Gịnị bụ serial nọmba nke Hydroxypropyl Methylcellulose?

Hydroxypropyl Methylcellulose (HPMC)bụ ụdị cellulose a na-agbanwe nke ọma nke a na-ejikarị eme ihe n'ọtụtụ ụlọ ọrụ dịka ọgwụ, mmepụta nri, na ihe owuwu. Ọ bụ ngwakọta dị iche iche, nke a na-ejikarị eme ihe dị ka ihe na-esi ísì, ihe nkedo, onye na-emepụta ihe nkiri, na stabilizer. Agbanyeghị, ọ nweghị “nọmba serial” akọwapụtara n'echiche ọdịnala, dị ka ngwaahịa ma ọ bụ nọmba akụkụ ị nwere ike ịhụ na mpaghara nrụpụta ndị ọzọ. Kama, a na-amata HPMC site na nhazi kemịkal ya na ọtụtụ njirimara, dị ka ogo nnọchi na viscosity.

Ozi izugbe gbasara Hydroxypropyl Methylcellulose (HPMC)

Nhazi kemịkalụ: A na-eme HPMC site n'ịgbanwe cellulose nke ọma site na nnọchi nke otu hydroxyl (-OH) na otu hydroxypropyl na methyl. Ndochi a na-agbanwe ihe ndị dị na cellulose, na-eme ka ọ na-agbaze na mmiri ma na-enye ya ihe pụrụ iche dị ka ike ịmepụta ihe nkiri, ike njide, na ike ijido mmiri.

Ndị na-achọpụtakarị na ịkpọ aha

Nchọpụta nke Hydroxypropyl Methylcellulose na-adaberekarị n'ụdị nkwekọrịta aha dị iche iche nke na-akọwa nhazi na akụrụngwa ya:

Nọmba CAS:

Ọrụ Abstracts Chemical (CAS) na-ekenye ihe nchọpụta pụrụ iche na ihe ọ bụla kemịkal. Nọmba CAS maka Hydroxypropyl Methylcellulose bụ 9004-65-3. Nke a bụ ọnụọgụ ahaziri nke ndị kemist, ndị na-ebubata ngwaahịa na ndị na-ahụ maka nhazi na-eji na-ezo aka na ihe ahụ.

Koodu InChi na SMILES:

InChi (International Chemical Identifier) ​​bụ ụzọ ọzọ na-anọchi anya nhazi kemịkal nke ihe. HPMC ga-enwe eriri InChi ogologo nke na-anọchi anya usoro ihe omimi ya n'ụdị ahaziri ahazi.

SMILES (Simplified Molecular Input Line Entry System) bụ usoro ọzọ ejiri na-anọchi anya ụmụ irighiri ihe n'ụdị ederede. HPMC nwekwara koodu SMILES kwekọrọ, ọ bụ ezie na ọ ga-adị mgbagwoju anya n'ihi nnukwu ọdịdị nke nhazi ya.

Nkọwapụta ngwaahịa:

N'ahịa azụmaahịa, a na-amatakarị HPMC site na nọmba ngwaahịa, nke nwere ike ịdị iche site na ndị nrụpụta. Dịka ọmụmaatụ, onye na-ebubata nwere ike ịnwe ọkwa dịka HPMC K4M ma ọ bụ HPMC E15. Ihe nchọpụta ndị a na-ezokarị aka na viscosity nke polymer na ngwọta, nke a na-ekpebi site na ogo methylation na hydroxypropylation yana ịdị arọ molecular.

Ụdị akara ule Hydroxypropyl Methylcellulose (HPMC)

Njirimara nke Hydroxypropyl Methylcellulose dịgasị iche dabere na ogo nnọchi nke otu methyl na hydroxypropyl, yana ịdị arọ molekụla. Ọdịiche ndị a na-ekpebi viscosity na solubility HPMC na mmiri, nke na-emetụta ngwa ya na ụlọ ọrụ dị iche iche.

N'okpuru bụ tebụl na-akọwapụta ọkwa dị iche iche nke Hydroxypropyl Methylcellulose:

Ngwakọta zuru oke yana akụrụngwa nke HPMC

Njirimara anụ ahụ nke Hydroxypropyl Methylcellulose dabere na oke nnọchi nke otu hydroxyl n'ime molekul cellulose. Nke a bụ akụrụngwa ndị bụ isi:

Ogo nke nnọchi (DS):

Nke a na-ezo aka na ole n'ime otu hydroxyl dị na cellulose ejirila methyl ma ọ bụ hydroxypropyl dochie anya. Ogo nke nnọchi na-emetụta solubility nke HPMC n'ime mmiri, viscosity ya, yana ike imepụta ihe nkiri. Ụdị DS maka HPMC sitere na 1.4 ruo 2.2, dabere na ọkwa.

