Hydroxypropyl MethylcelluloseA nkọwa zuru oke

Hydroxypropyl methylcellulose (HPMC)bụ polymer dị iche iche nke na-achọta ngwa ngwa n'ọtụtụ ọrụ dị iche iche, gụnyere ọgwụ, nri, ihe owuwu na ihe ịchọ mma. Ngwakọta a, nke sitere na cellulose, na-enye ihe pụrụ iche dị ka ịgbakọ, njide, imepụta ihe nkiri, na ntọhapụ na-adịgide adịgide.

1. Ọdịdị na Njirimara

HPMC bụ ọkara sịntetik, polymer soluble mmiri nke sitere na cellulose. A na-ejikọta ya site na iji propylene oxide na methyl chloride na-agwọ cellulose, na-ebute mgbanwe nke hydroxyl otu hydroxypropyl na methoxy otu. Ogo nke nnọchi (DS) nke otu ndị a dịgasị iche, na-emetụta njirimara nke HPMC.

Ọnụnọ nke hydroxypropyl na methoxy otu na-enye HPMC ọtụtụ ihe dị mkpa:

Mmiri solubility: HPMC bụ soluble na mmiri oyi, na-akpụ a doro anya, viscous ngwọta. Solubility na-adabere n'ihe ndị dị ka DS, arọ molekụla, na okpomọkụ.

Ịme ihe nkiri: HPMC nwere ike ịmepụta ihe nkiri na-agbanwe agbanwe, nke na-enweghị atụ mgbe a na-ese ya na ngwọta mmiri. Ihe nkiri ndị a na-achọta ngwa na mkpuchi ọgwụ, matrices ntọhapụ a na-achịkwa, na ihe nkiri oriri na ụlọ ọrụ nri.

Thickening: HPMC ngwọta na-egosipụta pseudoplastic omume, ebe viscosity na-ebelata na-abawanye shiee ọnụ ọgụgụ. Ngwongwo a na-eme ka ọ dị mma maka iji ya dị ka ihe na-eme ka ọ sie ike n'ụdị dị iche iche, gụnyere agba, nrapado, na ngwaahịa nlekọta onwe onye.

Ntọhapụ na-adịgide adịgide: N'ihi ọzịza ya na ihe mbuze ya, HPMC na-arụ ọrụ n'ọtụtụ ebe na sistemụ nnyefe ọgwụ na-adịgide adịgide. Enwere ike ịhazi ọnụego mwepụta ọgwụ site na ịhazigharị mkpokọta polymer, DS, na usoro nhazi ndị ọzọ.

2. Synthesis

Ngwakọta nke HPMC gụnyere ọtụtụ usoro:

Etherification: A na-emeso cellulose na ngwakọta nke propylene oxide na alkali, na-ebute iwebata otu hydroxypropyl.

Methylation: A na-eji methyl chloride meghachi omume na cellulose hydroxypropylated iji webata otu methoxy.

Enwere ike ịchịkwa ogo ngbanwe site na ịhazigharị ọnọdụ mmeghachi omume, dị ka oke nke reagents, oge mmeghachi omume, na okpomọkụ. Ụkpụrụ DS dị elu na-eduga n'ịba ụba hydrophilicity na solubility nke HPMC.

3. Ngwa

HPMC na-achọta ngwa zuru ebe niile n'ofe ụlọ ọrụ dị iche iche:

Pharmaceuticals: N'ime usoro ọgwụ, HPMC na-eje ozi dị ka onye na-ekekọta, disintegrant, mkpuchi mkpuchi, na matriks nke bụbu n'ụdị usoro ntọhapụ a na-achịkwa. A na-eji ya eme ihe na mbadamba nkume, capsules, nkwadebe ophthalmic, na nhazi usoro.

Nri: A na-eji HPMC eme ihe na ngwaahịa nri dị ka onye na-agbapụta, stabilizer, emulsifier, na onye na-emepụta ihe nkiri. Ọ na-eme ka udidi, mmetụta ọnụ, na nkwụsi ike shelf dị na ngwaahịa ndị dị ka sos, ofe, desserts, na ngwa esi nri.

