Numero yuruhererekane ya Hydroxypropyl Methylcellulose niyihe?

Hydroxypropyl Methylcellulose (HPMC)ni uburyo bwahinduwe bwa selile ya selile ikoreshwa cyane mubikorwa bitandukanye nka farumasi, umusaruro wibiribwa, nubwubatsi. Nibintu byinshi bitandukanye, bikunze gukoreshwa nkibibyimbye, bihuza, bikora firime, na stabilisateur. Ariko, ntabwo ifite "numero yuruhererekane" yihariye mubisanzwe, nkibicuruzwa cyangwa umubare wigice ushobora gusanga mubindi bikorwa. Ahubwo, HPMC igaragazwa nimiterere yimiti hamwe nibintu byinshi biranga, nkurwego rwo gusimbuza no kwiyegeranya.

Amakuru Rusange Yerekeye Hydroxypropyl Methylcellulose (HPMC)

Imiterere yimiti: HPMC ikorwa muburyo bwo guhindura selile ikoresheje insimburangingo ya hydroxyl (-OH) hamwe na hydroxypropyl na methyl. Gusimbuza guhindura imiterere ya selile, bigatuma irushaho gushonga mumazi no kuyiha imiterere yihariye nko kunoza ubushobozi bwo gukora firime, ubushobozi bwo guhuza, hamwe nubushobozi bwo kugumana ubushuhe.

Ibiranga Rusange no Kwita Izina

Kumenyekanisha Hydroxypropyl Methylcellulose mubusanzwe bishingiye kumasezerano atandukanye yo kwita amazina asobanura imiterere yimiti nimiterere:

Umubare CAS:

Serivisi ishinzwe imiti (CAS) itanga ikiranga kidasanzwe kuri buri kintu cyimiti. Umubare CAS kuri Hydroxypropyl Methylcellulose ni 9004-65-3. Numubare usanzwe ukoreshwa naba chimiste, abatanga isoko, ninzego zishinzwe kugenzura ibintu.

InChI na SMILES Kode:

InChI (International Chemical Identifier) ​​nubundi buryo bwo kwerekana imiterere yimiti yibintu. HPMC yaba ifite umugozi muremure wa InChI ugereranya imiterere ya molekuline muburyo busanzwe.

SMILES (Byoroheje Molecular Yinjiza Umurongo Winjira Sisitemu) nubundi buryo bukoreshwa muguhagararira molekile muburyo bwinyandiko. HPMC ifite kandi code ya SMILES ihuye, nubwo yaba igoye cyane kubera imiterere nini kandi ihindagurika yimiterere yayo.

Ibisobanuro ku bicuruzwa:

Ku isoko ryubucuruzi, HPMC ikunze kugaragazwa numubare wibicuruzwa, bishobora gutandukana nababikora. Kurugero, utanga isoko ashobora kugira amanota nka HPMC K4M cyangwa HPMC E15. Ibiranga akenshi bivuga ubwiza bwa polymer mugisubizo, bigenwa nurwego rwa methylation na hydroxypropylation kimwe nuburemere bwa molekile.

Ibyiciro bisanzwe bya Hydroxypropyl Methylcellulose (HPMC)

Ibiranga Hydroxypropyl Methylcellulose biratandukanye bitewe nurwego rwo gusimbuza amatsinda ya methyl na hydroxypropyl, hamwe nuburemere bwa molekile. Ihindagurika ryerekana ubwiza bwa HPMC no gukomera mumazi, ibyo nabyo bigira ingaruka mubikorwa byayo mubikorwa bitandukanye.

Hasi nimbonerahamwe yerekana amanota atandukanye ya Hydroxypropyl Methylcellulose:

Ibisobanuro birambuye hamwe nibyiza bya HPMC

Imiterere yumubiri ya Hydroxypropyl Methylcellulose iterwa ahanini nuburyo bwo gusimbuza amatsinda ya hydroxyl muri molekile ya selile. Dore ibintu by'ingenzi:

Impamyabumenyi yo gusimburwa (DS):

Ibi bivuga umubare wamatsinda ya hydroxyl muri selile yasimbujwe na methyl cyangwa hydroxypropyl. Urwego rwo gusimbuza rugira ingaruka ku gukomera kwa HPMC mumazi, ububobere bwayo, hamwe nubushobozi bwo gukora firime. Ubusanzwe DS ya HPMC iri hagati ya 1.4 na 2.2, ukurikije amanota.

