Qiimaha 2019 Qiimaha Indhaha Shiinaha ee tayo sare leh ee HPMC E4000
Qanacsanaanta macaamiishu waa hadafkayaga ugu muhiimsan. Waxaan ilaalinaa heer joogto ah oo xirfad, tayo, kalsooni iyo adeeg ah sannadka 2019 Heerka Daawashada Indhaha Shiinaha ee Tayada Sare lehHPMCQiimaha E4000, Waxaan diiradda saarnaa sameynta alaab tayo sare leh si aan u siino taageero macaamiisheenna si loo xaqiijiyo xiriir jacayl oo muddo dheer ah oo guul-guul leh.
Qanacsanaanta macaamiishu waa hadafkayaga koowaad. Waxaan ilaalinaa heer joogto ah oo xirfad, tayo, kalsooni iyo adeeg ahCellulose-ka Hydroxypropyl Methyl ee Shiinaha, HPMCIyada oo leh noocyo badan, tayo wanaagsan, qiimo macquul ah iyo naqshado casri ah, alaabtayadu si weyn ayaa loogu isticmaalaa qurxinta iyo warshadaha kale. Badeecadahayagu si weyn ayaa loo aqoonsan yahay oo loogu kalsoon yahay isticmaalayaashu waxayna dabooli karaan baahiyaha dhaqaale iyo bulsho ee isbeddelaya si joogto ah.
Sharaxaadda Badeecada
Magaca Kiimikada: Hydroxypropyl Methylcellulose,HPMC,Methyl Hydroxypropyl cellulose,MHPC,Cellulose Ethers
Foomamka Molekuleeri: C3H7O *
Miisaanka Molekule: 59.08708
Muuqaalka: Budada Cad
Koodhka HS: 39123900
Lambarka CAS:9004-65-3
Hydroxypropyl Methyl Cellulose (HPMC) waxaa sidoo kale loo yaqaan Methyl Hydroxypropyl Cellulose MHPC, hypromellose, waa noocyo ka mid ah cellulose ether-ka aan ionic ahayn, kuwaas oo ah budo dabiici ah oo midab cad ilaa midab cad ah leh, kuwaas oo u adeega sidii dhumuc-dheereeye, xidhe, surfactant, colloid ilaalin ah, saliideeye, emulsifier, iyo ganaaxyo iyo gargaar dayactir biyood oo caadi ah. Intaa waxaa dheer, noocyadan ethers-ka cellulose waxay muujinayaan sifooyinka jelitaanka tamarta, firfircoonida dheef-shiid kiimikaadka, heerka iska caabbinta ensaymka, ur hoose iyo qaab, iyo xasilloonida pH.
Hydroxypropyl Methyl Cellulose HPMC waxaa si weyn loogu isticmaalaa dhismaha, dawooyinka, cuntada, balaastikada, saabuunta, rinjiga, dharka iyo kuwa kale oo badan. Si fudud ayaan u bixin karnaa HPMC tayo leh oo joogto ah, waxaan sidoo kale u qaabeyn karnaa Hydroxypropyl Methyl Cellulose HPMC oo la beddelay iyadoo loo eegayo baahiyaha iibsadaha. Ka dib marka la beddelo, waxaan heli karnaa badeecada ama adeegga leh waqti furan oo aad u dheer, ka-hortagga slag-ka weyn, shaqeyn heer sare ah iyo kuwo kale oo badan.
Qeexitaanka Kiimikada
| Faahfaahinta | HPMC 60E ( 2910) | HPMC 65F (2906) | HPMC 75K ( 2208) |
| Heerkulka jel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (cps, 2% Xal) | 3, 5, 6, 15, 50, 100, 400, 400, 40000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Heerka Dhismaha Hydroxypropyl Methylcellulose (HPMC)
Heerka Dhismaha Hydroxypropyl Methylcellulose (HPMC) waa kuwa biyaha ku milma, kuwa aan ionic ahayn, kuwaas oo loo bixiyo sidii budo socota oo xor ah ama qaab granular ah. HPMC waxaa loo arki karaa erey guud oo loogu talagalay ethers cellulose isku dhafan ee etherification. Waxyaabaha ay ku badan tahay ethers-kan cellulose waa methoxylation. Intaa waxaa dheer, falcelinta waxaa lagu gaari karaa propylene oxide. HPMC waxaa si weyn loogu isticmaalaa putty derbiga, skim coat, buuxinta kala-goysyada, is-le'egta, dhejisyada taayilka, hoobiye isku dhafan oo qalalan, sibidh iyo balastar ku salaysan gypsum iwm. Waxaan bixin karnaa labadaba heerka aan wax laga beddelin iyo heerka HPMC ee wax laga beddelay, kaas oo leh waqti dheer oo furan, haynta biyaha wanaagsan, shaqaynta aadka u fiican iyo iska caabin wanaagsan iwm.
