Hydroxypropyl Methylcellulose (HPMC) uyeHydroxyethyl Cellulose (HEC) ese ari maviri anobva ku cellulose, anoshandiswa zvakanyanya muindasitiri, mushonga, zvizorwa uye mamwe minda. Misiyano yavo mikuru inoratidzwa muchimiro chemolecular, solubility maitiro, minda yekushandisa uye zvimwe zvinhu.
1. Chimiro chemolecular
Hydroxypropyl Methylcellulose (HPMC)
HPMC inonyungudika mumvura yakaunzwa nekuunza methyl (-CH3) uye hydroxypropyl (-CH2CHOHCH3) mapoka mu cellulose molecular chain. Kunyanya, iyo molecular chimiro cheHPMC ine maviri anoshanda anotsiva, methyl (-OCH3) uye hydroxypropyl (-OCH2CH (OH) CH3). Kazhinji, muyero wekutanga wemethyl wakakwira, nepo hydroxypropyl inogona kunyatso kuvandudza kunyungudika kweselulosi.
Hydroxyethyl Cellulose (HEC)
HEC inotorwa yakaunzwa nekuunza ethyl (-CH2CH2OH) mapoka mu cellulose molecular chain. Muchigadziro che hydroxyethyl cellulose, rimwe kana mamwe mapoka e-hydroxyl (-OH) e-cellulose anotsiviwa ne ethyl hydroxyl mapoka (-CH2CH2OH). Kusiyana neHPMC, iyo molecular chimiro cheHEC ine chete hydroxyethyl inotsiva uye haina methyl mapoka.
2. Kunyungudika kwemvura
Nekuda kwekusiyana kwemaitiro, kunyungudika kwemvura kweHPMC neHEC kwakasiyana.
HPMC: HPMC ine mvura yakanaka solubility, kunyanya pakusarerekera kana zvishoma alkaline pH values, solubility yayo iri nani pane HEC. Iko kuunzwa kwemethyl uye hydroxypropyl mapoka inosimudzira kunyungudika kwayo uye inogona zvakare kuwedzera viscosity yayo kuburikidza nekudyidzana nemamorekuru emvura.
HEC: HEC inowanzonyungudika mumvura, asi kunyungudika kwayo kunenge kwakashata, kunyanya mumvura inotonhora, uye inowanzoda kunyungudutswa pasi pemamiriro ekupisa kana kuti inoda kuwanda kwepamusoro kuti iwane zvakafanana viscosity madhara. Solubility yayo inoenderana nekusiyana kwemaitiro e cellulose uye hydrophilicity yeboka re hydroxyethyl.
3. Viscosity uye rheological properties
HPMC: Nekuda kwekuvapo kwemapoka maviri akasiyana ehydrophilic (methyl uye hydroxypropyl) mumamorekuru ayo, HPMC ine yakanaka viscosity gadziriso zvivakwa mumvura uye inoshandiswa zvakanyanya mukunamira, machira, detergents, mishonga yekugadzirira uye mimwe minda. Panzvimbo dzakasiyana-siyana, HPMC inogona kupa gadziriso kubva kune yakaderera viscosity kusvika yakakwira viscosity, uye viscosity inonyanya kutarisisa pH shanduko.
HEC: The viscosity yeHEC inogonawo kugadziriswa nekushandura kusungirirwa, asi iyo viscosity kugadzirisa mararamiro iduku kudarika iyo yeHPMC. HEC inonyanya kushandiswa mumamiriro ezvinhu apo pasi kusvika pakati viscosity inodiwa, kunyanya mukuvaka, detergents uye zvigadzirwa zvekuchengeta munhu. Iyo rheological properties yeHEC inenge yakagadzikana, kunyanya munzvimbo dzine acidic kana dzisina kwazvakarerekera, HEC inogona kupa yakagadzikana viscosity.
4. Minda yekushandisa
Hydroxypropyl methylcellulose (HPMC)
Indasitiri yekuvaka: HPMC inowanzoshandiswa musimende dhaka uye machira muindasitiri yekuvaka kuvandudza fluidity, kushanda uye kudzivirira kutsemuka.
Indasitiri yemishonga: Semumiriri wekuburitsa zvinodhaka, HPMC inoshandiswa zvakanyanya muindasitiri yemishonga. Haikwanise kungoshandiswa semugadziri wekugadzira mahwendefa uye capsules, asiwo seanonamatira kubatsira mushonga kusunungurwa zvakaenzana.
Indasitiri yechikafu: HPMC inowanzo shandiswa mukugadzira chikafu seyakagadzika, thickener kana emulsifier kuvandudza magadzirirwo uye kuravira kwechikafu.
Indasitiri yezvekuzora: Seyakakora, HPMC inoshandiswa zvakanyanya muzvigadzirwa zvakaita semafuta, shampoos, uye maconditioner kuwedzera viscosity uye kugadzikana kwezvigadzirwa.
Hydroxyethyl cellulose (HEC)
Indasitiri yekuvaka: HEC inowanzo shandiswa musimende, gypsum, uye mataira anonamira kuvandudza kuyerera uye nguva yekuchengeta yechigadzirwa.
Kuchenesa: HEC inowanzoshandiswa mukuchenesa imba, kuchenesa midziyo uye zvimwe zvigadzirwa kuwedzera viscosity yechigadzirwa uye kugadzirisa maitiro ekuchenesa.
Indasitiri yezvizoro: HEC inoshandiswa zvakanyanya muzvigadzirwa zvekuchengetedza ganda, gels yekugezesa, shampoos, nezvimwewo seyakakora uye inomisa mumiriri kuti ivandudze magadzirirwo uye kugadzikana kwechigadzirwa.
Oiri kudhirowa: HEC inogona zvakare kushandiswa mukuita kubviswa kwemafuta seyakakora mumvura-yakavakirwa kudhiraivha zvinwiwa kubatsira kuwedzera viscosity yemvura uye kunatsiridza dhiri.
5. pH kugadzikana
HPMC: HPMC inonzwa zvakanyanya kune pH shanduko. Pasi pemamiriro e acidic, kunyungudika kweHPMC kunoderera, izvo zvinogona kukanganisa kushanda kwayo. Naizvozvo, inowanzoshandiswa mune isina kwayakarerekera kune zvishoma alkaline nharaunda.
HEC: HEC inoramba yakagadzikana pamusoro pehupamhi pH renji. Iine kusimba kwakasimba kune acidic uye alkaline nharaunda, saka inowanzoshandiswa mukuumbwa kunoda kugadzikana kwakasimba.
HPMCuyeHECinosiyana muchimiro chemolecular, solubility, viscosity kugadzirisa kuita, uye nzvimbo dzekushandisa. HPMC ine mvura yakanaka solubility uye viscosity kugadzirisa kuita, uye inokodzera maapplication anoda yakakwira viscosity kana chaiyo inodzorwa kuburitsa kuita; nepo HEC ine yakanaka pH kugadzikana uye huwandu hwakawanda hwekushandisa, uye yakakodzera kune zviitiko zvinoda yepakati uye yakaderera viscosity uye yakasimba kuchinjika kwezvakatipoteredza. Mumashandisirwo chaiwo, kusarudzwa kwechinhu chipi chinoda kuongororwa zvichienderana nezvinodiwa chaizvo.
Nguva yekutumira: Feb-24-2025