Icyitegererezo cy'Ubwubatsi HPMC-Igiciro gito cyane Ubushinwa Ubwubatsi bw'imiti igabanya ubukana Hydroxypropyl Methyl Cellulose HPMC
Icyo dukora cyose gikunze kuba gifitanye isano n'amahame yacu. "Abakiriya ba mbere, twishingikirize ku ikubitiro, dushyira imbere ibipfunyika by'ibiribwa no kurengera ibidukikije kugira ngo tubone HPMC y'Ubwubatsi - Igiciro gito cyane. Ubushinwa bw'Ubwubatsi bw'Ibinyabutabire Hydroxypropyl Methyl Cellulose HPMC, Ibicuruzwa byacu bigenzurwa neza mbere yo koherezwa mu mahanga, bityo tukagira izina ryiza ku isi yose. Twifuza ko twagirana ubufatanye namwe mu gihe kizaza.
Icyo dukora cyose gifitanye isano n'amahame yacu. "Umukiriya abanza, shingira ku ikubitiro, wibanda ku gupfunyika ibiribwa no kurengera ibidukikije.HPMC y'Ubushinwa, HPMC y'ubwubatsi, Ni abanyamideli bakomeye kandi bateza imbere ibikorwa byabo ku isi yose. Ntibigera bibura imirimo ikomeye mu gihe gito, ni ngombwa kuri wowe ubwawe ufite ireme ryiza cyane. Tuyobowe n'ihame rya "Ubushishozi, Ingufu, Ubumwe n'Udushya. ikigo. Gikora ibishoboka byose kugira ngo cyagure ubucuruzi bwacyo mpuzamahanga, kizamura ikigo cyacyo, gikomeze kandi kizamure urwego rwacyo rwo kohereza ibicuruzwa mu mahanga. Twizeye ko dushobora kugira amahirwe meza kandi ko tuzakwirakwira ku isi yose mu myaka iri imbere.
Ibisobanuro by'igicuruzwa
Hydroxypropyl Methyl Cellulose (HPMC)
Formula ya Molecular
Hypromellose (Hydroxypropylmethylcellulose: HPMC) ubwoko bw'isimbuza 2910, 2906, 2208 (USP)
Imiterere Ifatika
- Ifu y'umweru cyangwa umuhondo wera
- Bishobora gushonga mu buryo bw'umwimerere cyangwa amazi avanze
- Gukora firime ibonerana iyo uvanyeho umuti uvanze n'amazi
- Nta mpungenge z'imiti ziterwa n'umuti bitewe n'ubushobozi bwawo butari ioni
- Uburemere bwa molekile: 10.000 ~ 1.000.000
- Agace ka gel: 40 ~ 90℃
- Aho gucana byikora: 360℃
Hydroxypropyl Methylcellulose (HPMC) Farumasi yo mu bwoko bwa Hypromellose ni inyunganizi n'inyongeramusaruro by'imiti, ishobora gukoreshwa nk'inyunganizi, igabanya ubushyuhe, igabanya ubushyuhe n'itunganya filime.
QualiCell Cellulose ether igizwe na methyl cellulose (USP, EP, BP, CP) n'ubwoko butatu bwa hydroxypropyl methyl cellulose (hypromellose USP, EP, BP, CP) buri bwoko buboneka mu byiciro bitandukanye mu buryo bw'ubushyuhe. Ibicuruzwa bya HPMC bikomoka ku ipamba ryatunganyijwe karemano n'ibiti, byujuje ibisabwa byose bya USP, EP, BP, hamwe n'ibyemezo bya Kosher na Halal.
Mu gikorwa cyo gukora, ipamba karemano isukuye cyane iterwa na methyl chloride cyangwa ivanze na methyl chloride na propylene oxide kugira ngo habeho ether ya cellulose ishonga mu mazi kandi idashonga. Nta mutungo w’inyamaswa ukoreshwa mu gukora HPMC. HPMC ishobora gukoreshwa nk'igikoresho cyo gufata ubwoko bukomeye bw’ibipimo nk'ibinini n'udukoko. Ikora kandi imirimo itandukanye, urugero nko kongera ubushobozi bwo kubika amazi, kubyibuha, gukora nk'ingufu zo kurinda bitewe n'imikorere yayo, gukomeza kurekura no gukora filime.
QualiCell HPMC itanga imirimo itandukanye nko kubika amazi, kurinda koloyide, gukora ku buso, no kurekura burundu. Ni ikintu kidakoresha ioni kirwanya umunyu kandi gihoraho mu rugero rwa pH. Ikoreshwa rya HPMC risanzwe rihuza ubwoko bukomeye bw'ibipimo nk'ibinini n'udukoko cyangwa ikintu kibyimbisha mu gukoresha amazi.
