Pane chii pH iri HPMC soluble

Hydroxypropyl methylcellulose (HPMC)i polymer inowanzoshandiswa mumishonga yemishonga, cosmetics, uye zvigadzirwa zvekudya. Kunyungudika kwayo kunoenderana nezvinhu zvakasiyana, kusanganisira pH. Kazhinji, HPMC inonyungudika mune ese aridhi uye alkaline mamiriro, asi kunyungudika kwayo kunogona kusiyanisa zvichienderana nedhigirii rekutsiva (DS) uye huremu hwemamorekuru (MW) epolymer.

Mumamiriro ezvinhu ane acidic, HPMC inowanzoratidza kunyungudika kwakanaka nekuda kweiyo protonation yemapoka ayo ehydroxyl, ayo anosimudzira hydration uye dispersibility. Kunyungudika kweHPMC kunowedzera kuwedzera sezvo pH inodzikira pazasi pKa yayo, iyo iri kutenderera 3.5-4.5 zvichienderana nehuwandu hwekutsiva.

Sezvineiwo, mumamiriro ealkaline, HPMC inogona zvakare kunyungudika, kunyanya pakakwirira pH kukosha. Pa alkaline pH, deprotonation yemapoka e-hydroxyl inoitika, zvichikonzera kuwedzera kunyungudika kuburikidza nehydrogen bonding nemamorekuru emvura.

Nekudaro, zvakakosha kuti uzive kuti iyo pH chaiyo iyo HPMC inonyungudika inogona kusiyana zvichienderana negiredhi reHPMC, dhigirii rekutsiva, uye huremu hwayo hwemamorekuru. Kazhinji, HPMC mamakisi ane madhigirii epamusoro ekutsiva uye epasi mamorekuru uremu anoratidza kunyungudika kuri nani pane yakaderera pH kukosha.

Mukugadzirwa kwemishonga,HPMCinowanzoshandiswa seyaimbova firimu, thickener, kana stabilizer. Hunhu hwayo hwekunyungudika hwakakosha pakudzora maprofile ekuburitswa kwezvinodhaka, viscosity yemagadzirirwo, uye kugadzikana kweemulsions kana kumiswa.

nepo HPMC ichiwanzonyungudika pamusoro pehupamhi pH renji, maitiro ayo ekunyungudika anogona kukwenenzverwa nekugadzirisa pH yemhinduro uye kusarudza giredhi rakakodzera reHPMC zvichibva pane yaunoda application.