1. Nhanganyaya
Hydroxypropyl methylcellulose (HPMC) yakakosha yekugadzira cellulose derivative inoshandiswa zvakanyanya mukuvaka, kugadzirira mishonga, zvekuwedzera zvekudya uye zvekuzora. Kuchengetwa kwayo kwemvura kwakanaka ndechimwe chezvinhu zvakakosha zveHPMC's wide application.
2. Mamiriro uye zvivakwa zveHPMC
2.1 Chimiro chemakemikari
HPMC is a semi-synthetic cellulose ether. Iyo hydroxypropyl uye methyl zvinotsiva mune kemikari chimiro zvinopa iyo yakasarudzika solubility uye colloidal zvimiro. Iyo yakakosha chimiro cheHPMC ine β-D-glucose cheni dze cellulose, umo mamwe mapoka ehydroxyl anotsiviwa ne methyl uye hydroxypropyl mapoka. Chinzvimbo uye dhigirii rekutsiviwa kweaya anotsiva anokanganisa zvakananga kunyungudika, viscosity uye kuchengetwa kwemvura kweHPMC.
2.2 Zvimiro zvemuviri
Kunyungudika kwemvura: HPMC inonyungudika nyore mumvura inotonhora uye inoumba colloidal mhinduro mumvura inopisa.
Kukora chivakwa: Inogona kugadzira viscous mhinduro mumvura uye ine yakanaka thickening maitiro.
Firimu-yekugadzira chivakwa: Inogona kugadzira yakajeka uye elastic firimu.
Suspension: Iyo ine yakanaka kumiswa kuita mumhinduro uye inogona kudzikamisa nyaya yakamiswa.
3. Kuchengetwa kwemvura kweHPMC
3.1 Nzira yekuchengetedza mvura
Kuchengetwa kwemvura kweHPMC kunonyanya kukonzerwa nekudyidzana pakati peiyo hydroxyl nemapoka anotsiva mune ayo mamorekuru chimiro uye mamorekuru emvura. Kunyanya, HPMC inochengeta mvura kuburikidza nenzira dzinotevera:
Hydrogen bonding: Iwo mapoka ehydroxyl ari muHPMC mamorekuru anoumba hydrogen bond nemamorekuru emvura. Simba iri rinogonesa mamorekuru emvura kuti asungirwe zvakasimba akatenderedza HPMC, zvichideredza kubuda kwemvura.
Yakakwira viscosity athari: Iyo yakakwirira viscosity mhinduro yakaumbwa neHPMC mumvura inogona kutadzisa kufamba kwemvura, nekudaro ichidzikisa kurasikirwa kwemvura.
Chimiro chetiweki: Iyo network yakaumbwa neHPMC mumvura inogona kutora uye kuchengetedza mamorekuru emvura, kuitira kuti mvura igovane zvakaenzana mune network chimiro.
Colloid effect: Iyo colloid inoumbwa neHPMC inogona kuvhara mvura mukati mecolloid uye kuwedzera nguva yekuchengetedza mvura.
3.2 Zvinhu zvinokanganisa kuchengetwa kwemvura
Dhigirii rekutsinhanisa: Kuchengetwa kwemvura kweHPMC kunokanganiswa nedhigirii rekutsiva (DS). Iyo yakakwirira dhigirii yekutsiva, iyo yakasimba iyo hydrophilicity yeHPMC uye zvirinani kuita kwayo kuchengetedza mvura.
Huremu hwemamorekuru: Huremu hwepamusoro huremu hunobatsira kuumba yakasimba mamorekuru cheni network, nekudaro inovandudza kuchengetwa kwemvura.
Concentration: Iko kusungirirwa kweHPMC mhinduro kune zvakakosha pakuchengetedza mvura. High-concentration solutions inokwanisa kuumba mamwe ma-viscous solutions uye akanyanya kugadzikana maitirwo emagetsi, nokudaro kuchengetedza mvura yakawanda.
