Hydroxypropyl Methylcellulose (HPMC) iyoHydroxyethyl Cellulose (HEC) waa labadaba cellulose derivatives, oo si weyn loogu isticmaalo warshadaha, daawada, qurxinta iyo beeraha kale. Kala duwanaanshahooda ugu weyn waxay ka muuqdaan qaab-dhismeedka molecular, sifooyinka xalalka, goobaha codsiga iyo dhinacyo kale.
1. Qaab-dhismeedka molecular
Hydroxypropyl Methylcellulose (HPMC)
HPMC waa derivative biyo-milmi leh oo lagu soo bandhigay methyl (-CH3) iyo hydroxypropyl (-CH2CHOHCH3) kooxaha silsiladda unugyada cellulose. Gaar ahaan, qaab-dhismeedka molecular ee HPMC waxa uu ka kooban yahay laba beddel oo shaqaynaya, methyl (-OCH3) iyo hydroxypropyl (-OCH2CH(OH)CH3). Caadi ahaan, saamiga hordhaca ah ee methyl ayaa sarreeya, halka hydroxypropyl ay si wax ku ool ah u wanaajin karto milanka cellulose.
Hydroxyethyl Cellulose (HEC)
HEC waa soosaar ay soo bandhigtay kooxaha ethyl (-CH2CH2OH) ee silsiladda molecular cellulose. Qaab dhismeedka cellulose hydroxyethyl, hal ama in ka badan kooxaha hydroxyl (-OH) ee cellulose waxaa lagu bedelay kooxaha ethyl hydroxyl (-CH2CH2OH). Si ka duwan HPMC, qaab-dhismeedka molecular ee HEC waxa uu leeyahay hal kaliya oo lagu beddelo hydroxyethyl oo kuma jiraan kooxaha methyl.
2. Biyo milanka
Kala duwanaanshaha qaabdhismeedka awgeed, milanka biyaha ee HPMC iyo HEC way ka duwan yihiin.
HPMC: HPMC waxay leedahay milmi biyo wanaagsan, gaar ahaan dhexdhexaad ama waxoogaa alkaline ah qiyamka pH, milmayntiisu way ka fiican tahay HEC. Soo bandhigida kooxaha methyl iyo hydroxypropyl waxay wanaajisaa milmaheeda waxayna sidoo kale kordhin kartaa viscosity iyada oo la falgasha unugyada biyaha.
HEC: HEC inta badan waxay ku milmi kartaa biyaha, laakiin milmahoodu aad bay u liidataa, gaar ahaan biyaha qabow, waxayna badanaa u baahan tahay in lagu milmo xaaladaha kuleylka ama waxay u baahan tahay uruurin sare si loo gaaro saameyn la mid ah viscosity. Solubility waxay la xiriirtaa kala duwanaanshaha qaabdhismeedka cellulose iyo hydrophilicity ee kooxda hydroxyethyl.
3. Viscosity iyo sifooyinka rheological
HPMC: Sababtoo ah joogitaanka laba kooxood oo hydrophilic oo kala duwan (methyl iyo hydroxypropyl) ee molecules-keeda, HPMC waxay leedahay sifooyin hagaajinta viscosity wanaagsan ee biyaha waxaana si ballaaran loo isticmaalaa koollada, dahaarka, saabuunta, diyaarinta daawooyinka iyo beeraha kale. Heerarka kala duwan, HPMC waxa ay ku siin kartaa wax ka beddelka mawjadaha hoose ilaa mawjadaha sare, iyo viscosity-ku aad ayuu ugu nugul yahay isbeddellada pH.
HEC: Viscosity-ka HEC waxa kale oo lagu hagaajin karaa iyadoo la beddelo diiradda, laakiin cabbirkeeda hagaajinta viscosity waa ka cidhiidhsan yahay kan HPMC. HEC waxaa inta badan loo isticmaalaa xaaladaha loo baahan yahay viscosity hoose ama dhexdhexaad, gaar ahaan dhismaha, saabuunta iyo alaabta daryeelka shakhsi ahaaneed. Sifooyinka rheological ee HEC waa kuwo deggan, gaar ahaan meelaha aashitada ama dhexdhexaadka ah, HEC waxay ku siin kartaa viscosity xasilloon.
