Hydroxypropyl Methylcellulose (HPMC): Incamake n'ingaruka ku mubiri

Hydroxypropyl methylcellulose (HPMC)ni igice cya sintetike ya polymer ikomoka kuri selile, igice cyingenzi cyimiterere yinkuta za selile. Ifite uburyo butandukanye bwo gukoresha imiti, ibikomoka ku biribwa, kwisiga, ndetse no gukoresha inganda. Mu mubiri, AnxinCel®HPMC igira ingaruka zitandukanye bitewe nuburyo ikoreshwa, kandi mugihe muri rusange ifatwa nkumutekano mukoresha no kuyikoresha, ingaruka zayo zirashobora gutandukana bitewe na dosiye, inshuro zikoreshwa, hamwe nubukangurambaga bwa buri muntu.

Hydroxypropyl Methylcellulose ni iki?

Hydroxypropyl methylcellulose ni selile yahinduwe, aho amwe mumatsinda ya hydroxyl muri molekile ya selile yasimbujwe hydroxypropyl na methyl. Ihinduka ryongera imbaraga zamazi mumazi kandi ryongera ubushobozi bwo gukora geles. HPMC ikoreshwa nka stabilisateur, kubyimbye, guhuza, na emulisiferi mubicuruzwa byinshi.

Imiti yimiti ya HPMC ni C₆₀H₁₀₀O₅₀ · ₓ, kandi igaragara nkifu yera cyangwa yera. Ntabwo ari uburozi, ntibitera uburakari, kandi ntabwo ari allergeque, nubwo ibisubizo byabantu bishobora gutandukana.

Ibyingenzi Byingenzi bya Hydroxypropyl Methylcellulose:

Imiti:

Guhambira no kuzuza:HPMC ikoreshwa muburyo bwa tablet kugirango ihuze ibiyigize hamwe. Ifasha kwemeza uburinganire n'ubwuzuzanye.

Kugenzura-Kurekura Sisitemu:HPMC ikoreshwa muburyo bwagutse-burekura ibinini cyangwa capsules kugirango bigabanye gusohora ibintu bikora mugihe.

Umukozi wo gutwikira:HPMC ikoreshwa kenshi mu gutwikira ibinini na capsules, ikumira imiti ikora nabi, igahindura ituze, kandi ikongerera abarwayi kubahiriza.

Ibinyobwa:Muburyo bumwe bwo kunwa mu kanwa, HPMC irashobora gufasha kwinjiza amazi no kongera igice kinini cyintebe, bityo igatera amara.

Ibicuruzwa byibiribwa:

Ibiryo byangiza ibiryo hamwe na Thickener:Ikoreshwa cyane mubiribwa nka ice cream, isosi, hamwe no kwambara kugirango ibe umubyimba.

Gutekesha Gluten:Ikora nk'igisimbuza gluten, itanga imiterere nuburyo bwimigati idafite gluten, pasta, nibindi bicuruzwa bitetse.

Ibikomoka ku bimera n'ibikomoka ku bimera:HPMC ikoreshwa nkigihingwa gishingiye kuri gelatine mubiribwa bimwe na bimwe.

Amavuta yo kwisiga n'ibicuruzwa byawe bwite:

Umubyimba:HPMC ikunze kuboneka mumavuta yo kwisiga, shampo, na cream aho ifasha kunoza imiterere no gutuza kwibicuruzwa.

Ibikoresho bitanga amazi:Ikoreshwa mumazi meza kubera ubushobozi bwayo bwo kugumana amazi no kwirinda gukama.

Imikoreshereze y'inganda:

Irangi hamwe n'ibifuniko:Bitewe nuburyo bugumana amazi nogukora firime, HPMC nayo ikoreshwa mugushushanya amarangi.

Ingaruka za Hydroxypropyl Methylcellulose kumubiri:

HPMC ifatwa nk’umutekano muke wo kuyikoresha, kandi imikoreshereze yayo igengwa n’inzego zinyuranye z’ubuzima, harimo n’ikigo cy’Amerika gishinzwe ibiryo n’ibiyobyabwenge (FDA) n’ikigo cy’uburayi gishinzwe umutekano w’ibiribwa (EFSA). Mubisanzwe bifatwa nk aGRAS(Mubisanzwe bizwi nkumutekano) ibintu, cyane cyane iyo bikoreshwa mubiribwa na farumasi.

Ariko, ingaruka zayo kumubiri ziratandukanye ukurikije inzira yubuyobozi hamwe nibitekerezo birimo. Hasi aha harambuye ibisobanuro birambuye byingaruka zumubiri.

Ingaruka Zifungura Sisitemu

Ingaruka mbi:HPMC ikoreshwa mubicuruzwa bimwe na bimwe birenze urugero, cyane cyane kubantu barwaye igogora. Ikora mukunyunyuza amazi mumara, yoroshya intebe kandi ikongera ubwinshi bwayo. Ijwi ryiyongereye rifasha gukurura amara, byoroshye kunyura kuntebe.

