He aha nā waiwai kino o ka hydroxypropyl methylcellulose?

1. ʻO ke ʻano a me ka solubility

ʻO ka HPMC he pauka keʻokeʻo keʻokeʻo a keʻokeʻo paha, ʻaʻala ʻole, ʻono ʻole a ʻona ʻole. Hiki ke hoʻoheheʻe ʻia i loko o ka wai anuanu a me kekahi mau mea hoʻoheheʻe kūlohelohe (e like me nā mea hoʻoheheʻe hui ʻia e like me ka ethanol/wai a me ka acetone/wai), akā ʻaʻole hiki ke hoʻoheheʻe ʻia i loko o ka ethanol maʻemaʻe, ka etera a me ka chloroform. Ma muli o kona ʻano non-ionic, ʻaʻole ia e hoʻokō i ka hopena electrolytic i ka wai wai a ʻaʻole e hoʻopilikia nui ʻia e ka waiwai pH.

2. Viscosity a me ka rheology

ʻO ka hoʻonā wai HPMC he mānoanoa maikaʻi a me ka thixotropy. ʻO nā ʻano like ʻole o AnxinCel®HPMC he mau viscosities like ʻole, a ʻo ka laulā maʻamau ʻo 5 a 100000 mPa·s (2% aqueous solution, 20°C). Hōʻike kona hopena i ka pseudoplasticity, ʻo ia hoʻi, shear thinning phenomenon, a kūpono i nā hiʻohiʻona noiʻi e like me nā uhi, slurries, adhesives, a me nā mea e pono ai ka rheology maikaʻi.

3. ʻO ka wai wela

Ke hoʻomehana ʻia ka HPMC i ka wai, e emi ana ke aniani o ka hoʻonā a hoʻokumu ʻia ka gel i kahi mahana. Ma hope o ka hoʻoluʻu ʻana, e hoʻi ka mokuʻāina gel i ke kūlana hoʻonā. Loaʻa nā ʻano wela gel like ʻole o nā ʻano like ʻole o ka HPMC, ma waena o 50 a 75°C. He mea koʻikoʻi kēia waiwai i nā noi e like me ke kūkulu ʻana i ka mortar a me nā capsules pharmaceutical.

4. Hana ʻili

No ka mea, loaʻa nā pūʻulu hydrophilic a me nā pūʻulu hydrophobic HPMC, hōʻike lākou i kekahi hana ma luna a hiki ke pāʻani i kahi hana emulsifying, dispersing a me ka hoʻokūpaʻa. No ka laʻana, i nā uhi a me nā emulsions, hiki i ka HPMC ke hoʻomaikaʻi i ka paʻa o ka emulsion a pale i ka sedimentation o nā ʻāpana puaʻa.

5. Hygroscopicity

Loaʻa i ka HPMC kahi hygroscopicity a hiki ke hoʻopaʻa i ka makū ma kahi ʻano haʻahaʻa. No laila, i kekahi mau noi, pono e uku ʻia ka nānā ʻana i ka hoʻopaʻa ʻana i ka hoʻopaʻa ʻana i mea e pale ai i ka komo ʻana o ka wai a me ka agglomeration.

6. Waiwai hana kiʻiʻoniʻoni

Hiki i ka HPMC ke hana i kahi kiʻiʻoniʻoni paʻakikī a maopopo, i hoʻohana nui ʻia i ka meaʻai, lāʻau lapaʻau (e like me nā mea hoʻopili) a me nā uhi. No ka laʻana, ma ka ʻoihana lāʻau lapaʻau, hiki ke hoʻohana ʻia ke kiʻi ʻoniʻoni HPMC e like me ka uhi papa e hoʻomaikaʻi i ka paʻa o ka lāʻau a me ka hoʻokuʻu ʻana.

7. Biocompatibility a me ka palekana

ʻO ka HPMC he meaʻawaʻawaʻole a me ka pōʻinoʻole, a hiki ke hoʻololi maikaʻiʻia e ke kino kanaka, no laila ua hoʻohana nuiʻia i ka lāʻau lapaʻau a me ka meaʻai. Ma ke ʻano he lāʻau lapaʻau, hoʻohana maʻamau ia e hana i nā papa hoʻokuʻu hoʻokuʻu ʻia, nā pūpū capsule, etc.

8. pH kūpaʻa o ka hopena

Paʻa ka HPMC i ka pae pH o 3 a hiki i ka 11, a ʻaʻole hiki ke hoʻohaʻahaʻa ʻia a hoʻoheheʻe ʻia e ka waikawa a me ka alkali, no laila hiki ke hoʻohana ʻia i nā ʻōnaehana kemika like ʻole, e like me nā mea kūkulu hale, nā huahana kemika o kēlā me kēia lā a me nā hoʻomākaukau lāʻau.