1. Basic katundu wa HPMC
Hydroxypropyl methylcellulose (HPMC)ndi nonionic cellulose ether yomwe imagwiritsidwa ntchito kwambiri pomanga, mankhwala, chakudya, zodzoladzola ndi mafakitale ena. Makhalidwe ake apadera a physicochemical, monga kusungunuka, kukhuthala, kupanga mafilimu ndi kutentha kwa gelation, kumapangitsa kuti ikhale yofunika kwambiri m'mafakitale ambiri. Kutentha ndi chimodzi mwazinthu zazikulu zomwe zimakhudza magwiridwe antchito a HPMC, makamaka pankhani ya kusungunuka, mamasukidwe akayendedwe, matenthedwe amafuta ndi kukhazikika kwamafuta.
2. Mmene kutentha pa solubility wa HPMC
HPMC ndi polima thermoreversibly sungunuka, ndi solubility ake kusintha ndi kutentha:
Kutentha kochepa (madzi ozizira): HPMC imasungunuka mosavuta m'madzi ozizira, koma imayamwa madzi ndikutupa ikalumikizana ndi madzi kuti ipange tinthu tating'onoting'ono ta gel. Ngati kugwedeza sikukwanira, zotupa zimatha kupanga. Choncho, nthawi zambiri tikulimbikitsidwa kuwonjezera HPMC pang'onopang'ono pamene akuyambitsa kulimbikitsa yunifolomu kubalalitsidwa.
Kutentha kwapakatikati (20-40 ℃): Pakutentha uku, HPMC ili ndi kusungunuka kwabwino komanso kukhuthala kwakukulu, ndipo ndiyoyenera machitidwe osiyanasiyana omwe amafunikira kukhuthala kapena kukhazikika.
Kutentha kwakukulu (kupitirira 60 ° C): HPMC imakonda kupanga gel yotentha pa kutentha kwakukulu. Kutentha kukafika pa kutentha kwa gel osakaniza, yankho limakhala losawoneka bwino kapena ngakhale coagulate, zomwe zimakhudza momwe ntchitoyo ikuyendera. Mwachitsanzo, mu zipangizo zomangira monga matope kapena putty powder, ngati kutentha kwa madzi kuli kwakukulu kwambiri, HPMC sichikhoza kusungunuka bwino, motero zimakhudza khalidwe la zomangamanga.
3. Mmene kutentha pa HPMC mamasukidwe akayendedwe
Kukhuthala kwa HPMC kumakhudzidwa kwambiri ndi kutentha:
Kuwonjezeka kwa kutentha, kuchepa kwa mamasukidwe akayendedwe: The mamasukidwe akayendedwe a HPMC yankho nthawi zambiri amachepetsa ndi kuwonjezeka kutentha. Mwachitsanzo, kukhuthala kwa njira ina ya HPMC kungakhale pamwamba pa 20 ° C, pamene pa 50 ° C, kukhuthala kwake kudzatsika kwambiri.
Kutentha kumachepa, mamasukidwe akayendedwe amachira: Ngati yankho la HPMC litakhazikika pambuyo pa kutentha, kukhuthala kwake kumachira pang'ono, koma sikungathe kubwereranso ku chikhalidwe choyambirira.
HPMC ya magiredi amakulidwe osiyanasiyana amakhalidwe osiyana: mkulu-kukhuthala HPMC ndi tcheru kusintha kutentha, pamene otsika mamasukidwe akayendedwe HPMC ali ndi kusinthasintha zochepa mamasukidwe akayendedwe kutentha kusintha. Choncho, m'pofunika kwambiri kusankha HPMC ndi mamasukidwe akayendedwe koyenera mu zochitika zosiyanasiyana ntchito.
4. Mmene kutentha pa matenthedwe gelation a HPMC
Chinthu chofunika kwambiri cha HPMC ndi kutentha kwa kutentha, ndiko kuti, pamene kutentha kumakwera kufika pamlingo wina, yankho lake lidzasanduka gel osakaniza. Kutentha kumeneku kumatchedwa kutentha kwa gelation. Mitundu yosiyanasiyana ya HPMC imakhala ndi kutentha kosiyana kwa gelation, nthawi zambiri pakati pa 50-80 ℃.
M'mafakitale azakudya ndi mankhwala, mawonekedwe a HPMC amagwiritsidwa ntchito pokonzekera mankhwala otulutsidwa kapena ma colloids a chakudya.
Pomanga ntchito, monga matope a simenti ndi ufa wa putty, kutentha kwa kutentha kwa HPMC kungapereke madzi osungiramo madzi, koma ngati kutentha kwa chilengedwe kumakhala kwakukulu, gelation ingakhudze ntchito yomanga.
5. Mmene kutentha pa kukhazikika kwa kutentha kwa HPMC
Mapangidwe a mankhwala a HPMC ndi okhazikika mkati mwa kutentha koyenera, koma kukhudzana ndi kutentha kwa nthawi yaitali kungayambitse kuwonongeka.
Kutentha kwakanthawi kochepa (monga kutentha pompopompo kufika pamwamba pa 100 ℃): sikungakhudze kwambiri mankhwala a HPMC, koma kungayambitse kusintha kwa thupi, monga kuchepa kwa viscosity.
Kutentha kwanthawi yayitali (monga kutentha kosalekeza pamwamba pa 90 ℃): kungayambitse unyolo wa mamolekyu a HPMC kusweka, zomwe zimapangitsa kuchepa kosasinthika kwa viscosity, zomwe zimakhudza kukhuthala kwake komanso kupanga mafilimu.
Kutentha kwambiri (kupitirira 200 ℃): HPMC ikhoza kuwola chifukwa cha kutentha, kutulutsa zinthu zosasunthika monga methanol ndi propanol, ndikupangitsa kuti zinthuzo ziwonongeke kapena ngakhale carbonize.
6. Malangizo ogwiritsira ntchito HPMC m'malo osiyanasiyana otentha
Kuti mupereke sewero lathunthu pakuchita kwa HPMC, njira zoyenera ziyenera kuchitidwa molingana ndi kutentha kosiyanasiyana:
M'malo otentha otsika (0-10 ℃): HPMC imasungunuka pang'onopang'ono, ndipo tikulimbikitsidwa kuti isungunuke m'madzi ofunda (20-40 ℃) musanagwiritse ntchito.
M'malo otentha (10-40 ℃): HPMC imakhala yokhazikika ndipo ndiyoyenera kugwiritsa ntchito zambiri, monga zokutira, matope, zakudya ndi zopangira mankhwala.
Pamalo otentha kwambiri (pamwamba pa 40 ℃): Pewani kuwonjezera HPMC mwachindunji pamadzi otentha kwambiri. Ndibwino kuti musungunuke m'madzi ozizira musanatenthe, kapena musankhe HPMC yosamva kutentha kwambiri kuti muchepetse mphamvu ya gelation pakugwiritsa ntchito.
Kutentha kumakhudza kwambiri kusungunuka, mamasukidwe akayendedwe, matenthedwe a gelation ndi kukhazikika kwamafuta.Mtengo wa HPMC. Panthawi yogwiritsira ntchito, m'pofunika kusankha moyenerera chitsanzo ndi njira yogwiritsira ntchito HPMC molingana ndi kutentha kwapadera kuti zitsimikizire kuti zimagwira ntchito bwino. Kumvetsetsa kutentha kwa kutentha kwa HPMC sikungangowonjezera ubwino wa mankhwala, komanso kupewa kutaya kosafunikira chifukwa cha kusintha kwa kutentha ndikuwongolera kupanga bwino komanso phindu lachuma.
Nthawi yotumiza: Mar-28-2025