| Fasalka Dhismaha HPMC | Viscosity (NDJ, mPa.s, 2%) | Viscosity (Brookfield, mPa.s, 2%) |
| HPMC TK400 | 320-480 | 320-480 |
| HPMC TK60M | 48000-72000 | 24000-36000 |
| HPMC TK100M | 80000-120000 | 40000-55000 |
| HPMC TK150M | 120000-180000 | 55000-65000 |
| HPMC TK200M | 180000-240000 | 70000-80000 |
Codsiyada Caadiga ah
Malaas Sibidh / Hoobiye isku darka qalalan
• Baahida biyaha oo korodhay: waqtiga furan oo kordhay, aagga spry-ga oo la ballaariyay iyo qaab-dhismeed dhaqaale ahaan wanaagsan.
• Faafitaan fudud iyo iska caabinta hoos u dhaca oo la hagaajiyay sababtoo ah joogteynta oo la hagaajiyay.
•Qaacido fudud oo qalalan oo ay ugu wacan tahay milmida biyaha qabow: sameynta burooyinka si fudud ayaa looga fogaan karaa, taasoo ku habboon taayirrada culus.
• Haynta biyaha oo wanaagsan: ka hortagga lumitaanka dareeraha ee substrate-ka, biyaha ku habboon waxaa lagu hayaa isku dar ah taasoo damaanad qaadaysa waqti dheer oo shub ah.
Xabagta Foornada
• Isku-dhejinta iyo iska caabinta simbiriirixan oo la hagaajiyay: gaar ahaan taayirrada culus.
•Shaqayn wanaagsan: saliidaynta iyo balaastikada balaastikada ayaa la hubiyaa, hoobiyaha waxaa loo isticmaali karaa si fudud oo dhakhso badan.
• Haynta biyaha oo wanaagsan: waqtiga furitaanka oo dheeraada ayaa ka dhigi doona taayirada mid waxtar badan leh.
Nidaamka Dahaarka Dibadda iyo Dhammaystirka (EIFS)
• Hoos u dhac ku yimid gelitaanka hawada iyo qaadashada biyaha.
• Ku dhegid wanaagsan.
• Awood qoyn oo wanaagsan oo loogu talagalay guddiga EPS iyo substrate-ka.
Jaakad derbi/Jaakad jilicsan
•Kordhinta wax soo saarka hoobiyaha: iyadoo ku xiran miisaanka isku darka qalalan iyo qaacidada ku habboon, HPMC waxay kordhin kartaa mugga hoobiyaha.
• Haynta biyaha: heerka biyaha ee ugu sarreeya ee ku jira slurry.
• Ka hortagga dhogorta: marka la faafinayo dahaarka qaro weyn, dahaarka waa laga fogaan karaa.
Buuxiye Dildilaac ah
· Haynta biyaha waxay hubineysaa waqti dheer oo shaqo.
· Iska caabbinta jabka: awoodda isku xidhka hoobiyaha oo la hagaajiyay.
· Shaqo wanaagsan: dhumuc iyo balaastik sax ah.
Is-siman
• Wax saameyn ah kuma yeelanayo dareeraha slurry-ka iyadoo uu hooseeyo viscosity-ga
HPMC, halka astaamaheeda haysashada biyaha ay hagaajinayaan waxqabadka dhammaadka dusha sare.
• Ka ilaalinta biyaha soo daadanaya iyo wasakhda walxaha.
