Hydroxypropyl Methylcellulose (HPMC)i polymer inonyungudika nemvura inowanzoshandiswa mumishonga, chikafu, cosmetic, uye maindasitiri ekuvaka. Hunyoro hweHPMC hunoita basa rakakosha mukugadzirisa nekugadzikana kwayo. Inobata rheological properties, solubility, uye sherufu yehupenyu hwezvinhu. Kunzwisisa hunyoro hwemukati kwakakosha pakuumbwa kwayo, kuchengetedza, uye kupera-kushandiswa kwekushandisa.
Kunyorova Kwemukati kweHPMC
Kunyorova kweAnxinCel®HPMC kunowanzo kutsanangurwa nemamiriro ekuita uye giredhi chaiyo yepolymer inoshandiswa. Hunyoro hwemukati hunogona kusiyana zvichienderana neyakabikwa, mamiriro ekuchengetera, uye kuomesa maitiro. Inowanzotaridzwa sechikamu chehuremu hwemuenzaniso usati waoma uye mushure mekuoma. Kune maindasitiri ekushandisa, hunyoro hwakakosha, sezvo hunyoro hwakanyanya hunogona kutungamira mukuderedzwa, kudhumhana, kana kudzikisira kuita kweHPMC.
Hunyoro hweHPMC hunogona kubva pa5% kusvika pa12%, asi hunyoro huri pakati pe7% ne10%. Hunyoro hwemukati hunogona kutariswa nekuomesa sampuli pane imwe tembiricha (semuenzaniso, 105 ° C) kusvika yasvika pahuremu hunogara. Musiyano wehuremu usati waoma uye mushure unomiririra hunyoro.
Zvinhu Zvinokanganisa Hunyoro Zvemukati muHPMC
Zvinhu zvakati wandei zvinogona kukanganisa hunyoro hweHPMC:
Humidity uye Kuchengeta Mamiriro:
Hunyoro hwepamusoro kana kusachengeteka zvakanaka kunogona kuwedzera mwando weHPMC.
HPMC is hygroscopic, zvichireva kuti inowanzotora hunyoro kubva kumhepo yakatenderedza.
Kurongedza uye kuiswa chisimbiso kwechigadzirwa kunogona kuderedza kunyura kwehunyoro.
Processing Conditions:
Iyo tembiricha yekuomesa uye nguva panguva yekugadzira inogona kukanganisa yekupedzisira mwando.
Kuomesa nekukasira kunogona kuita kuti hunyoro hurambe huripo, nepo kuomeswa zvishoma nezvishoma kunogona kukonzera kuti mwando uchengetedzwe.
HPMC Giredhi:
Magiredhi akasiyana eHPMC (semuenzaniso, low viscosity, medium viscosity, kana high viscosity) inogona kunge iine hunyoro hwakasiyana zvishoma nekuda kwekusiyana kwemaitiro nemagadzirirwo.
Supplier Specifications:
Vatengesi vanogona kupa HPMC nehunyoro hwakatsanangurwa hunoenderana nemaindasitiri zviyero.
Typical Moisture Content yeHPMC neGiredhi
Hunyoro hweHPMC hunosiyana zvichienderana negiredhi uye chinangwa chekushandiswa. Heino tafura inoratidza akajairwa hunyoro huwandu hwemagiredhi akasiyana eHPMC.
| HPMC Giredhi | Viscosity (cP) | Hunyoro (%) | Applications |
| Low Viscosity HPMC | 5-50 | 7 – 10 | Pharmaceuticals (mapiritsi, capsules), zvizorwa |
| Medium Viscosity HPMC | 100 - 400 | 8 – 10 | Pharmaceuticals (inodzorwa kusunungurwa), chikafu, zvinonamira |
| High Viscosity HPMC | 500 - 2000 | 8 – 12 | Kuvaka (sement-based), chikafu (thickening agent) |
| Pharmaceutical HPMC | 100 - 4000 | 7 – 9 | Mahwendefa, capsule coatings, gel maitiro |
| Chikafu-Grade HPMC | 50 - 500 | 7 – 10 | Kuwedzera kwekudya, emulsification, kupfeka |
| Kuvaka Giredhi HPMC | 400 - 10000 | 8 – 12 | Dhaka, zvinonamatira, plasters, yakaoma misanganiswa |
Kuedzwa uye Kugadziriswa kweKunyorova Kwemukati
Pane nzira dzakati wandei dzekutarisa hunyoro hweHPMC. Nzira mbiri dzinonyanya kuzivikanwa ndeidzi:
Gravimetric Method (Kurasikirwa paKuomesa, LOD):
Iyi ndiyo nzira inonyanya kushandiswa pakuona hunyoro. Huremu hunozivikanwa hweHPMC hunoiswa muhovhoni yekuomesa yakagadzika pa105°C. Mushure menguva yakatarwa (kazhinji maawa 2-4), sampuli inoyerwa zvakare. Musiyano wehuremu unopa hunyoro hwemukati, hunotaridzwa sechikamu chehuremu hwekutanga sampuli.
