Kodi hydroxypropyl methylcellulose aqueous solution ndi chiyani?

Hydroxypropyl methylcellulose (HPMC)ndi polima zosungunuka m'madzi zomwe zimagwiritsidwa ntchito kwambiri muzamankhwala, zomangamanga, chakudya, zodzoladzola ndi zina. Katundu wake mamasukidwe akayendedwe ndi gawo lofunika kuyeza khalidwe lake rheological pansi madera osiyanasiyana. Kumvetsetsa katundu wa viscosity wa HPMC amadzimadzi njira kumatithandiza kumvetsa bwino khalidwe lake ndi ntchito zosiyanasiyana ntchito.

1. Kapangidwe ka mankhwala ndi katundu wa HPMC

HPMC imapezeka ndi kusintha kwa mankhwala a cellulose achilengedwe, makamaka opangidwa ndi hydroxypropylation ndi methylation ya ma cellulose. Mu mankhwala a HPMC, kukhazikitsidwa kwa magulu a methyl (-OCH₃) ndi hydroxypropyl (-OCH₂CHOHCH₃) kumapangitsa kuti madzi asasungunuke ndipo ali ndi mphamvu yabwino yosinthira viscosity. The mamasukidwe akayendedwe amadzimadzi njira yake amadzimadzi pa ndende zosiyanasiyana ndi kutentha amakhudzidwa ndi zinthu zambiri monga molecular kulemera, mlingo wa m'malo, ndende yankho, etc.

2. Ubale pakati pa mamasukidwe akayendedwe ndi ndende

The mamasukidwe akayendedwe a AnxinCel®HPMC amadzimadzi njira zambiri amawonjezeka ndi kuchuluka ndende. Izi ndichifukwa choti m'malo okwera kwambiri, kuyanjana pakati pa mamolekyu kumachulukira, zomwe zimapangitsa kukana kwamadzi. Komabe, kusungunuka ndi kukhuthala kwa HPMC m'madzi kumakhudzidwanso ndi kulemera kwa maselo. HPMC yokhala ndi kulemera kwakukulu kwa maselo nthawi zambiri imawonetsa kukhuthala kwakukulu, pomwe kulemera kwa maselo kumakhala kochepa.

Pazigawo zotsika: Yankho la HPMC limawonetsa kukhuthala kocheperako pamagawo otsika (monga pansi pa 0.5%). Panthawiyi, mgwirizano pakati pa mamolekyu ndi wofooka ndipo fluidity ndi yabwino. Nthawi zambiri amagwiritsidwa ntchito ngati zokutira ndi kumasulidwa kwamankhwala kosalekeza.

Pazowonjezereka: Pazowonjezereka (monga 2% kapena kupitilira apo), kukhuthala kwa HPMC yamadzimadzi kumawonjezeka kwambiri, kuwonetsa katundu wofanana ndi mayankho a colloidal. Panthawiyi, madzi amadzimadzi amadzimadzi amatha kukana kwambiri.

3. Ubale pakati pa mamasukidwe akayendedwe ndi kutentha

The mamasukidwe akayendedwe a HPMC amadzimadzi njira kwambiri tcheru kutentha. Pamene kutentha kumawonjezeka, kuyenda pakati pa mamolekyu amadzi kumawonjezeka, ndipo kuyanjana pakati pa mamolekyu a HPMC kumakhala kofooka, zomwe zimapangitsa kuchepa kwa mamasukidwe akayendedwe. Chikhalidwe ichi chimapangitsa kugwiritsa ntchito HPMC pa kutentha kosiyana kusonyeza kusintha kwakukulu. Mwachitsanzo, pansi pa kutentha kwakukulu, kukhuthala kwa HPMC nthawi zambiri kumachepa, komwe kumakhala kofunikira kwambiri pakupanga mankhwala, makamaka mu mawonekedwe a mankhwala otulutsidwa, kumene kusintha kwa kutentha kungakhudze kukhazikika ndi zotsatira za yankho.