Saabuunta Hydroxypropyl Methylcellulose (HPMC)
Saabuunta Hydroxypropyl Methylcellulose (HPMC) waa budo cad oo leh milmi biyo oo wanaagsan. Waxay leedahay dhumuc, dhejis, kala firdhi, emulsifying, filim, la hakiyey, nuugid, jel, iyo sifooyin ilaalin ah oo kolloid ah oo ku saabsan dhaqdhaqaaqa dusha sare iyo ilaalinta sifooyinka shaqada qoyaanka iwm. Darajada saabuunta HPMC waxaa dusha sare lagu daaweeyaa iyada oo loo marayo habka wax soo saarka gaarka ah, waxay bixin kartaa daxal sare oo leh xal degdeg ah iyo dib u dhac. Darajada saabuunta HPMC waxaa si dhakhso ah loogu milmi karaa biyo qabow waxayna kordhin kartaa saameyn dhumuc weyn. Hydroxypropyl Methyl Cellulose HPMC waxaa loo isticmaalaa dareeraha saabuunta, nadiifiyaha gacmaha, jelka khamriga, shaambo, dareeraha dhaqidda, kiimikooyinka nadiifinta sida wakiilka dhumucda iyo kala firdhinta
| Saabuunta Fasalka HPMC | Viscosity (NDJ, mPa.s, 2%) | Viscosity (Brookfield, mPa.s, 2%) |
| HPMC TK100MS | 80000-120000 | 40000-55000 |
| HPMC TK150MS | 120000-180000 | 55000-65000 |
| HPMC TK200MS | 180000-240000 | 70000-80000 |
Daawada Hydroxypropyl Methylcellulose (HPMC)
Darajada Daawada Hydroxypropyl Methylcellulose (HPMC) waa daawada kaabista iyo kaabisyada daawada Hypromellose, waxay waxtar u leedahay sidii binder, maadaama aysan la falgalin daawooyinka. Waxay leedahay xasillooni sare, dabeecad aan ionic ahayn waxaana si weyn loogu isticmaalaa sidii binder loogu talagalay granulation. Sababtoo ah dabeecadda dhirta laga soo qaatay iyo xasilloonida qoyaanka ee aadka u fiican, hypromellose waxay beddeshaa gelatin-ka soo saarista kaabsulka adag.
QualiCell® Cellulose ether wuxuu ka kooban yahay methyl cellulose (USP, EP, BP, CP) iyo saddex nooc oo beddelka ah oo ah hydroxypropyl methyl cellulose (hypromellose USP, EP, BP, CP) mid walbana wuxuu ku diyaarsan yahay darajooyin kala duwan oo ku kala duwan viscosity-ga. Badeecadaha HPMC waxaa laga soo qaatay suuf dabiici ah oo la safeeyey iyo saxarka alwaaxa, iyagoo buuxinaya dhammaan shuruudaha USP, EP, BP, oo ay weheliso Shahaadooyinka Kosher iyo Xalaal.
QualiCell® HPMC waxay bixisaa shaqooyin kala duwan sida haynta biyaha, kolloid ilaalin ah, firfircoonida dusha sare, sii dayn joogto ah. Waa isku-dhis aan ionic ahayn oo u adkaysta milixda oo deggan baaxadda pH-ga oo ballaaran. Codsiyada caadiga ah ee HPMC waa xidhmo loogu talagalay qaababka qiyaasta adag sida kiniiniyada iyo granules ama dhumuc-dhererka loogu talagalay codsiyada dareeraha ah.
Waxaa lagu soo saaraa warshad wax soo saar oo gaar ah oo ku taal Degmada Cusub ee Bohai halkaas oo walxaha ceeriin ee ku salaysan dhirta loo beddelo walxahan daawada ee gaarka ah.
Darajooyin kala duwan oo viscosity ah ayaa la heli karaa iyadoo loo eegayo baahidaada. HPMC waxay ku timaadaa viscosity kala duwan oo u dhexeeya 3 ilaa 200,000 cps, waxaana si weyn loogu isticmaali karaa dahaarka kiniinka, granulation-ka, xidhka, dhumuc-dhejinta, xasilinta iyo sameynta kaabsal HPMC khudaar ah. Kiniiniyada matrix-ka sii deynta ee joogtada ah oo ku salaysan waxyaabaha ka soo baxa cellulose-ka ee biyaha ku milma ayaa ah habka ugu fudud, kharash-ool ah iyo habka ugu caansan ee wax looga beddelo sii deynta daawada.
