Igiciro cyihariye cy'Ubushinwa Hypromellose HPMC Ingana na Methocel ku biribwa na farumasi
Hamwe n'amahame y'ubucuruzi "ashingiye ku mukiriya", uburyo buhamye bwo gucunga neza, ibikoresho bigezweho byo gukora ndetse n'abakozi bakomeye mu bushakashatsi no mu iterambere, duhora dutanga ibicuruzwa n'ibisubizo byiza, ibicuruzwa na serivisi byiza ndetse n'ibiciro bikomeye ku giciro cyihariye mu Bushinwa Hypromellose HPMC Ingana na Methocel ku biribwa na farumasi, Dufite ubwoko bwinshi, bwiza, ibiciro biringaniye n'imiterere myiza, ibicuruzwa byacu bikoreshwa cyane muri uru rwego no mu zindi nganda.
Hamwe n'amahame y'ubucuruzi "ashingiye ku mukiriya", uburyo bwiza bwo gucunga neza, ibikoresho bigezweho byo gukora ndetse n'abakozi bakomeye bo mu bushakashatsi no mu iterambere, duhora dutanga ibicuruzwa n'ibisubizo byiza, ibicuruzwa na serivisi byiza ndetse n'ibiciro bikomeye kuriHPMC y'Ubushinwa, selulose ya hydroxypropyl methylPerezida n'abanyamuryango bose b'ikigo bifuza gutanga ibisubizo na serivisi by'abahanga ku bakiriya babo, kandi bakirana ikaze kandi bagakorana n'abakiriya bose kavukire n'abanyamahanga kugira ngo hazagire ahazaza heza.
Ibisobanuro by'igicuruzwa
NOMERO Y'IBIHE: 9004-65-3
Formula ya Molecular
Hypromellose (Hydroxypropylmethylcellulose: HPMC) ubwoko bw'isimbuza 2910, 2906, 2208 (USP)
Imiterere Ifatika
- Ifu y'umweru cyangwa umuhondo wera
- Bishobora gushonga mu buryo bw'umwimerere cyangwa amazi avanze
- Gukora firime ibonerana iyo uvanyeho umuti uvanze n'amazi
- Nta mpungenge z'imiti ziterwa n'umuti bitewe n'ubushobozi bwawo butari ioni
- Uburemere bwa molekile: 10.000 ~ 1.000.000
- Agace ka gel: 40 ~ 90℃
- Aho gucana byikora: 360℃
Hydroxypropyl Methylcellulose (HPMC) Farumasi yo mu bwoko bwa Hypromellose ni inyunganizi n'inyongeramusaruro by'imiti, ishobora gukoreshwa nk'inyunganizi, igabanya ubushyuhe, igabanya ubushyuhe n'itunganya filime.
KimaCellulose ether igizwe na methyl cellulose (USP, EP, BP, CP) n'ubwoko butatu bw'isimbuzaselulose ya hydroxypropyl methyl(hypromellose USP, EP, BP, CP) buri kimwe kiboneka mu byiciro bitandukanye mu bushyuhe. Ibicuruzwa bya HPMC bikomoka ku ipamba ryatunganyijwe karemano n'ibiti, byujuje ibisabwa byose bya USP, EP, BP, hamwe n'ibyemezo bya Kosher na Halal.
Mu gikorwa cyo gukora, ipamba karemano isukuye cyane iterwa na methyl chloride cyangwa ivanze na methyl chloride na propylene oxide kugira ngo habeho ether ya cellulose ishonga mu mazi kandi idashonga. Nta mutungo w’inyamaswa ukoreshwa mu gukora HPMC. HPMC ishobora gukoreshwa nk'igikoresho cyo gufata ubwoko bukomeye bw’ibipimo nk'ibinini n'udukoko. Ikora kandi imirimo itandukanye, urugero nko kongera ubushobozi bwo kubika amazi, kubyibuha, gukora nk'ingufu zo kurinda bitewe n'imikorere yayo, gukomeza kurekura no gukora filime.
KimaCell HPMC itanga imirimo itandukanye nko kubika amazi, kurinda koloyide, gukora ku buso, no kurekura burundu. Ni ikintu kidakoresha ioni kirwanya umunyu kandi gihoraho mu rugero rwa pH. Ikoreshwa rya HPMC risanzwe rituma ikoreshwa mu buryo bufatika nk'ibinini n'udukoko cyangwa ikintu kibyimbisha mu gukoresha amazi.