4. Goobaha codsiga
Hydroxypropyl methylcellulose (HPMC)
Warshadaha dhismaha: HPMC waxaa caadi ahaan loo adeegsadaa hoobiye sibidhka iyo dahaarka warshadaha dhismaha si loo hagaajiyo dareeraha, shaqaynta iyo ka hortagga dildilaaca.
Warshadaha dawooyinka: Sida wakiilka xakamaynta daroogada, HPMC waxaa si weyn loogu isticmaalaa warshadaha dawooyinka. Looma isticmaali karo oo kaliya sidii wakiilka samaynta ee kiniiniyada iyo kaabsalka, laakiin sidoo kale sida koollo si ay u caawiso in daawada si siman loo sii daayo.
Warshadaha cuntada: HPMC waxaa inta badan loo isticmaalaa habaynta cuntada sida xasiliye, dhumuc ama emulsifier si loo horumariyo dhadhanka cuntada.
Warshadaha qurxinta: dhumuc ahaan ahaan, HPMC waxaa si weyn loogu isticmaalaa alaabada sida kiriimyada, shaambooyinka, iyo qaboojiyaha si loo kordhiyo viscosity iyo xasiloonida alaabta.
Hydroxyethyl cellulose (HEC)
Warshadaha dhismaha: HEC waxaa badanaa loo isticmaalaa sibidhka, gypsum, iyo xabagta tile si loo hagaajiyo dareeraha iyo wakhtiga haynta alaabta.
Nadiifiyeyaasha: HEC waxaa badanaa loo isticmaalaa nadiifiyeyaasha guriga, saabuunta dharka lagu dhaqo iyo alaabada kale si loo kordhiyo viscosity ee alaabta oo loo hagaajiyo saamaynta nadiifinta.
Warshadaha la isku qurxiyo: HEC waxaa si weyn loogu isticmaalaa alaabada daryeelka maqaarka, shaambada qubeyska, shaambooyinka, iwm. sidii dhumuc iyo hakin si loo hagaajiyo qaabdhismeedka iyo xasiloonida alaabta.
Soo saarista saliidda: HEC waxa kale oo loo isticmaali karaa habka soo saarista saliidda sidii dhumuc ee dareeraha qodista biyaha ku salaysan si ay u caawiso kordhinta viscosity ee dareeraha iyo hagaajinta saamaynta qodista.
5. xasilloonida pH
HPMC: HPMC aad bay ugu nugul yihiin isbeddellada pH. Marka la eego xaaladaha acidic, milanka HPMC ayaa hoos u dhacaya, taas oo saameyn karta waxqabadkeeda. Sidaa darteed, waxaa badanaa loo isticmaalaa meel dhexdhexaad ah ama wax yar oo alkaliin ah.
HEC: HEC ayaa weli ah mid deggan marka loo eego cabbirka pH ballaaran. Waxay leedahay laqabsi xoog leh oo ku wajahan deegaanka acidic iyo alkaline, sidaas darteed waxaa badanaa loo isticmaalaa qaabab u baahan xasillooni xooggan.
HPMCiyoHECku kala duwan yihiin qaab-dhismeedka molecular, solubility, waxqabadka hagaajinta viscosity, iyo meelaha codsiga. HPMC waxay leedahay milanka biyaha wanaagsan iyo waxqabadka hagaajinta viscosity, waxayna ku habboon tahay codsiyada u baahan muuqasho sare ama waxqabad gaar ah oo siideynta ah; halka HEC ay leedahay xasillooni pH oo wanaagsan iyo codsiyo badan oo kala duwan, waxayna ku habboon tahay munaasabadaha u baahan dhexdhexaad dhexdhexaad ah iyo mid hooseeya iyo la qabsiga deegaanka oo xooggan. Codsiyada dhabta ah, doorashada alaabta loo baahan yahay in lagu qiimeeyo iyadoo lagu saleynayo baahiyo gaar ah.
Waqtiga boostada: Febraayo-24-2025