Qeexitaanka Kiimikada
| Hypromellose Faahfaahinta | 60E(2910) | 65F(2906) | 75K(2208) |
| Heerkulka jel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (cps, 2% Xal) | 3, 5, 6, 15, 50, 100, 400, 400, 40000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Heerka Badeecada
| Heerka Hypromellose | Viscosity (cps) | Faallo |
| HPMC 60E5 (E5) | 4.0-6.0 | Hypromellose 2910 |
| HPMC 60E6 (E6) | 4.8-7.2 | |
| HPMC 60E15 (E15) | 12.0-18.0 | |
| HPMC 60E4000 (E4M) | 3200-4800 | |
| HPMC 65F50 (F50) | 40-60 | Hypromellose 2906 |
| HPMC 75K100 (K100) | 80-120 | Hypromellose 2208 |
| HPMC 75K4000 (K4M) | 3200-4800 | |
| HPMC 75K100000 (K100M) | 80000-120000 |
Goobta Codsiga
| Codsiga Waxyaabaha Daawada ah ee Farmashiyaha | Fasalka Farmashiyaha HPMC | Qiyaasta |
| Jilciye Badan | 75K4000,75K100000 | 3-30% |
| Kareemyada, Jellada | 60E4000,75K4000 | 1-5% |
| Diyaarinta Indhaha | 60E4000 | 01.-0.5% |
| Diyaarinta Dhibcaha Indhaha | 60E4000 | 0.1-0.5% |
| Wakiilka Joojinta | 60E4000, 75K4000 | 1-2% |
| Daawooyinka lidka asiidhka | 60E4000, 75K4000 | 1-2% |
| Kiniiniyada Galka | 60E5, 60E15 | 0.5-5% |
| Qoyanta Qoyan ee Shirka | 60E5, 60E15 | 2-6% |
| Dahaarka Kiniiniga | 60E5, 60E15 | 0.5-5% |
| Matrix-ka Sii-deynta La Xakameeyay | 75K100000,75K15000 | 20-55% |
Heerka Cuntada Hydroxypropyl Methylcellulose (HPMC)
Heerka Cuntada Hydroxypropyl Methylcellulose (HPMC) waa cellulose-ka aan biyaha ku milmin ee aan ionic ahayn ee Hypromellose, oo loogu talagalay codsiyada cuntada iyo kaabista cuntada.
Xanjada Cellulose ee heerka cuntada waa qayb cunto oo gaar ah, heerarka cuntadu waa noocyo kala duwan oo ah hydroxypropyl methyl cellulose (E464) iyo methyl cellulose (E461). Waxaa lagu soo saaraa warshad wax soo saar oo gaar ah oo ku taal Degmada Cusub ee Bohai halkaas oo walxaha ceeriin ee ku salaysan dhirta loo beddelo maaddooyinkan cuntada gaarka ah.
Darajooyinka cuntada ee QualiCell® waxay leeyihiin sifooyin gaar ah oo la jeleeyo marka la kululeeyo. Sababtoo ah jelitaankan kulaylka, darajooyinka cuntada ee QualiCell® waxay siiyaan qaniinyada alaabada ku salaysan dhirta iyo xasilloonida cuntada dib loo habeeyay. Darajooyinka cuntadu waxay leeyihiin sifooyin gaar ah oo jeleeyo marka la kululeeyo. Sababtoo ah jelitaankan kulaylka, heerka cuntada ee HPMC wuxuu bixiyaa qaniinyada alaabada ku salaysan dhirta, xasilloonida cuntada dib loo habeeyay iyo jilicsanaanta rootiga aan lahayn gluten.
Baakad
Bacaha warqadda ah ee 25kg oo leh gudaha PE;
25kg/Faybar Durbaan
Qanacsanaanta macaamiishu waa hadafkayaga ugu muhiimsan. Waxaan ilaalinaa heer xirfadeed oo joogto ah, tayo, kalsooni iyo adeeg sanadka 2019 Qiimaha HPMC E4000 ee Shiinaha ee tayada sare leh, Waxaan diiradda saarnaa sameynta alaab tayo sare leh si aan u siino taageero macaamiisheenna si loo xaqiijiyo xiriir jacayl oo muddo dheer ah oo guul-guul ah.
2019 Tayo sareCellulose-ka Hydroxypropyl Methyl ee Shiinaha, HPMC, Iyada oo leh noocyo badan, tayo wanaagsan, qiimo macquul ah iyo naqshado casri ah, alaabtayadu si weyn ayaa loogu isticmaalaa qurxinta iyo warshadaha kale. Badeecadahayaga waxaa si weyn u aqoonsan oo u aamina dadka isticmaala waxayna dabooli karaan baahiyaha dhaqaale iyo bulsho ee isbeddelaya si joogto ah.
