Hydroxypropyl methylcellulose inogona kuvandudza anti-kupararira pfuma yesamende dhaka

Hydroxypropyl methylcellulose (HPMC)chinhu chakakosha chepolymer chinoshandiswa zvakanyanya mumunda wezvivakwa zvekuvaka, kunyanya mumatope esimende. Iyo inovandudza anti-kupararira pfuma yesamende dhaka nekuita kwayo kwakanakisa, nekudaro ichivandudza zvakanyanya kuita kwekuvaka uye kusimba kwedhaka.

1. Zvinhu zvakakosha zvehydroxypropyl methylcellulose

HPMC is a non-ionic cellulose ether inowanikwa nekemikari kugadzirisa selulosi chaiyo. Iyo ine yakanaka solubility yemvura, kuchengetwa kwemvura uye kunamatira, uye inoratidza yakanyanya kugadzikana kwemakemikari uye biocompatibility. Mune simende-based materials, AnxinCel®HPMC inonyanya kuvandudza kushanda kwezvinhu nekugadzirisa hydration reaction uye viscosity maitiro.

2. Nzira yekuvandudza anti-kupararira pfuma yesamende dhaka

Anti-dispersion property (Anti-dispersion property) zvinoreva kugona kwesamende dhaka kuti rirambe rakaperera pasi pekukweshwa kwemvura kana kudengenyeka. Mushure mekuwedzera HPMC, maitiro ayo ekuvandudza anti-kupararira anonyanya kusanganisira zvinotevera zvinhu:

2.1. Kuwedzerwa kuchengetedza kwemvura

HPMC mamorekuru anogona kugadzira hydration firimu pamusoro pemasimende zvimedu, izvo zvinonyatso kudzikisa huwandu hwekubuda kwemvura uye inovandudza kuchengetedza kwemvura kwedhaka. Kuchengetwa kwemvura kwakanaka hakungodzikisi njodzi yekurasikirwa kwemvura uye kuputika kwedhaka, asi zvakare kunoderedza kupararira kwezvikamu zvinokonzerwa nekurasikirwa kwemvura, nekudaro kunowedzera anti-kupararira.

2.2. Wedzera viscosity

Rimwe remabasa makuru eHPMC nderekuwedzera zvakanyanya viscosity yedhaka. High viscosity inobvumira zvimedu zvakasimba mudhaka kuti zvinyatsobatanidzwa, zvichiita kuti zvive zvakaoma kupararira kana zvichiiswa kune simba rekunze. Iyo viscosity yeHPMC inoshanduka nekuchinja kwekutarisa uye tembiricha, uye sarudzo inonzwisisika yehuwandu hwekuwedzera inogona kuita yakanakisa mhedzisiro.

2.3. Yakavandudzwa thixotropy

HPMC inopa dhaka rakanaka thixotropy, kureva kuti, ine high viscosity mu static state, uye viscosity inoderera kana ichiiswa kushear simba. Hunhu hwakadaro hunoita kuti dhaka rive nyore kupararira panguva yekuvaka, asi rinogona kukurumidza kudzoreredza viscosity munzvimbo yakamira kudzivirira kupararira uye kuyerera.

2.4. Gadzirisa maitiro ekushandisa

HPMC yakagovaniswa zvakaenzana mudhaka, iyo inogona kuumba bhiriji pakati pezvimedu uye kugadzirisa simba rekubatanidza pakati pezvimedu. Pamusoro pezvo, chiitiko chepamusoro cheHPMC chinogona zvakare kuderedza kushushikana kwepasi pakati pemasimende, nekudaro ichiwedzera kusimudzira mashandiro e-anti-dispersion.

3. Maitiro ekushandisa uye zvakanakira

Mumapurojekiti chaiwo, dhaka resimende rakasanganiswa neHPMC rinoratidza kuvandudzwa kwakanyanya mukurwisa-kupararira kuita. Izvi zvinotevera zvimwe zvazvakanakira:

Kuvandudza kushanda kwekuvaka: Doka rine yakasimba anti-kupararira mashandiro ari nyore kudzora panguva yekuvaka uye haawanzo kupatsanurwa kana kubuda ropa.

Natsiridza hunhu hwepamusoro: Kunamira kwedhaka pachigadziko kunowedzerwa, uye nepamusoro mushure mekupurasita kana paving inopfava.

Wedzera kusimba: Deredza kurasikirwa kwemvura mukati medhaka, kuderedza kuwedzera kwevoids kunokonzerwa nekupararira, uye nokudaro kuvandudza kusimba uye kusimba kwedhaka.

4. Kufurira zvinhu uye maitiro ekugadzirisa

Mhedzisiro yeHPMC yekuwedzera inowirirana zvakanyanya nedosage yayo, uremu hwemamorekuru uye mamiriro ezvakatipoteredza. Kuwedzerwa kwehuwandu hwakakodzera hweHPMC kunogona kuvandudza mashandiro edhaka, asi kuwedzera zvakanyanya kunogona kutungamira kune yakawandisa viscosity uye kukanganisa kushanda kwekuvaka. Mazano ekugadzirisa anosanganisira:

Kusarudza HPMC ine huremu hwakakodzera hwemamorekuru uye dhigirii rekutsiva: HPMC ine uremu hwepamusoro hwemamorekuru inopa viscosity yepamusoro, asi kuita uye kushanda kunoda kuenzana zvichienderana nemashandisirwo chaiwo.

Nyatsodzora huwandu hwekuwedzera: HPMC inowanzowedzerwa muhuwandu hwe0.1% -0.5% yehuremu hwesimende, inoda kugadziriswa maererano nezvinodiwa chaizvo.

Chenjerera kune nharaunda yekuvaka: Tembiricha uye humidity zvine zvakakosha pakuita kweHPMC, uye chimiro chinofanira kugadziriswa pasi pemamiriro akasiyana-siyana kuti uwane migumisiro yakanakisisa.

Kushandiswa kwehydroxypropyl methylcellulose mudhaka resimende zvinobudirira kuvandudza anti-kupararira kwezvinhu, nekudaro kunatsiridza mashandiro ekuvaka uye kusimba kwenguva refu kwedhaka. Nekutsvagisa kwakadzama pamusoro pemaitiro echiito cheAnxinCel®HPMC uye nekugadzirisa maitiro ekuwedzera, mabhenefiti ayo ekuita anogona kuwedzeredzwa kuti ape mhinduro dzemhando yepamusoro dzezvirongwa zvekuvaka.