4. Zotsatira za pH pa Viscosity

Kukhuthala kwa HPMC yankho lamadzimadzi kumatha kukhudzidwanso ndi pH ya yankho. Ngakhale HPMC ndi chinthu chosakhala ndi ionic, hydrophilicity ndi mamasukidwe ake amakhudzidwa makamaka ndi kapangidwe ka maselo ndi chilengedwe. Komabe, pansi pa zinthu za acidic kwambiri kapena zamchere, kusungunuka ndi kapangidwe ka maselo a HPMC kungasinthe, motero kumakhudza kukhuthala. Mwachitsanzo, pansi pa zinthu za acidic, kusungunuka kwa HPMC kumatha kufooka pang'ono, zomwe zimapangitsa kukhuthala kwamphamvu; pamene pansi pa zinthu zamchere, ndi hydrolysis ena HPMC kungachititse kuti maselo kulemera kuchepa, potero kuchepetsa mamasukidwe akayendedwe ake.

5. Kulemera kwa mamolekyu ndi ma viscosity

Kulemera kwa maselo ndi chimodzi mwazinthu zofunika zomwe zimakhudza kukhuthala kwa HPMC yamadzimadzi. Kulemera kwa mamolekyulu kumawonjezera kutsekeka ndi kulumikizana pakati pa mamolekyu, zomwe zimapangitsa kuti kukhuthala kuchuluke. Kulemera kwa molekyulu ya AnxinCel®HPMC ili ndi kusungunuka kwabwinoko m'madzi komanso kutsika kukhuthala. Zofunikira zosiyanasiyana zogwiritsira ntchito nthawi zambiri zimafuna kusankha kwa HPMC yokhala ndi masikelo osiyanasiyana a maselo. Mwachitsanzo, mu zokutira ndi zomatira, mkulu maselo kulemera HPMC zambiri amasankhidwa bwino adhesion ndi fluidity; pamene mukukonzekera mankhwala, otsika maselo kulemera HPMC angagwiritsidwe ntchito kulamulira mlingo kumasulidwa kwa mankhwala.

6. Ubale pakati pa shear rate ndi mamasukidwe akayendedwe

Kukhuthala kwa HPMC yamadzimadzi amadzimadzi nthawi zambiri kumasintha ndi kumeta ubweya wa ubweya, kusonyeza khalidwe la pseudoplastic rheological. Pseudoplastic fluid ndi madzimadzi omwe kukhuthala kwake kumachepa pang'onopang'ono ndi kuwonjezeka kwa kumeta ubweya. Khalidweli limathandizira yankho la HPMC kuti likhalebe ndi kukhuthala kwakukulu pamlingo wochepa wometa ubweya likagwiritsidwa ntchito, ndikuwonjezera madzimadzi pamlingo wokwezeka kwambiri. Mwachitsanzo, m'makampani opangira zovala, njira ya HPMC nthawi zambiri imayenera kusonyeza kukhuthala kwapamwamba pamtunda wochepetsetsa pamene ikugwiritsidwa ntchito kuti iwonetsetse kuti kumamatira ndi kusakaniza kwazitsulo, pamene panthawi yomanga, ndikofunikira kuonjezera kumeta ubweya kuti apange madzi ambiri.

7. Kugwiritsa ntchito ndi kukhuthala kwa mawonekedwe a HPMC

Makhalidwe a mamasukidwe akayendedwe aMtengo wa HPMCkupanga kuti igwiritsidwe ntchito kwambiri m'magawo ambiri. Mwachitsanzo, m'makampani opanga mankhwala, HPMC imagwiritsidwa ntchito nthawi zambiri ngati mankhwala omasulidwa, ndipo malamulo ake a viscosity amagwiritsidwa ntchito kuti athetse kutulutsidwa kwa mankhwala; mu zomangamanga, HPMC ntchito monga thickener kusintha workability ndi fluidity wa matope ndi zomatira; mu makampani chakudya, HPMC angagwiritsidwe ntchito monga thickener, emulsifier ndi stabilizer kusintha kukoma ndi maonekedwe a chakudya.

Makhalidwe a mamasukidwe akayendedwe a AnxinCel®HPMC amadzimadzi amadzimadzi ndiye chinsinsi chakugwiritsa ntchito kwake m'magawo osiyanasiyana. Kumvetsetsa ubale wake ndi zinthu monga kukhazikika, kutentha, pH, kulemera kwa mamolekyulu ndi kumeta ubweya ndizofunika kwambiri pakuwongolera magwiridwe antchito komanso kuwongolera magwiridwe antchito.