1. Croscarmellose sodium(CMCNa feso'ota'i fa'asagatau): o se copolymer feso'ota'i feso'ota'i o CMNCa
Meatotino: Pa'epa'e po'o le pa'epa'e pa'epa'e. Ona o le faʻaogaina o fesoʻotaʻiga, e le mafai ona faʻafefe i le vai; e fufula vave i le vai i le 4-8 taimi lona voluma muamua. O le pauta e lelei le suavai.
Fa'aoga: O le fa'aoga sili ona fa'aaogaina. Disintegrant mo laulau tuugutu, capsules, granules.
2. Carmellose calcium (feso'ota'i fa'asagatau CMCCa):
Meatotino: Paʻepaʻe, paʻu e leai se manogi, hygroscopic. 1% fofo pH 4.5-6. Toeititi lava le mafai ona solu i le ethanol ma le eter solvent, e le mafai ona solu i le vai, e le mafai ona solu i le dilute hydrochloric acid, teisi soluble i le dilute alkali. po'o le pauta pa'epa'e. Ona o le faʻaogaina o fesoʻotaʻiga, e le mafai ona faʻafefe i le vai; e fula pe a mitiia vai.
Fa'aaogāina: fa'ama'i fa'ama'i, fa'amau, fa'amalulu.
3. Methylcellulose (MC):
Fa'atulagaga: methyl ether o le cellulose
Meatotino: Pa'epa'e i le samasama pa'epa'e pa'epa'e po'o granules. E le mafai ona faʻafefe i le vai vevela, vaifofo masima tumu, ava malosi, eter, acetone, toluene, chloroform; solu i le suka acetic acid po'o se fa'afefiloi tutusa o le ava malosi ma le chloroform. O le solubility i le vai malulu e fesoʻotaʻi ma le tikeri o le suia, ma e sili ona solu pe a o le tikeri o le sui e 2.
Fa'aoga: fa'apipi'i laupapa, fa'ama'i fa'ama'i fa'ama'i fa'ama'i po'o sauniuniga fa'asa'oloto, kulimi po'o gel, so'o fa'amautu ma sui mafiafia, fa'apipi'i laupapa, fa'amautu emulsion.
4. Ethyl cellulose (EC):
Fa'atulagaga: Ethyl ether of cellulose
Meatotino: Paʻepaʻe poʻo samasama-paʻepaʻe paʻu ma granules. E le mafai ona solu i le vai, sua o le manava, glycerol ma propylene glycol. E faigofie ona solu i le chloroform ma toluene, ma fai ai se pa'epa'e pa'epa'e i le tulaga o le ethanol.
Talosaga: O se mea e sili ona lelei e feaveaʻi ai le vai, e talafeagai e pei o le vai-maʻaleʻale vailaʻau faʻamaʻi, vai e le mafai ona faʻafefeteina, mea faʻapipiʻi papa, mea ata tifaga, mea microcapsule ma mea faʻapipiʻi faʻamalolo, ma isi.
5. Hydroxyethyl Cellulose (HEC):
Fa'atulagaina: Vaega hydroxyethyl eter ole cellulose.
Meatotino: lanu samasama mama po'o le susu pa'epa'e pa'epa'e. Soluble atoatoa i le vai malulu, vai vevela, vai vaivai, faavae vaivai, malosi malosi, faavae malosi, insoluble i le tele o solvents organic (soluble in dimethyl sulfoxide, dimethylformamide), i diol polar organic solvents E mafai ona faʻalautele pe faʻamaʻapeina se vaega.
Talosaga: mea e le mafai ona solu i le vai-soluble polymer; mafiafia mo sauniuniga o mata, otology ma fa'aoga autu; HEC i lubricants mo mata mago, tioata faʻafesoʻotaʻi ma gutu mago; fa'aaogaina i mea teuteu. I le avea ai o se mea faʻapipiʻi, faʻapipiʻi ata, sui faʻamalosi, sui faʻamalolo ma faʻamautu mo vailaʻau ma meaʻai, e mafai ona faʻapipiʻi vaega o vailaʻau, ina ia mafai ai e vailaʻau vailaʻau ona faʻagasolo lemu.
6. Hydroxypropyl Cellulose (HPC):
Fa'atulagaga: Vaega polyhydroxypropyl eter ole cellulose
Meatotino: HPC maualuga e suitulaga i le pa'epa'e po'o le pa'u samasama laititi. Solu i le methanol, ethanol, propylene glycol, isopropanol, dimethyl sulfoxide ma le dimethyl formamide, o le maualuga viscosity version e itiiti soluble. E le mafai ona solu ile vai vevela, ae mafai ona fula. Gelation vevela: faigofie solu i le vai i lalo o le 38°C, gelatinized e ala i le faamafanafanaina, ma fausia fulafula fulafula i le 40-45°C, lea e mafai ona toe maua mai i le malulu.