Ihe owuwu: N'ihe owuwu ụlọ, HPMC na-arụ ọrụ dị ka ihe na-ejigide mmiri, ihe na-ekpu mmiri, na rheology modifier n'ime ụrọ ndị dabeere na ciment, adhesives tile, plasters, na gypsum ngwaahịa. Ọ na-eme ka arụmọrụ rụọ ọrụ, adhesion, na oge oghe nke usoro ndị a.

Ihe ịchọ mma: A na-etinye HPMC n'ime ihe ịchọ mma na ngwaahịa nlekọta onwe onye dị ka onye na-agba agba, ihe nkiri mbụ, na emulsifier na ude, lotions, shampoos na mascaras. Ọ na-enye udidi dị nro, nkwụsi ike, na ntọhapụ a na-achịkwa nke ihe ndị na-arụ ọrụ.

Ụlọ ọrụ ndị ọzọ: HPMC na-arụkwa ọrụ na mbipụta textiles, mkpuchi akwụkwọ, ncha, na nhazi ọrụ ugbo n'ihi ihe ndị dị na ya.

4. Atụmanya Ọdịnihu

A na-atụ anya na ọchọrọ HPMC ga-eto nke ukwuu n'afọ ndị na-abịa, nke ọtụtụ ihe kpatara:

Ihe ohuru ohuru nke ọgwụ: Site na nlebara anya na-abawanye na sistemu nnyefe ọgwụ ọhụrụ yana ọgwụ ahaziri onwe ya, usoro dabere na HPMC nwere ike ịhụ mmepe na-aga n'ihu. Teknụzụ mwepụta a na-achịkwa, nanomedicine, na ọgwụgwọ ngwakọta na-enye ụzọ dị mma maka ngwa HPMC.

Green Chemistry Initiatives: Ka nchegbu gburugburu ebe obibi na-abawanye, enwere mmasị na-eto eto maka ihe omume enyi na enyi na ndụ. HPMC, ewepụtara site na isi mmalite cellulose mmeghari, kwekọrọ na ebumnuche nkwado ma dị njikere iji dochie polymers sịntetik n'ọtụtụ ngwa.

Usoro nrụpụta dị elu: Ọganihu na injinia usoro, kemịkalụ polymer, na nanotechnology na-enyere aka imepụta HPMC nwere ihe ahaziri ahazi yana arụmọrụ ka mma. Mwepụta Nanocellulose, ihe ndị mejupụtara, na usoro obibi akwụkwọ 3D nwere ikike ịgbasa ụdịdị ngwa ngwa nke HPMC.

Okirikiri ala na-achịkwa: Ụlọ ọrụ na-achịkwa na-etinye ụkpụrụ nduzi siri ike na iji polymers na ụlọ ọrụ dị iche iche, karịsịa na ọgwụ na nri. Nrube isi na nchekwa, ịdịmma, na mkpa akara ga-adị mkpa maka ndị nrụpụta na ndị na-emepụta ihe na-ejiHPMCna ngwaahịa ha.

hydroxypropyl methylcellulose (HPMC) pụtara dị ka polymer na-agbanwe agbanwe nwere ngwa dị iche iche n'ofe ọgwụ, nri, ihe owuwu, ihe ịchọ mma, na ụlọ ọrụ ndị ọzọ. Ngwongwo ya pụrụ iche, gụnyere solubility mmiri, ikike imepụta ihe nkiri, ime ihe siri ike, na ikike ntọhapụ na-adịgide adịgide, na-eme ka ọ dị mkpa n'ụdị dị iche iche. Site na nyocha na-aga n'ihu, ọganihu nkà na ụzụ, na ịmawanye mmata maka nkwado, HPMC dị njikere ịrụ nnukwu ọrụ n'ịkpụzi ihe n'ọdịnihu na mmepụta ihe ọhụrụ.