1. Ibintu shingiro bya HPMC
Hydroxypropyl methylcellulose (HPMC)ni selile nonionic selulose ether ikoreshwa cyane mubikoresho byubwubatsi, ubuvuzi, ibiryo, amavuta yo kwisiga nizindi nganda. Imiterere yihariye ya fiziki-chimique, nko gukemuka, kubyimba, gukora firime hamwe nubushyuhe bwumuriro, bituma iba ikintu cyingenzi mubikorwa byinshi byinganda. Ubushyuhe ni kimwe mu bintu by'ingenzi bigira ingaruka ku mikorere ya HPMC, cyane cyane mu bijyanye no gukemuka, ubukonje, ubushyuhe bw’umuriro hamwe n’ubushyuhe bw’umuriro.
2. Ingaruka yubushyuhe kumashanyarazi ya HPMC
HPMC ni polymer yubushyuhe bukabije, kandi ibisubizo byayo bihinduka hamwe nubushyuhe:
Ubushyuhe buke (amazi akonje): HPMC irashobora gushonga byoroshye mumazi akonje, ariko izakurura amazi ikabyimba mugihe ihuye nambere namazi kugirango ibe uduce duto twa gel. Niba gukurura bidahagije, ibibyimba birashobora gukora. Kubwibyo, mubisanzwe birasabwa kongeramo HPMC gahoro gahoro mugihe utera imbere gutatanya kimwe.
Ubushyuhe bwo hagati (20-40 ℃): Muri ubu bushyuhe, HPMC ifite imbaraga zo gukomera no kwiyegereza cyane, kandi ikwiranye na sisitemu zitandukanye zisaba kubyimba cyangwa guhagarara neza.
Ubushyuhe bwo hejuru (hejuru ya 60 ° C): HPMC ikunda gukora gel ishyushye mubushyuhe bwinshi. Iyo ubushyuhe bugeze ku bushyuhe bwihariye bwa gel, igisubizo kizahinduka neza cyangwa se coagulite, bigira ingaruka kubikorwa. Kurugero, mubikoresho byubaka nka minisiteri cyangwa ifu ya putty, niba ubushyuhe bwamazi buri hejuru cyane, HPMC ntishobora gushonga neza, bityo bikagira ingaruka kumyubakire.
3. Ingaruka yubushyuhe kuri HPMC
Ubukonje bwa HPMC bugira ingaruka cyane kubushyuhe:
Kongera ubushyuhe, kugabanya ubukonje: Ubukonje bwumuti wa HPMC mubusanzwe bugabanuka hamwe nubushyuhe bwiyongera. Kurugero, ubwiza bwumuti runaka wa HPMC burashobora kuba hejuru kuri 20 ° C, mugihe kuri 50 ° C, ububobere bwabwo buzagabanuka cyane.
Ubushyuhe buragabanuka, viscosity irakira: Niba igisubizo cya HPMC gikonje nyuma yo gushyuha, ububobere bwacyo buzakira igice, ariko ntibishobora gusubira rwose muburyo bwambere.
HPMC yo mu byiciro bitandukanye byo kwifata yitwara mu buryo butandukanye: ubukonje bwinshi HPMC yunvikana cyane n’imihindagurikire y’ubushyuhe, mu gihe ubukonje buke HPMC ifite ihindagurika rike cyane iyo ubushyuhe buhindutse. Kubwibyo, ni ngombwa cyane guhitamo HPMC hamwe nubwiza bukwiye muburyo butandukanye bwo gusaba.
4. Ingaruka yubushyuhe kumashanyarazi ya HPMC
Ikintu cyingenzi kiranga HPMC ni ubushyuhe bwumuriro, ni ukuvuga, iyo ubushyuhe buzamutse kurwego runaka, igisubizo cyacyo kizahinduka gel. Ubu bushyuhe ubusanzwe bwitwa ubushyuhe bwa gelation. Ubwoko butandukanye bwa HPMC bufite ubushyuhe butandukanye, muri rusange hagati ya 50-80 ℃.
Mu nganda z’ibiribwa n’imiti, ibi biranga HPMC bikoreshwa mugutegura imiti irekura cyangwa irekuye ibiryo.
Mubikorwa byubwubatsi, nka sima ya pome nifu ya putty, ubushyuhe bwumuriro wa HPMC burashobora gutanga amazi, ariko niba ubushyuhe bwibidukikije bwubatswe ari bwinshi, gelation irashobora kugira ingaruka kubikorwa byubwubatsi.
5. Ingaruka yubushyuhe kumashanyarazi ya HPMC
Imiterere yimiti ya HPMC irahagaze neza mubipimo byubushyuhe bukwiye, ariko kumara igihe kinini guhura nubushyuhe bwo hejuru bishobora gutera kwangirika.
Ubushyuhe bwo hejuru bwigihe gito (nko gushyushya ako kanya kugeza hejuru ya 100 ℃): ntibishobora kugira ingaruka zikomeye kumiterere ya chimique ya HPMC, ariko birashobora gutera impinduka mumiterere yumubiri, nko kugabanuka kwijimye.
Ubushyuhe burebure bwigihe kirekire (nkubushyuhe bukomeza hejuru ya 90 ℃): bushobora gutuma urunigi rwa molekile ya HPMC rucika, bigatuma igabanuka ryidasubirwaho ryijimye, bikagira ingaruka kubyimbye no gukora firime.
Ubushyuhe bukabije cyane (hejuru ya 200 ℃): HPMC irashobora kwangirika k'ubushyuhe, ikarekura ibintu bihindagurika nka methanol na propanol, kandi bigatuma ibikoresho bihinduka ibara cyangwa ndetse na karubone.
6. Gusaba ibyifuzo bya HPMC mubidukikije bitandukanye
Kugirango utange umukino wuzuye kumikorere ya HPMC, hagomba gufatwa ingamba zikwiye ukurikije ubushyuhe butandukanye:
Mu bushyuhe buke (0-10 ℃): HPMC ishonga buhoro, kandi birasabwa kubanza kuyishonga mumazi ashyushye (20-40 ℃) mbere yo kuyakoresha.
Mubihe bisanzwe byubushyuhe (10-40 ℃): HPMC ifite imikorere ihamye kandi irakwiriye mubisabwa byinshi, nka coatings, minisiteri, ibiryo nibikomoka kumiti.
Mubushyuhe bwo hejuru (hejuru ya 40 ℃): Irinde kongeramo HPMC mumazi yubushyuhe bwo hejuru. Birasabwa kuyishonga mumazi akonje mbere yo kuyashyushya, cyangwa guhitamo HPMC irwanya ubushyuhe bwinshi kugirango ugabanye ingaruka ziterwa nubushyuhe bwa porogaramu.
Ubushyuhe bugira ingaruka zikomeye kumashanyarazi, ubukonje, ubushyuhe bwumuriro hamwe nubushyuhe bwaHPMC. Mugihe cyo gusaba, birakenewe guhitamo muburyo bwuburyo nuburyo bwo gukoresha HPMC ukurikije ubushyuhe bwihariye kugirango tumenye neza. Gusobanukirwa n'ubushyuhe bwa HPMC ntibishobora kuzamura ubwiza bwibicuruzwa gusa, ariko kandi birinda igihombo kidakenewe cyatewe nihindagurika ryubushyuhe no kuzamura umusaruro n’inyungu zubukungu.
Igihe cyo kohereza: Werurwe-28-2025