Pharma HPMC iza mu bwoko butandukanye bwa viscosity kuva kuri 3 kugeza kuri 200.000 cps, kandi ishobora gukoreshwa cyane mu gusiga ibinini, gusya, gufunga, gukurura, gusiga neza no gukora capsule ya HPMC y'imboga.
Ibisobanuro by'imiti
| Hypromellose Ibisobanuro | 60E (2910) | 65F (2906) | 75K (2208) |
| Ubushyuhe bwa gel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Ubushyuhe (cps, 2% Igisubizo) | 3, 5, 6, 15, 50, 100, 400, 4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Ingano y'ibicuruzwa
| Hypromellose Ibisobanuro | 60E (2910) | 65F (2906) | 75K (2208) |
| Ubushyuhe bwa gel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Ubushyuhe (cps, 2% Igisubizo) | 3, 5, 6, 15, 50, 100, 400, 4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Porogaramu
HPMC yo mu bwoko bwa Pharma Grade ituma habaho imiti ikoreshwa mu buryo bugenzurwa, ikoresheje uburyo bwo gufata ibinini bukoreshwa cyane. Pharma Grade itanga ifu nziza, ihuye, kandi irakomera, bigatuma ikoreshwa mu buryo butaziguye.
| Gusaba imiti igabanya ubukana bw'imiti | HPMC yo mu rwego rwa farumasi | Igipimo |
| Ifu yo koga mu bwinshi | 75K4000,75K100000 | 3-30% |
| Amavuta yo kwisiga, Gel | 60E4000,75K4000 | 1-5% |
| Gutegura amaso | 60E4000 | 01.-0.5% |
| Amavuta yo mu maso | 60E4000 | 0.1-0.5% |
| Umukozi Ushinzwe Guhagarika | 60E4000, 75K4000 | 1-2% |
| Antacids | 60E4000, 75K4000 | 1-2% |
| Ibinini byo kubikamo ibinini | 60E5, 60E15 | 0.5-5% |
| Ingano y'amazi yo mu bwoko bwa "Convention Wet Granulation" | 60E5, 60E15 | 2-6% |
| Udupira two gupfuka ibinini | 60E5, 60E15 | 0.5-5% |
| Matrix yo Gusohora Igenzura | 75K100000,75K15000 | 20-55% |
Ibiranga n'Ibyiza
- Kunoza imiterere y'imikoreshereze y'ibicuruzwa
- Bigabanya igihe cyo gutunganya
- Imiterere isa kandi ihamye yo gusenyuka
- Binoza uburyo ibikubiye mu nkuru bihurirana
- Bigabanya ikiguzi cyo gukora
- Igumana imbaraga zo gukurura nyuma yo gukurura kabiri (gukurura imigozi)
Gupfunyika
Igikoresho gisanzwe cyo gupakira ni 25kg/ingoma
20'FCL: toni 9 zifite pallets; toni 10 zitarashyirwa pallets.
40'FCL: toni 18 zifite pallets; toni 20 zitarashyirwamo pallets.
Icyo dukora cyose gikunze kuba gifitanye isano n'amahame yacu. "Abakiriya ba mbere, shingira ku ikubitiro, shyira imbaraga mu gupfunyika ibiribwa no kurengera ibidukikije ku giciro gito. Ubushinwa bw'ubwubatsi bw'imiti igabanya ubukana bwa Hydroxypropyl Methyl Cellulose HPMC, Ibicuruzwa byacu bigenzurwa neza mbere yo kohereza mu mahanga, bityo tukagira izina ryiza ku isi yose. Twifuza ko twagirana ubufatanye namwe mu gihe kiri imbere.
Igiciro kigabanuka cyane mu Bushinwa HPMC,HPMC y'ubwubatsi, Ni abanyamideli bakomeye kandi bateza imbere ibikorwa byabo ku isi yose. Ntibigera bibura imirimo ikomeye mu gihe gito, ni ngombwa kuri wowe ubwawe ufite ireme ryiza cyane. Tuyobowe n'ihame rya "Ubushishozi, Ingufu, Ubumwe n'Udushya. ikigo. Gikora ibishoboka byose kugira ngo cyagure ubucuruzi bwacyo mpuzamahanga, kizamura ikigo cyacyo, gikomeze kandi kizamure urwego rwacyo rwo kohereza ibicuruzwa mu mahanga. Twizeye ko dushobora kugira amahirwe meza kandi ko tuzakwirakwira ku isi yose mu myaka iri imbere.
