana eo mokelikeli oa tlhaho o tlosoang ka har'a mochini oa motlakase mme sehlahisoa se se nang mafura se hloekisoa ka lihlatsoa tse 'maloa le ho felloa ke metsi ka li-scrubbers le centrifuges. A qeta ho sebetsa sehlahiswa ka granulation intermittent, tlas'a futhumatsang boemo (ho na le boetse ho na le moetsi ntle le granulation), ho omisa le ho silakanya mokhoa o tloaelehileng, boholo ba tshebetso e khethehileng ke feela lieha hydration nako ea sehlahisoa (ka potlako qhala) sebetsa ntle le hlobo thibela le ho ajoa sebetsa, ambalaji sebelisa bukana tsela.

Mokhoa oa mohato oa mokelikeli o na le melemo e latelang: thepa ea ts'ebetso ea karabelo ea ka hare e nyenyane, litlhoko tsa matla a lisebelisoa li tlaase, kotsi e nyenyane; Ka mor'a ho emara ka lye,selulosee ka atolosoa ka botlalo 'me ka ho lekana alkaliized. Lye e na le ho kenella hantle le ho ruruha ha selulose. The etherification reactor e nyenyane, hammoho le ho ruruha junifomo ea selulose alkali, kahoo boleng ba sehlahisoa ke ho le bonolo ho laola, boemo ba sebaka le viscosity ka fumanoa ho feta junifomo dihlahiswa, mefuta e sa tsoaneng boetse ho le bonolo ho nka sebaka.

Leha ho le joalo, ts'ebetso ena e boetse e na le mefokolo e latelang: mochine o motlakase hangata ha o moholo haholo, mefokolo ea lipalo-palo e lebisa ho matla a fokolang a tlhahiso, e le ho ntlafatsa tlhahiso, ho hlokahala ho eketsa palo ea li-reactors; Lihlahisoa tse hloekisitsoeng le tse hloekisitsoeng li hloka lisebelisoa tse ngata, ts'ebetso e rarahaneng, matla a mosebetsi; Hobane ha ho na phekolo e khahlanong le hlobo le metsoako, e bakang botsitso ba viscosity ea sehlahisoa le litšenyehelo tsa tlhahiso li ameha; Ho paka ka mokhoa oa matsoho, matla a mosebetsi, litšenyehelo tse phahameng tsa basebetsi; Tekanyo ea boiketsetso ea taolo ea karabelo e tlase ho feta ea ts'ebetso ea khase, kahoo ho nepahala ha taolo ho batla ho le tlase. Ha ho bapisoa le mokhoa oa khase ea khase, ho hlokahala mekhoa e rarahaneng ea ho tsosolosa solvent.

Ka ntlafatso ea lehae la hydroxypropyl methyl celluloseHPMCthekenoloji ea tlhahiso, likhoebo tse ling ka boqapi bo ikemetseng bo tsoelang pele, mokhoa o moholo oa mokelikeli oa kettle o ntlafalitsoe ka mokhoa o tlokomang, mme o na le litšobotsi tsa ona tsa tekheniki. Anxin k'hemistri e sebelisa mokhoa oa pele oa tlhahiso ea HPMC, eseng feela ts'ebetso ea tlhahiso e utloahalang, litekanyetso tsa taolo ea ts'ebetso li nepahetse ebile li ka tšeptjoa, tšebeliso e feletseng le e utloahalang ea lisebelisoa tse tala le litšobotsi tse ling, 'me tekanyo ea phetoho ea sehlahisoa ke junifomo, karabelo e feletseng ka ho feletseng, tharollo ea ponaletso e ntle,' me ka nako e ts'oanang ho netefatsa botsitso ba boleng ba sehlahisoa. Mohala oa tlhahiso ea HPMC oa likhoebo tse ling e bile phetoho e ikemetseng, ho fihlela litlhoko tsa taolo ea mochini oa DCS, lisebelisoa tse kenyelletsang metsi, lisebelisoa tse tala li ka sebelisoa ho lekanya ka nepo le ho eketsa sistimi ea DCS, taolo ea mocheso le khatello ts'ebetsong ea karabelo kaofela li lemohuoa taolo ea othomathike ea DCS le ho beha leihlo hole, Mabapi le ho khonahala, ts'epahalo, botsitso le polokeho ea tlhahiso, ho hlakile hore ha e fokotse mokhoa oa tlhahiso ea setso ha o bapisoa le mokhoa oa setso o ntlafalitsoeng feela. matla, empa hape e ntlafatsa tikoloho ea ts'ebetso setšeng.