Hydroxypropyl methylcellulose (HPMC)filimuyo imakhala ndi ntchito zabwino kwambiri, koma chifukwa HPMC ndi gel osakaniza, kukhuthala kwa kutentha kwapansi kumakhala kochepa kwambiri, komwe sikungathandize kuti kupaka (kapena kuviika) ndi kuyanika pa kutentha kochepa kuti akonze filimu yodyera, zomwe zimapangitsa kuti pakhale kusagwira bwino ntchito; kuonjezerapo, mtengo wake wokwera umachepetsa ntchito yake. Hydroxypropyl wowuma (HPS) ndi otsika mtengo gel osakaniza ozizira, Kuwonjezera ake akhoza kuonjezera mamasukidwe akayendedwe a HPMC pa kutentha otsika, kusintha processing ntchito ya HPMC, ndi kuchepetsa mtengo kupanga, kupitirira, yemweyo hydrophilicity , mayunitsi shuga ndi hydroxypropyl magulu onse amathandiza kuti kugwirizana kwa ma polima awiriwa. Chifukwa chake, makina osakanikirana a gel otenthetsera adakonzedwa ndikuphatikiza HPS ndi HPMC, ndipo momwe kutentha kumapangidwira pamapangidwe a gel osakaniza a HPMC / HPS oziziritsa kuzizira kumaphunziridwa mwadongosolo pogwiritsa ntchito rheometer ndi njira yaying'ono yobalalika ya X-ray. , pamodzi ndi chikoka cha kutentha mankhwala zinthu pa microstructure ndi katundu wa dongosolo nembanemba, ndiyeno anamanga ubale gel osakaniza kapangidwe ka dongosolo-matako kamangidwe-machubu katundu pansi pa zinthu kutentha mankhwala.
Zotsatira zimasonyeza kuti kutentha kwambiri, gel osakaniza ndi apamwambaMtengo wa HPMCzomwe zili ndi ma modulus apamwamba komanso machitidwe olimba ngati olimba, mawonekedwe ofananirako a omwaza ma gel ndi ochulukirapo, ndipo kukula kwa magulu a gel ndikokulirapo; pa kutentha kochepa, zomwe zili ndi HPS Zitsanzo za gel okwera zimakhala ndi modulus wapamwamba, khalidwe lodziwika bwino ngati lolimba, komanso mawonekedwe odziimira okha ngati omwaza ma gel. Kwa zitsanzo zokhala ndi chiŵerengero chosakanikirana chofanana, kufunikira kwa modulus ndi khalidwe lolimba-ngati khalidwe ndi kachulukidwe kameneka kamene kamakhala ndi ma gels olamulidwa ndi HPMC pa kutentha kwakukulu ndi apamwamba kuposa omwe amalamulidwa ndi HPS pa kutentha kochepa. The kuyanika kutentha zingakhudze dongosolo gel osakaniza dongosolo pamaso kuyanika, ndiyeno bwanji crystalline dongosolo ndi amorphous dongosolo la filimuyo, ndipo potsiriza zimakhudza kwambiri mawotchi zimatha filimu, chifukwa mumakokedwe mphamvu ndi modulus filimu zouma pa kutentha kwambiri. Kuposa youma pa kutentha otsika. Kuzizira kulibe zotsatira zoonekeratu pamapangidwe a crystalline a dongosolo, koma zimakhudza kachulukidwe ka microdomain yofanana ndi thupi la filimuyo. Mu dongosolo lino, kachulukidwe ka mawonekedwe a filimuyo amatha kukhudza makina a filimuyo. Kuchita kumakhudza kwambiri.
Kutengera kukonzekera kwa nembanemba yosakanikirana, kafukufukuyu adapeza kuti kugwiritsa ntchito njira ya ayodini posankha utoto wosakanikirana wa HPMC/HPS kunakhazikitsa njira yatsopano yowonera momveka bwino kugawa kwagawo ndi kusintha kwa gawo la dongosolo losakanikirana pansi pa maikulosikopu. njira, amene ali methodological kalozera kufunika kwa phunziro la gawo kugawa kachitidwe wowuma ofotokoza mophatikiza. Pogwiritsa ntchito njira yatsopano yofufuzirayi, kuphatikizapo infrared spectroscopy, scanning electron microscopy ndi extensometer, kusintha kwa gawo, kugwirizanitsa ndi makina a makina a dongosololi adawunikidwa ndikuphunziridwa, ndipo kugwirizanitsa, kusintha kwa gawo ndi maonekedwe a filimu kunamangidwa. mgwirizano pakati pa ntchito. Zotsatira zowonera ma microscope zikuwonetsa kuti dongosololi limadutsa kusintha kwa gawo pamene chiŵerengero cha HPS ndi 50%, ndipo chodabwitsa chosakanikirana cha interphase chilipo mufilimuyi, kusonyeza kuti dongosololi liri ndi gawo linalake logwirizana; kusanthula kwa infrared, thermogravimetric ndi zotsatira za SEM zimatsimikiziranso kusakanikirana. Dongosololi lili ndi mulingo wina wogwirizana. Modulus ya filimu yosakanikirana imasintha pamene HPS ili ndi 50%. Pamene aHPSzomwe zili ndi zazikulu kuposa 50%, njira yolumikizirana yachitsanzo chosakanikirana imachoka pamzere wowongoka womwe umalumikiza ngodya zolumikizana ndi zitsanzo zoyera, ndipo ikakhala yochepera 50%, imapatuka molakwika pamzere wowongoka. , zomwe zimayambitsidwa makamaka ndi kusintha kwa gawo.
Nthawi yotumiza: Apr-25-2024