Karl Fischer Titration:
Iyi nzira ndeyechokwadi kupfuura iyo LOD uye inosanganisira kemikari yekuita inoyera huwandu hwemvura. Iyi nzira inowanzo shandiswa kana kunyatsoita mwando kunodiwa.
Mhedzisiro yeKunyorova Kwemukati paHPMC Zvivakwa
Hunyoro hweAnxinCel®HPMC hunokanganisa kushanda kwayo mumashandisirwo akasiyana-siyana:
Viscosity:Hunyoro hwemukati hunogona kukanganisa viscosity yeHPMC mhinduro. Hunyoro hwepamusoro hunogona kuwedzera viscosity mune mamwe magadzirirwo, nepo hunyoro hunyoro hunogona kukonzera kuderera kweviscosity.
Solubility:Kuwedzera mwando kunogona kutungamira mukusangana kana kudzikisira kunyungudika kweHPMC mumvura, zvichiita kuti isanyanya kushanda kune mamwe maapplication, akadai seanodzorwa kuburitsa maumbirwo muindasitiri yemishonga.
Kugadzikana:HPMC inowanzogadzikana munzvimbo dzakaoma, asi hunyoro hwepamusoro hunogona kukonzera kukura kwehutachiona kana kuparara kwemakemikari. Nechikonzero ichi, HPMC inowanzo chengetwa mumidziyo yakavharwa munzvimbo dzakadzika-hunyoro.
Hunyoro Zvemukati uye Packaging yeHPMC
Nekuda kweiyo hygroscopic chimiro cheHPMC, kurongedza kwakakodzera kwakakosha kudzivirira kunyura kubva mumhepo. HPMC inowanzoiswa mumabhegi anodzivirira hunyoro kana midziyo yakagadzirwa nezvinhu zvakaita se polyethylene kana multi-layer laminates kuti idzivirire kubva pakunyorova. Iyo yekurongedza inovimbisa kuti hunyoro hunoramba huri mukati meiyo yaunoda panguva yekuchengetera nekufambisa.
Moisture Content Control in Manufacturing
Panguva yekugadzirwa kweHPMC, zvakakosha kutarisa nekudzora hunyoro kuchengetedza kunaka kwechigadzirwa. Izvi zvinogona kuwanikwa kuburikidza ne:
Drying Techniques:HPMC inogona kuomeswa uchishandisa mhepo inopisa, vacuum drying, kana rotary dryer. Tembiricha uye nguva yekuomeswa inofanirwa kuvandudzwa kudzivirira zvese pasi-kuwomeswa (yakanyanya mwando yemukati) uye zvakanyanya-kuomesa (izvo zvinogona kutungamirira mukupisa kwekupisa).
Environmental Control:Kuchengeta nzvimbo inodzorwa ine hunyoro hwakaderera munzvimbo yekugadzira kwakakosha. Izvi zvinogona kusanganisira dehumidifiers, air conditioning, uye kushandiswa kwema sensors ekunyorova kutarisa mamiriro emuchadenga panguva yekugadziriswa.
Hunyoro hwe HPMCkazhinji inowira mukati mechikamu che7% kusvika 10%, kunyangwe ichigona kusiyana zvichienderana negiredhi, mashandisirwo, uye kuchengetedza mamiriro. Hunyoro hwemukati chinhu chakakosha parameter inokanganisa rheological properties, solubility, uye kugadzikana kweAnxinCel®HPMC. Vagadziri uye vanogadzira vanofanirwa kunyatso kudzora uye kutarisa hunyoro hwemukati kuti ive nechokwadi chekushanda kwakakwana mumashandisirwo avo chaiwo.
Nguva yekutumira: Jan-20-2025