Sidee bay urta hydroxypropyl methylcellulose u saamaysaa tayada?

Waa maxay saamaynta cabbirka urta ee hydroxypropyl methylcellulose:

Synthesis ofhydroxypropyl methylcellulose: Ku daawee cellulose suuf ah oo la safeeyey oo leh lye at 35-40 ° C nus saac, riix, burburi cellulose, iyo da'da si sax ah 35 ° C, si celcelis ahaan heerka polymerization ee alkali helay waa gudaha gudaha fiilooyinka kala duwan ee loo baahan yahay. Ku rid faybarka alkali ee kiliyaha etherification, ku dar propylene oxide iyo methyl chloride si isku xigta, oo ku ether ka 50-80 ° C ilaa 5 saacadood, cadaadiska ugu badan wuxuu ku saabsan yahay 1.8MPa. Ka dib ku dar qadar ku habboon oo ah hydrochloric acid iyo oxalic acid biyaha kulul ee 90 ° C si aad u dhaqdo walxaha si loo ballaariyo mugga. Fuuqbaxa ku jira centrifuge. Ku dhaq biyo ilaa dhexdhexaad. Marka qoyaanka maaddadu ay ka hooseyso 60%, ku qalaji qulqulka hawo kulul 130 ° C ilaa qoyaanku ka hooseeyo 5%.

HPMC-da ay soo saarto habka dareeraha waxay u isticmaashaa toluene iyo isopropanol sida dareereyaal. Haddii maydhistu aanay wanaagsanayn, ur yar ayaa baaqi doonta. Waqtigan xaadirka ah, tayada HPMC ee hydroxypropyl methylcellulose aad ayey u kala duwan tahay, qiimuhuna aad buu u kala duwan yahay, taasoo adkeyneysa macaamiisha inay sameeyaan doorasho sax ah. Tani waa dhibaatada habka dhaqidda, ma saameynayso isticmaalka mana jirto wax dhib ah, HPMC saafi ah waa inaysan urin ammonia, istaarij iyo aalkolo; sinaystayHPMCinta badan waxay urin karaan dhammaan noocyada urta, xitaa haddii aysan dhadhan lahayn, waxay dareemi doontaa culeys. Si kastaba ha ahaatee, hydroxypropyl methylcellulose ee ay soo saaraan warshado badan ayaa leh ur gaar ah oo xooggan iyo ur daran. Tayada hubaal maaha ilaa heer.

Hypromellose waxaa lagu helaa suuf la safeeyey oo leh dareere naadir ah si loo helo cellulose alkaline, ka dibna lagu daro dareeraha, wakiilka etherification, toluene, iyo isopropanol ee falcelinta etherification, nadiifinta dhaqidda, qalajinta, burburinta, iwm. Waa hagaag, waxaa jiri doona ur, si dadka isticmaala ay u isticmaali karaan si kalsooni leh.