Tembiricha: Kuchengetwa kwemvura kweHPMC kunosiyana nekupisa. Kana kutonhora kuchikwira, viscosity yeHPMC solution inoderera, zvichiita kuti kuderera kwekuchengetedza mvura.
4. Kushandiswa kweHPMC munzvimbo dzakasiyana
4.1 Zvishandiso zvekuvaka
Muzvivakwa zvekuvaka, HPMC inoshandiswa sechinhu chinochengeta mvura semende uye gypsum-based products. Mabasa ayo makuru anosanganisira:
Kuvandudza mashandiro ekuvaka: Nekuchengetedza hunyoro hwakakodzera, nguva yakavhurika yesimende uye gypsum inowedzerwa, zvichiita kuti basa rekuvaka rive rakapfava.
Deredza kuputika: Kuchengetedza mvura kwakanaka kunobatsira kuderedza kuputika kunogadzirwa panguva yekuomeswa uye kunatsiridza kusimba uye kusimba kwechinhu chekupedzisira.
Kuvandudza chisungo chesimba: Mumataira anonamira, HPMC inogona kuwedzera bond simba uye kuwedzera chisungo mhedzisiro.
4.2 Kugadzirira kwemishonga
Mukugadzirira kwemishonga, kuchengetwa kwemvura kweHPMC kunoita basa rakakosha mukuburitswa nekugadzikana kwemishonga:
Sustained-release preparations: HPMC inogona kushandiswa seyakasimba-kuburitswa matrix yemishonga kuti iwane kuburitswa kwakasimba kwezvinodhaka nekudzora kupinza kwemvura uye kuparara kwezvinodhaka.
Makobvu nemabhainda: Mumishonga yemvura uye mahwendefa, HPMC inoita seyakakora uye bhainda kuchengetedza kugadzikana uye kuenderana kwezvinodhaka.
4.3 Zvokudya zvinowedzera
Muindasitiri yezvekudya, HPMC inoita seyakakora uye inodzikamisa, uye kuchengetedza kwayo mvura kunoshandiswa kune:
Kuvandudza kuravira: Kuburikidza nekuchengetedza mvura, HPMC inogona kuvandudza magadzirirwo uye kuravira kwechikafu, ichiita kuti ive yakawedzera mafuta uye inonaka.
Kuwedzera hupenyu hwesherufu: Kuburikidza nekuchengetedza mvura, HPMC inogona kudzivirira kurasikirwa kwemvura panguva yekuchengetedza, nekudaro ichiwedzera hupenyu hwesherufu.
4.4 Zvizoro
Muzvizoro, kuchengetwa kwemvura kweHPMC kunoshandiswa ku:
Moisturizing mhedzisiro: Seyakanyorovesa, HPMC inogona kubatsira kukiya munyoro pamusoro peganda uye kupa kwenguva yakareba moisturizing mhedzisiro.
Kudzikamisa kumiswa: Mune emulsions uye kumiswa, HPMC inodzikamisa chigadzirwa uye inodzivirira stratification uye sedimentation.
Kuchengetwa kwemvura kweHPMC kunoita kuti ive yakakosha inoshanda zvinhu muminda yakawanda. Inochengeta mvura uye inoderedza kubuda kwemvura kuburikidza nehydrogen bonding, yakakwirira viscosity mhedzisiro, network chimiro uye colloid mhedzisiro. Kuchengetwa kwemvura kunokanganiswa nedhigirii rekutsiva, huremu hwemamorekuru, kutarisisa uye tembiricha, izvo zvinotarisa kuita kweHPMC mune chaiyo application. Zvingave mune zvekuvaka, kugadzirira kwemishonga, zvekuwedzera zvekudya kana zvizorwa, kuchengetwa kwemvura kweHPMC kunoita basa rakakosha mukuvandudza kunaka uye kuita kwechigadzirwa.
Nguva yekutumira: Jun-26-2024