Ịghọta Hydroxypropyl Methyl Cellulose (HPMC)
Hydroxypropyl Methyl Cellulose (HPMC) bụ polymer vasatail eji eme ihe n'ọtụtụ ụlọ ọrụ dị iche iche, gụnyere ọgwụ, nri, ihe ịchọ mma na ihe owuwu. Njirimara ya pụrụ iche, dị ka mmiri solubility, gelation on kpo oku, na ike imepụta ihe nkiri, na-eme ka ọ bụrụ ihe bara uru n'ọtụtụ nhazi. Otu n'ime ihe ndị dị oke egwu nke HPMC bụ viscosity ya, nke na-emetụta ọrụ ya na ngwa ya.
Ihe ndị na-emetụta viscosity nke HPMC
Ọtụtụ ihe na-emetụta viscosity nke HPMC, gụnyere:
Ibu Molecular: Akara ule HPMC dị elu na-egosipụtakarị viscosity dị elu.
Ntinye uche: viscosity na-abawanye na ntinye nke HPMC na ngwọta.
Okpomọkụ: Viscosity na-ebelata na okpomọkụ na-abawanye n'ihi ụdọ polymer na-aghọwanye mkpanaka.
pH: HPMC kwụsiri ike gafee oke pH, mana oke pH nwere ike imetụta viscosity.
Degree of Substitution (DS) na Molar Substitution (MS): Ogo nke nnọchi (ọnụọgụ nke hydroxyl otu nke methoxy ma ọ bụ hydroxypropyl nọchiri anya) na molar nnọchi (ọnụọgụ hydroxypropyl otu otu glucose unit) na-emetụta solubility na viscosity nke HPMC.
Viscosity kwesịrị ekwesị maka ngwa dị iche iche
Viscosity kwesịrị ekwesị nke HPMC dabere na ngwa a kapịrị ọnụ. Nke a bụ nlele zuru ezu ka ihe achọrọ viscosity si dị iche na ụlọ ọrụ dị iche iche:
1. Ọgwụ ọgwụ
N'ọgwụ ọgwụ, a na-eji HPMC dịka ihe nkedo, onye na-eme ihe nkiri na onye na-ewepụta ihe na-achịkwa ya na mbadamba na capsules.
Mbadamba ụrọ: HPMC dị ala na ọkara viscosity (3-5% ngwọta na 50-100 cps) dabara maka mkpuchi ihe nkiri, na-enye oyi akwa dị nro.
Mwepụta a na-achịkwa: A na-eji HPMC viscosity dị elu (ihe ngwọta 1% nwere 1,500-100,000 cps) na mbadamba matriks iji chịkwaa ọnụego ntọhapụ nke ihe na-arụ ọrụ, na-eme ka ntọhapụ na-adịgide adịgide ka oge na-aga.
Ihe na-ekekọta na granulation: HPMC viscosity ọkara (2% ngwọta na 400-4,000 cps) bụ ọkacha mmasị maka usoro mmiri granulation iji mepụta granules nwere ike ọrụ dị mma.
2. Ụlọ ọrụ nri
N'ime ụlọ ọrụ nri, a na-eji HPMC eme ihe dị ka ihe na-agbapụta, stabilizer, na emulsifier.
Ihe na-eme ka ọ dị arọ: A na-eji HPMC viscosity dị ala ma ọ bụ nke ọkara (ihe ngwọta 1-2% nwere 50-4,000 cps) iji mee ka nri, uwe, na ofe sie ike.
Emulsifier na Stabilizer: HPMC viscosity dị ala (1% ngwọta na 10-50 cps) dabara maka ịkwado emulsions na foams, na-enye udidi a na-achọsi ike na ngwaahịa dị ka ice cream na toppings.
3. Ihe ịchọ mma na nlekọta onwe onye
A na-eji HPMC eme ihe na ihe ịchọ mma maka ihe na-eme ka ọ sie ike, na-emepụta ihe nkiri na nke na-eme ka mmiri dị nro.
Ude na ude: HPMC viscosity dị ala na ọkara (ihe ngwọta 1% nwere 50-4,000 cps) na-enye nkwụsi ike na nkwụsi ike achọrọ.
Ngwaahịa Nlekọta ntutu: A na-eji HPMC viscosity ọkara (ihe ngwọta 1% nwere 400-4,000 cps) na shampoos na conditioners iji meziwanye ọdịdị na arụmọrụ.
4. Ụlọ ọrụ mmepụta ihe
N'ime ihe owuwu, HPMC bụ ihe dị mkpa na ngwaahịa dị ka nrapado tile, plasta, na ihe ndị sitere na ciment.
Tile Adhesives and Grouts: Ọkara na viscosity HPMC dị elu (2% ngwọta na 4,000-20,000 cps) na-eme ka arụ ọrụ dịkwuo mma, njide mmiri, na ihe nkwekọ.
Plasters ciment: Ọkara viscosity HPMC (1% ngwọta na 400-4,000 cps) na-eme ka njide mmiri na ịrụ ọrụ, na-egbochi mgbawa na imezi njedebe.
Nleta viscosity na ụkpụrụ
A na-atụkarị viscosity nke HPMC site na iji viscometer, a na-egosipụtakwa nsonaazụ ya na centipoise (cps). A na-eji usoro ọkọlọtọ dị ka Brookfield viscometry ma ọ bụ viscometry capillary dabere na oke viscosity. Nhọrọ nke ọkwa kwesịrị ekwesị nke HPMC na-eduzi site na nkọwapụta nke ndị nrụpụta nyere, nke gụnyere profaịlụ viscosity zuru ezu.
Echiche bara uru
Mgbe ị na-ahọrọ HPMC maka otu ngwa, ekwesịrị iburu n'uche ọtụtụ ihe bara uru:
Nkwadebe ngwọta: hydration kwesịrị ekwesị na mgbasa dị oke mkpa maka imezu viscosity achọrọ. Nke nta nke nta na-agbakwunye na mmiri na-aga n'ihu na-akpali akpali na-enyere aka igbochi ọkpụkpụ akpụ.
Ndakọrịta: Ekwesịrị ịnwale ndakọrịta nke HPMC yana ihe nhazi ndị ọzọ iji hụ na nkwụsi ike na ịdị mma.
Ọnọdụ Nchekwa: Enwere ike imetụta viscosity site na ọnọdụ nchekwa dị ka okpomọkụ na iru mmiri. Nchekwa kwesịrị ekwesị na ebe dị jụụ, nke kpọrọ nkụ dị mkpa iji nọgide na-enwe àgwà HPMC.
Viscosity kwesịrị ekwesị nke Hydroxypropyl Methyl Cellulose (HPMC) dịgasị iche dabere na ngwa a, sitere na viscosity dị ala maka emulsification na nkwụsi ike na ngwaahịa nri ruo elu viscosity maka mwepụta ọgwụ a na-achịkwa na ụlọ ọgwụ. Ịghọta ihe ndị a kapịrị ọnụ nke ụlọ ọrụ na ngwa ọ bụla dị oke mkpa maka ịhọrọ ọkwa ziri ezi nke HPMC, na-ahụ na arụmọrụ na ịrụ ọrụ kacha mma. Site n'ịtụle ihe ndị dị ka ịdị arọ molekụla, itinye uche, okpomọkụ, na pH, ndị na-emepụta nwere ike ịhazi ihe ngwọta HPMC iji gboo mkpa nhazi.
Oge nzipu: Mee-22-2024