Viscosity:

A na-ahazi akara ule HPMC dabere na viscosity ha mgbe agbazere na mmiri. Ihe dị elu nke ịdị arọ molekụla na ogo nke nnọchi, ka viscosity dị elu. Dịka ọmụmaatụ, a na-ejikarị HPMC K100M (nke nwere oke viscosity dị elu) na-ejikarị eme ihe na nhazi ọgwụ na-achịkwa, ebe akara viscosity dị ala dị ka HPMC K4M na-ejikarị eme ihe maka mbadamba mbadamba na ngwa nri.

Solubility mmiri:

HPMC bụ soluble na mmiri ma na-etolite ihe dị ka gel mgbe agbazere, ma okpomọkụ na pH nwere ike imetụta ya solubility. Dịka ọmụmaatụ, n'ime mmiri oyi, ọ na-agbaze ngwa ngwa, mana ike ya nwere ike ibelata na mmiri ọkụ, karịsịa n'ọtụtụ dị elu.

Ikike imepụta ihe nkiri:

Otu n'ime isi ihe dị na Hydroxypropyl Methylcellulose bụ ikike ya ịmepụta ihe nkiri na-agbanwe agbanwe. Ngwongwo a na-eme ka ọ dị mma iji mee ihe na mkpuchi mbadamba, ebe ọ na-enye ebe dị mma, na-achịkwa ntọhapụ. Ọ na-abakwa uru na ụlọ ọrụ nri iji meziwanye ederede na ndụ nchekwa.

Gelation:

N'ebe ụfọdụ na ọnọdụ okpomọkụ, HPMC nwere ike ịmepụta gels. Ngwongwo a bara uru na usoro ọgwụ, ebe a na-eji ya mepụta usoro ntọhapụ na-achịkwa.

Ngwa nke Hydroxypropyl Methylcellulose

Ụlọ ọrụ ọgwụ:

A na-eji HPMC dị ka ihe nkedo n'ụdị mbadamba, ọkachasị na sistemụ ntọhapụ agbatịgoro yana njikwa njikwa. Ọ na-ejekwa ozi dị ka ihe mkpuchi maka mbadamba nkume na capsules iji chịkwaa ntọhapụ nke ihe na-arụ ọrụ. Ikike ya ịmepụta ihe nkiri kwụsiri ike na gels dị mma maka usoro nnyefe ọgwụ.

Ụlọ ọrụ nri

N'ụlọ ọrụ nri, a na-eji HPMC eme ihe dị ka ihe na-eme ka ọ sie ike, emulsifier, na stabilizer n'ụdị ngwaahịa dị iche iche, gụnyere sauces, akwa akwa, na ngwaahịa sie. Ọ na-enyere aka melite udidi na ịgbatị ndụ nchekwa site na ibelata mmiri mmiri.

Ihe ịchọ mma na nlekọta onwe onye:

A na-eji HPMC eme ihe n'ọtụtụ ebe na ihe ịchọ mma, ebe ọ na-arụ ọrụ dị ka ihe na-eme ka ihe na-eme ka ahụ sie ike na ude, lotions, shampoos, na ngwaahịa nlekọta onwe onye ndị ọzọ. Ikike ya ịmepụta usoro gel bara uru karịsịa na ngwa ndị a.

Ụlọ ọrụ ihe owuwu:

N'ebe a na-ewu ihe owuwu, karịsịa na ciment na plasta, a na-eji HPMC eme ihe dị ka ihe na-ejigide mmiri. Ọ na-enyere aka melite workability na enhances bonding Njirimara nke ihe.

Ngwa ndị ọzọ:

A na-ejikwa HPMC n'ọrụ na ụlọ ọrụ akwa akwa, mkpuchi akwụkwọ, na ọbụna n'imepụta ihe nkiri na-emebi emebi.

Hydroxypropyl Methylcellulose (HPMC)bụ ihe na-agbanwe agbanwe nke ukwuu ejiri n'ofe ụlọ ọrụ dị iche iche n'ihi ihe ndị pụrụ iche ya dị ka ike ịmepụta ihe nkiri, ike ịgbatị, na njide mmiri. Ọ bụ ezie na ọ nweghị “nọmba serial” n'echiche nkịtị, a na-amata ya site na njirimara kemịkalụ dị ka nọmba CAS ya (9004-65-3) yana akara ngwaahịa akọwapụtara (dịka ọmụmaatụ, HPMC K100M, HPMC E4M). Ọdịiche dị iche iche nke akara ule HPMC dị na-eme ka ọ dị mkpa na mpaghara dị iche iche, site na ọgwụ na nri, ihe ịchọ mma, na ihe owuwu.