Hydroxypropyl methylcellulose (HPMC)isiri-ionic cellulose ether inoshandiswa zvakanyanya mukuvaka zvinhu, mishonga, chikafu, zvizoro uye mamwe maindasitiri. Iyo huru tekinoroji zviratidzo zveHPMC zvinosanganisira zvemuviri uye makemikari zvivakwa, solubility, viscosity, dhigirii rekutsiva, nezvimwe.
1. Chitarisiko uye unhu hunokosha
HPMC inowanzova chena kana isina-chena hupfu, isinganhuhwi, isinganakidze, isina chepfu, ine mvura yakanaka yekunyungudika uye kugadzikana. Inogona kukurumidza kupararira uye kunyungudika mumvura inotonhora kuita inoonekera kana zvishoma turbid colloidal mhinduro, uye ine kushomeka kunyungudika muorganic solvents.
2. Viscosity
Viscosity ndeimwe yeakanyanya kukosha tekinoroji zviratidzo zveHPMC, iyo inotaridza mashandiro eAnxinCel®HPMC mumashandisirwo akasiyana. The viscosity yeHPMC inowanzoyerwa se2% aqueous solution pa20°C, uye common viscosity range inobva pa5 mPa·s kusvika 200,000 mPa·s. Iyo yakakwirira iyo viscosity, iyo yakasimba iyo thickening mhedzisiro yemhinduro uye zviri nani iyo rheology. Kana ichishandiswa mumaindasitiri akadai sekuvaka uye mushonga, iyo yakakodzera viscosity giredhi inofanirwa kusarudzwa zvinoenderana nezvinodiwa chaizvo.
3. Methoxy uye Hydroxypropoxy Content
Izvo zvemakemikari zvimiro zveHPMC zvinonyanya kutsanangurwa neiyo methoxy (-OCH₃) uye hydroxypropoxy (-OCH₂CHOHCH₃) madhigirii ekutsiva. HPMC ine madhigirii ekutsiva akasiyana anoratidza kunyungudika kwakasiyana, chiitiko chepamusoro uye tembiricha yegelation.
Methoxy Content: Kazhinji pakati pe19.0% ne30.0%.
Hydroxypropoxy Content: Kazhinji pakati pe4.0% ne12.0%.
4. Hunyoro Content
Kunyorova kweHPMC kunowanzo kudzorwa pa ≤5.0%. Iyo yakakwira mwando yemukati inozokanganisa kugadzikana uye kushandisa mhedzisiro yechigadzirwa.
5. Madota Zvirimo
Madota ndiyo inosara mushure mekunge HPMC yapiswa, kunyanya kubva mumunyu unoshandiswa mukugadzira. Izvo zvinyorwa zvemadota zvinowanzodzorwa pa ≤1.0%. Madota akawandisa anogona kukanganisa kujeka uye kuchena kweHPMC.
6. Solubility uye pachena
HPMC ine mvura yakanaka solubility uye inogona kukurumidza kunyungudika mumvura inotonhora kuita yunifomu colloidal mhinduro. Kujeka kwemhinduro kunoenderana nekuchena kweHPMC uye kuparara kwayo. Yepamusoro-mhando yeHPMC mhinduro inowanzo jeka kana kuti ine mukaka zvishoma.
7. Gel Temperature
HPMC aqueous solution ichaita gel pane imwe tembiricha. Kupisa kwayo gel kunowanzova pakati pe50 ne90 ° C, zvichienderana nemukati methoxy uye hydroxypropoxy. HPMC ine yakaderera methoxy yemukati ine yakakwira gel tembiricha, nepo HPMC ine yakakwira hydroxypropoxy content ine yakaderera gel tembiricha.
8. pH kukosha
Iyo pH kukosha kweAnxinCel®HPMC aqueous solution inowanzova pakati pe5.0 ne8.0, iyo isina kwayakarerekera kana isina kusimba alkaline uye yakakodzera kune dzakasiyana siyana dzekushandisa.
9. Chikamu Saizi
Iko kunaka kweHPMC kunowanzo kuratidzwa sechikamu chinopfuura nepa80-mesh kana zana-mesh skrini. Zvinowanzodiwa kuti ≥98% ipfuure nepa80-mesh skrini kuti ive nechokwadi chekuti ine yakanaka dispersibility uye solubility kana ikashandiswa.
10. Heavy metal content
Iyo inorema simbi yemukati (senge lead uye arsenic) yeHPMC inofanirwa kutevedzera yakakodzera indasitiri zviyero. Kazhinji, iyo inotungamira yemukati ndeye ≤10 ppm uye iyo arsenic yemukati ndeye ≤3 ppm. Kunyanya mune chikafu uye chemishonga giredhi HPMC, izvo zvinodikanwa zveheavy metal content zvakanyanya kuomarara.
11. Microbial zviratidzo
Pagiredhi yemishonga uye yechikafu AnxinCel®HPMC, kusvibiswa kwehutachiona kunofanirwa kudzorwa, kusanganisira huwandu hwekoloni, mold, mbiriso, E. coli, zvichingodaro, kazhinji zvinoda:
Total colony count ≤1000 CFU/g
Yakazara mold uye mbiriso kuverenga ≤100 CFU/g
E. coli, Salmonella, nezvimwewo hazvifanirwe kuonekwa
12. Nzvimbo huru dzekushandisa
HPMC inoshandiswa zvakanyanya mumaindasitiri mazhinji nekuda kwekukora kwayo, kuchengetedza mvura, kugadzira firimu, lubrication, emulsification uye zvimwe zvivakwa:
Indasitiri yekuvaka: Seanokora uye anochengetedza mvura mudhaka simende, putty poda, anonamira mataira, uye inovhara mvura kuti ivandudze kuita kwekuvaka.
Indasitiri yemishonga: Inoshandiswa seanonamira, inosimudzira-inoburitsa zvinhu, uye capsule shell raw material yemapiritsi ezvinodhaka.
Indasitiri yechikafu: inoshandiswa se emulsifier, stabilizer, thickener, inoshandiswa mujelly, zvinwiwa, zvakabikwa, nezvimwe.
Indasitiri yemazuva ese yemakemikari: inoshandiswa se thickener uye emulsifier stabilizer mune zvigadzirwa zvekuchengetedza ganda, detergents, uye shampoos.
The technical zviratidzo zveHPMCzvinosanganisira viscosity, dhigirii rekutsiva (hydrolyzed boka content), unyoro, madota, pH kukosha, gel tembiricha, fineness, heavy metal content, etc. Izvi zviratidzo zvinotarisa kushanda kwayo kwekushanda munzvimbo dzakasiyana. Paunenge uchisarudza HPMC, vashandisi vanofanirwa kuona iyo yakakodzera zvirevo zvinoenderana nezvinodiwa zvekushandisa kuti ive nechokwadi chekushandisa kwakanyanya.
Nguva yekutumira: Feb-11-2025