Viscosity:

Amanota ya HPMC ashyirwa mubyiciro ukurikije ubwiza bwabyo iyo bishonge mumazi. Iyo uburemere bwa molekile buringaniye hamwe nurwego rwo gusimburwa, niko ubwiza bwiyongera. Kurugero, HPMC K100M (hamwe nurwego rwo hejuru rwijimye) ikoreshwa kenshi mugukoresha imiti igenzurwa-irekurwa, mugihe amanota yo hasi yubukonje nka HPMC K4M akoreshwa mububiko bwa tableti no gukoresha ibiryo.

Amazi meza:

HPMC irashobora gushonga mumazi kandi ikora ibintu bisa na gel iyo bishonge, ariko ubushyuhe na pH birashobora kugira ingaruka kubishobora. Kurugero, mumazi akonje, irashonga vuba, ariko imbaraga zayo zirashobora kugabanuka mumazi ashyushye, cyane cyane mukwiyongera cyane.

Ubushobozi bwo Gukora Filime:

Kimwe mu bintu by'ingenzi biranga Hydroxypropyl Methylcellulose nubushobozi bwayo bwo gukora firime yoroheje. Uyu mutungo utuma ukoreshwa muburyo bwa tablet, aho utanga ubuso bworoshye, bugenzurwa-kurekura. Ni ingirakamaro kandi mu nganda zibiribwa kunoza imiterere nubuzima bwiza.

Gelation:

Mubushuhe bumwe nubushuhe, HPMC irashobora gukora geles. Uyu mutungo ufite akamaro muburyo bwo gufata imiti, aho bikoreshwa mugukora sisitemu igenzurwa-irekura.

Porogaramu ya Hydroxypropyl Methylcellulose

Inganda zimiti:

HPMC ikoreshwa nka binder muburyo bwa tablet, cyane cyane mugusohora-kurekura no kugenzura-kurekura. Ikora kandi nk'igikoresho cyo gutwikira ibinini na capsules kugirango igenzure irekurwa ryibintu bikora. Ubushobozi bwayo bwo gukora firime zihamye hamwe na geles nibyiza muburyo bwo gutanga ibiyobyabwenge.

Inganda zikora ibiribwa

Mu nganda zibiribwa, HPMC ikoreshwa nkibintu byongera umubyimba, emulisiferi, na stabilisateur mubicuruzwa bitandukanye, birimo isosi, imyambarire, nibicuruzwa bitetse. Ifasha kunoza imiterere no kwagura igihe cyo kugabanya kugabanya ubushuhe.

Amavuta yo kwisiga no kwita ku muntu:

HPMC ikoreshwa cyane mu kwisiga, aho ikora nk'ibyimbye kandi bigahindura amavuta, amavuta yo kwisiga, shampo, nibindi bicuruzwa byita ku muntu. Ubushobozi bwayo bwo gukora imiterere ya gel ningirakamaro cyane muribi bikorwa.

Inganda zubaka:

Mu nganda zubaka, cyane cyane muri sima na pompa, HPMC ikoreshwa nkibikoresho bigumana amazi. Ifasha kunoza imikorere no kuzamura imiterere yibikoresho.

Ibindi Porogaramu:

HPMC ikoreshwa kandi mu nganda z’imyenda, impapuro, ndetse no mu gukora firime zibora.

Hydroxypropyl Methylcellulose (HPMC)ni ibice byinshi bihujwe bikoreshwa mu nganda nyinshi bitewe nuburyo bwihariye nkubushobozi bwo gukora firime, ubushobozi bwo kubyimba, no kubika amazi. Mugihe idafite "numero yuruhererekane" muburyo busanzwe, igaragazwa nibiranga imiti nka numero yayo ya CAS (9004-65-3) hamwe n amanota yihariye yibicuruzwa (urugero, HPMC K100M, HPMC E4M). Ibyiciro bitandukanye by'amanota ya HPMC aboneka byerekana neza ko byakoreshwa mubice bitandukanye, kuva imiti kugeza ibiryo, amavuta yo kwisiga, nubwubatsi.