Ubuzima bwigifu:Nkibintu bisa na fibre, AnxinCel®HPMC irashobora gushyigikira ubuzima bwigifu muri rusange mukomeza guhora. Irashobora kandi gufasha gucunga ibintu nka syndrome de munda (IBS) itanga uburuhukiro bwo kuribwa mu nda cyangwa impiswi, bitewe na formulaire.

Nyamara, ibipimo byinshi bishobora gutera kubyimba cyangwa gaze kubantu bamwe. Ni ngombwa gukomeza hydrasiyo ikwiye mugihe ukoresheje ibicuruzwa bishingiye kuri HPMC kugirango wirinde ibishobora kubaho.

Ingaruka za Metabolic na Absorption

Buhoro Absorption yibintu bifatika:Muri farumasi igenzurwa-irekura, HPMC ikoreshwa mugutinda kwinjiza ibiyobyabwenge. Ibi ni ingirakamaro cyane cyane mugihe hagomba kurekurwa imiti ihoraho kugirango imiti igabanya ubukana mu maraso.

Kurugero, imiti yububabare cyangwa antidepressants muburyo bwagutse-burekura akenshi bakoresha HPMC kugirango barekure ibiyobyabwenge gahoro gahoro, birinda impinga ninkomoko byihuse byibanda kumiti bishobora gutera ingaruka cyangwa kugabanya ingaruka.

Ingaruka ku Gutunga Intungamubiri:Nubwo muri rusange HPMC ifatwa nkuburumbuke, irashobora gutinza gato kwinjiza intungamubiri zimwe cyangwa izindi mikorere ikora iyo ikoreshejwe ari myinshi. Mubisanzwe ntabwo bihangayikishijwe nibiribwa bisanzwe cyangwa imiti ikoreshwa ariko birashobora kuba ngombwa kwitondera mugihe cyo gukoresha HPMC ikabije.

Uruhu na Topical Porogaramu

Imikoreshereze yibanze mu kwisiga:HPMC isanzwe ikoreshwa mukuvura uruhu no kwisiga kugirango ishobore kubyimba, gutuza, no gukora inzitizi kuruhu. Bikunze kuboneka mumavuta, amavuta yo kwisiga, hamwe na masike yo mumaso.

Nkibintu bidatera uburakari, bifite umutekano mubwoko bwinshi bwuruhu, harimo nuruhu rworoshye, kandi bigira akamaro muguhindura uruhu mugutega ubushuhe. Nta ngaruka zifatika zifatika iyo HPMC ishyizwe kuruhu, kuko itinjira cyane muri dermis.

Gukiza ibikomere:Ubushakashatsi bumwe bwerekanye ko HPMC ishobora kugirira akamaro gukira ibikomere. Ubushobozi bwayo bwo gukora firime imeze nka gel irashobora gufasha mukurema ibidukikije bitose byo gukira ibikomere, kugabanya inkovu no guteza imbere gukira vuba.

Ingaruka Zishobora Kuruhande

Indwara ya Gastrointestinal:Nubwo bidasanzwe, kunywa cyane HPMC bishobora gutera uburibwe bwo munda, harimo kubyimba, gaze, cyangwa impiswi. Ibi birashoboka cyane iyo bikoreshejwe cyane, cyangwa niba umuntu ku giti cye yunvikana cyane nibintu bisa na fibre.

Imyitwarire ya allergie:Mubihe bidasanzwe, abantu bamwe bashobora guhura na allergique kuri HPMC, harimo kurwara, guhinda, cyangwa kubyimba. Niba uhuye nibi bimenyetso, ni ngombwa guhagarika gukoresha ibicuruzwa no kubaza abashinzwe ubuzima.

Incamake: Hydroxypropyl Methylcellulose mu mubiri

Hydroxypropyl methylcelluloseni ibintu byinshi, bidafite uburozi bikoreshwa muburyo butandukanye, kuva muri farumasi kugeza kubicuruzwa. Iyo ukoresheje cyangwa ushyizwe hejuru, bigira ingaruka nziza kumubiri, cyane cyane nkibibyimbye, stabilisateur, cyangwa binder. Gukoresha imiti igenzurwa-irekura imiti ifasha kugenzura iyinjizwa ryibintu bikora, mugihe inyungu zayo zifungura zigaragara cyane cyane mubikorwa byayo nk'inyongeramusaruro cyangwa fibre. Irashobora kandi kugira ingaruka nziza kubuzima bwuruhu iyo ikoreshejwe muburyo bukomeye.

Ariko rero, ni ngombwa kuyikoresha ukurikije ibipimo ngenderwaho hamwe nubuyobozi kugirango wirinde ingaruka nko kubyimba cyangwa gastrointestinal. Muri rusange, iyo ikoreshejwe neza, AnxinCel®HPMC ifatwa nkumutekano kandi ifite akamaro mubikorwa bitandukanye no mubikorwa.

Imbonerahamwe: Ingaruka za Hydroxypropyl Methylcellulose (HPMC)