L-HPC uiga mataʻina: e le mafai ona faʻafefe i le vai ma soʻo faʻalagona, ae fulafula i le vai, ma faʻateleina meatotino fula ma faʻateleina mea e suitulaga
Talosaga: O le HPC maualuga-sui e faʻaaogaina e fai ma fusi papa, sui granulating, mea faʻapipiʻi ata tifaga, ma e mafai foi ona faʻaaogaina e pei o mea ata tifaga microencapsulated, mea matrix ma mea faʻapipiʻi o le gastric taofi papa, mafiafia ma Colloids Puipuia, e masani ona faʻaaogaina i patches transdermal.
L-HPC: E masani ona faʻaaogaina e avea o se laulau faʻamaʻi poʻo se mea faʻapipiʻi mo le susu susu, e pei o se matrix papamaʻa faʻamalolo, ma isi.
7. Hypromellose (HPMC):
Fauga: Vaega methyl ma vaega polyhydroxypropyl ether o cellulose
Meatotino: Pa'epa'e po'o le pa'epa'e pa'epa'e fa'alava po'o le pa'u pa'epa'e. E solu i le vai malulu, e le mafai ona fa'afefeteina i le vai vevela, ma e iai mea fa'afefeteina. E soluble i le methanol ma vaifofo ethanol, chlorinated hydrocarbons, acetone, ma isi. O lona solubility i solu organic e sili atu nai lo vai soluble.
Talosaga: O lenei oloa o se vaifofo vai maualalo-viscosity fa'aaogaina e fai ma mea e ufiufi ai ata; e fa'aaogaina se vaifofo solvent organic maualuga-viscosity e fai ma fusi papa, ma e mafai ona fa'aoga le oloa maualuga-viscosity e poloka ai le fa'amatu'u o vaila'au fa'asaina vai; e pei o mata'u mata mafiafia mo le lacquer ma loimata faafoliga, ma le susū mea mo tioata faafesootai.
8. Hypromellose Phthalate (HPMCP):
Fa'atulagaga: HPMCP o le phthalic acid afa ester o le HPMC.
Meatotino: Beige poʻo paʻepaʻe paʻepaʻe poʻo granules. E le mafai ona solu i le vai ma le vaifofo oona, e le mafai ona solu ile hexane, ae faigofie ona solu ile acetone:methanol, acetone:ethanol po'o le methanol:chloromethane paluga.
Talosaga: O se ituaiga fou o mea faʻapipiʻi ma faʻatinoga sili ona lelei, lea e mafai ona faʻaaogaina e fai ma faʻapipiʻi ata e ufiufi ai le manogi uiga ese o papa poʻo granules.
9. Hypromellose Acetate Succinate (HPMCAS):
Fa'a: fa'afefiloi acetic ma succinic esters oHPMC
Meatotino: Pa'epa'e i le samasama pa'epa'e pa'epa'e po'o granules. Soluble i le sodium hydroxide ma le sodium carbonate solution, faigofie ona solu i le acetone, methanol poʻo le ethanol: vai, dichloromethane: faʻafefiloi ethanol, e le mafai ona faʻafefe i le vai, ethanol ma eter.
Fa'aoga: E pei o mea fa'apipi'i fa'apipi'i, mea fa'apipi'i fa'amalolo ma mea e ufiufi ata.
10. Akara:
Fausia: Agar o se faʻafefiloi o le itiiti ifo ma le lua polysaccharides, e tusa ma le 60-80% neutral agarose ma le 20-40% agarose. O le Agarose o lo'o tu'ufa'atasia i iunite fa'asolosolo a agarobiose lea e feso'ota'i fa'atasi ai le D-galactopyranosose ma le L-galactopyranosose ile 1-3 ma le 1-4.
Meatotino: Akara e feliuliua'i, pa'u faatafafa samasama mama, ta'avale pupu'e po'o pa'u pa'u po'o mea pauta. E le mafai ona solu i le vai malulu, solu i le vai vai. Fufulu 20 taimi ile vai malulu.
Talosaga: E pei o le fusifusia sui, suauu faavae, faavae suppository, emulsifier, stabilizer, suspending sooupu, faapea foi poultice, capsule, syrup, jelly ma emulsion.
Taimi meli: Apr-26-2024