Pharma HPMC iza mu bwoko butandukanye bwa viscosity kuva kuri 3 kugeza kuri 200.000 cps, kandi ishobora gukoreshwa cyane mu gusiga ibinini, gusya, gufunga, gukurura, gusiga neza no gukora capsule ya HPMC y'imboga.
Ibisobanuro by'imiti
| Hypromellose Ibisobanuro | 60E (2910) | 65F (2906) | 75K (2208) |
| Ubushyuhe bwa gel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Ubushyuhe (cps, 2% Igisubizo) | 3, 5, 6, 15, 50, 100, 400, 4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Ingano y'ibicuruzwa
| Hypromellose Ibisobanuro | 60E (2910) | 65F (2906) | 75K (2208) |
| Ubushyuhe bwa gel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Ubushyuhe (cps, 2% Igisubizo) | 3, 5, 6, 15, 50, 100, 400, 4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Porogaramu
HPMC yo mu bwoko bwa Pharma Grade ituma habaho imiti ikoreshwa mu buryo bugenzurwa, ikoresheje uburyo bwo gufata ibinini bukoreshwa cyane. Pharma Grade itanga ifu nziza, ihuye, kandi irakomera, bigatuma ikoreshwa mu buryo butaziguye.
| Gusaba imiti igabanya ubukana bw'imiti | HPMC yo mu rwego rwa farumasi | Igipimo |
| Ifu yo koga mu bwinshi | 75K4000,75K100000 | 3-30% |
| Amavuta yo kwisiga, Gel | 60E4000,75K4000 | 1-5% |
| Gutegura amaso | 60E4000 | 01.-0.5% |
| Amavuta yo mu maso | 60E4000 | 0.1-0.5% |
| Umukozi Ushinzwe Guhagarika | 60E4000, 75K4000 | 1-2% |
| Antacids | 60E4000, 75K4000 | 1-2% |
| Ibinini byo kubikamo ibinini | 60E5, 60E15 | 0.5-5% |
| Ingano y'amazi yo mu bwoko bwa "Convention Wet Granulation" | 60E5, 60E15 | 2-6% |
| Udupira two gupfuka ibinini | 60E5, 60E15 | 0.5-5% |
| Matrix yo Gusohora Igenzura | 75K100000,75K15000 | 20-55% |
Ibiranga n'Ibyiza
- Kunoza imiterere y'imikoreshereze y'ibicuruzwa
- Bigabanya igihe cyo gutunganya
- Imiterere isa kandi ihamye yo gusenyuka
- Binoza uburyo ibikubiye mu nkuru bihurirana
- Bigabanya ikiguzi cyo gukora
- Igumana imbaraga zo gukurura nyuma yo gukurura kabiri (gukurura imigozi)
Gupfunyika
Igikoresho gisanzwe cyo gupakira ni 25kg/ingoma
20'FCL: toni 9 zifite pallets; toni 10 zitarashyirwa pallets.
40'FCL: toni 18 zifite pallets; toni 20 zitarashyirwamo pallets.
Hamwe n'amahame y'ubucuruzi "ashingiye ku mukiriya", uburyo buhamye bwo gucunga neza, ibikoresho bigezweho byo gukora ndetse n'abakozi bakomeye mu bushakashatsi no mu iterambere, duhora dutanga ibicuruzwa n'ibisubizo byiza, ibicuruzwa na serivisi byiza ndetse n'ibiciro bikomeye ku giciro cyihariye mu Bushinwa Hypromellose HPMC Ingana na Methocel ku biribwa na farumasi, Dufite ubwoko bwinshi, bwiza, ibiciro biringaniye n'imiterere myiza, ibicuruzwa byacu bikoreshwa cyane muri uru rwego no mu zindi nganda.
Igiciro cyihariye ku Bushinwa HPMC, Hydroxypropyl Methyl Cellulose, Perezida n'abanyamuryango bose b'ikigo bifuza gutanga ibisubizo na serivisi by'abahanga ku bakiriya babo kandi bakirana by'ukuri kandi bagakorana n'abakiriya bose kavukire n'abanyamahanga kugira ngo hazagire ahazaza heza.
