Maitiro ekushandisa hydroxypropyl methylcellulose uye matanho ekuzvidzivirira

1. Nhanganyaya yehydroxypropyl methylcellulose

Hydroxypropyl methylcellulose (HPMC)is a non-ionic cellulose ether yakagadzirwa kubva kuzvinhu zvakasikwa zvepolymer kuburikidza nekugadzirisa kemikari. Inoshandiswa zvakanyanya mukuvaka, mishonga, chikafu, cosmetics, cosmetics uye mamwe minda, uye ine akawanda mabasa akadai sekukora, kuchengetedza mvura, kugadzira firimu, uye kunamatira.

2. Nzira yekushandisa sei hydroxypropyl methylcellulose

Kuparara kwemvura inotonhora
AnxinCel®HPMC inogona kuparadzirwa zvakananga mumvura inotonhora, asi nekuda kweiyo hydrophilicity, zviri nyore kugadzira mapundu. Zvinokurudzirwa kumwaya zvishoma nezvishoma HPMC mumvura inotonhora yakamutswa kuti ive nechokwadi chekupararira kweyunifomu uye kudzivirira kusangana.

Kuparara kwemvura inopisa
Mushure me pre-wetting HPMC nemvura inopisa, wedzera mvura inotonhora kuzvimba kuti uite yunifomu mhinduro. Iyi nzira yakakodzera kune yakakwirira-viscosity HPMC.

Dry powder kusanganisa
Usati washandisa HPMC, inogona kusanganiswa zvakaenzana nehumwe hupfu mbishi, uye wozobvongodzwa nekunyungudutswa nemvura.

Indasitiri yekuvaka
Mudhaka uye putty poda, huwandu hwekuwedzera hweHPMC hunowanzo 0.1% ~ 0.5%, iyo inonyanya kushandiswa kuvandudza kuchengetwa kwemvura, kuita kwekuvaka uye anti-sagging performance.

Pharmaceutical industry
HPMC inowanzo shandiswa mukuputira piritsi uye inosimudzira-kuburitsa matrix, uye dosi yayo inofanirwa kugadziridzwa zvinoenderana neiyo chaiyo formula.

Indasitiri yezvokudya
Kana ichishandiswa seyakakora kana emulsifier muchikafu, dosi yacho inofanirwa kuenderana nemaitiro ekuchengetedza chikafu, kazhinji 0.1% ~ 1%.

Coatings
Kana HPMC ichishandiswa mumvura-based coatings, inogona kuvandudza kukora uye dispersibility yejasi uye kudzivirira pigment kunaya.

Cosmetics
HPMC inoshandiswa seyakagadzikana mune zvekuzora kuvandudza kubata uye ductility yechigadzirwa.

3. Kungwarira pakushandisa hydroxypropyl methylcellulose

Dissolution nguva uye tembiricha kutonga
HPMC inotora imwe nguva yekunyungudika, kazhinji maminetsi makumi matatu kusvika maawa maviri. Kunyanya kupisa kana kuderera zvakanyanya kunokanganisa chiyero chekunyungudika, uye tembiricha yakakodzera uye mamiriro ekusimudzira anofanirwa kusarudzwa zvichienderana nemamiriro chaiwo.

Dzivisa agglomeration
Paunenge uchiwedzera HPMC, inofanirwa kuparadzirwa zvishoma nezvishoma uye nekukandwa zvakakwana kudzivirira kusangana. Kana agglomeration ikaitika, inoda kusiiwa iri yoga kwekanguva uye kumutswa mushure mekunge yazvimba zvachose.

Kufurira kwehunyoro hwezvakatipoteredza
HPMC inonzwa nekunyorova uye inonamira kunyura uye kuunganidzwa munzvimbo ine hunyoro hwepamusoro. Nokudaro, kutarisa kunofanira kubhadharwa kune kuoma kwenzvimbo yekuchengetedza uye kuvhara kunofanira kuiswa chisimbiso.

Acid uye alkali kuramba
HPMC haina kugadzikana kune asidhi uye alkalis, asi inogona kudzikisira mune yakasimba asidhi kana alkali nharaunda, zvichikanganisa kushanda kwayo. Naizvozvo, yakanyanyisa pH mamiriro anofanirwa kudzivirirwa zvakanyanya sezvinobvira panguva yekushandiswa. 

Kusarudzwa kwemhando dzakasiyana
HPMC ine mhando dzakasiyana dzemhando (senge yakakwira viscosity, yakaderera viscosity, kukurumidza kupera, nezvimwewo), uye kuita kwavo uye kushandiswa kwakasiyana. Paunosarudza, muenzaniso wakakodzera unofanirwa kusarudzwa maererano nemamiriro chaiwo ekushandiswa (zvakadai sezvigadzirwa zvekuvaka, mishonga yemishonga, nezvimwewo) uye zvinodiwa.

Utsanana uye kuchengeteka
Paunenge uchishandisa AnxinCel®HPMC, zvekudzivirira zvinofanirwa kupfekwa kudzivirira kufemesa huruva.

Kana ichishandiswa muchikafu nemushonga, inofanirwa kutevedzera mirau uye zviyero zveindasitiri yakakodzera.

Kuenderana nezvimwe zvinowedzera

Kana yakasanganiswa nezvimwe zvinhu mufomula, kutarisisa kunofanirwa kubhadharwa kune kuenderana kwayo kudzivirira kunaya, coagulation kana kumwe kukanganisa kwakaipa.

4. Kuchengeta uye kutakura

Storage
HPMCinofanira kuchengetwa munzvimbo inotonhorera, yakaoma, kudzivisa kupisa kwakanyanya uye hunyoro. Zvigadzirwa zvisina kushandiswa zvinoda kuiswa chisimbiso.

Transportation
Panguva yekufambisa, inofanirwa kuchengetedzwa kubva kunaya, unyoro uye tembiricha yakakwira kudzivirira kukanganisa kurongedza.

Hydroxypropyl methylcellulose ikemikari inoshandiswa zvakasiyana-siyana inoda kuparara kwesainzi uye zvine musoro, kuwedzera uye kuchengetedza mukushandisa zvinoshanda. Chenjerera kuti udzivise agglomeration, kudzora dissolution mamiriro, uye sarudza yakakodzera modhi uye dosi zvinoenderana neakasiyana mashandisirwo mamiriro ekuwedzera kuita kwayo. Panguva imwecheteyo, zviyero zveindasitiri zvinofanirwa kuteedzerwa zvakanyanya kuti ive nechokwadi chekushandisa kwakachengeteka uye kwakanaka kweHPMC.