Hydroxypropyl Methylcellulose (HPMC)yog ib hom tshuaj hloov kho ntawm cellulose uas tau siv dav hauv ntau yam kev lag luam xws li tshuaj, khoom noj khoom haus, thiab kev tsim kho. Nws yog ntau yam sib xyaw, feem ntau siv los ua cov thickener, binder, film-forming agent, thiab stabilizer. Txawm li cas los xij, nws tsis muaj qhov tshwj xeeb "serial tooj" hauv qhov kev xav ib txwm muaj, zoo li cov khoom lag luam lossis tus lej koj tuaj yeem pom hauv lwm cov ntsiab lus tsim khoom. Hloov chaw, HPMC tau txheeb xyuas los ntawm nws cov qauv tshuaj thiab ntau tus yam ntxwv, xws li qib kev hloov pauv thiab viscosity.
Cov ntaub ntawv dav dav txog Hydroxypropyl Methylcellulose (HPMC)
Chemical Structure: HPMC yog tsim los ntawm chemically modifying cellulose los ntawm kev hloov ntawm hydroxyl (-OH) pawg nrog hydroxypropyl thiab methyl pawg. Kev hloov pauv hloov cov khoom ntawm cellulose, ua rau nws ntau soluble hauv dej thiab muab nws cov khoom tshwj xeeb xws li kev txhim kho zaj duab xis-tsim muaj peev xwm, khi muaj peev xwm, thiab muaj peev xwm khaws cov dej noo.
Common Identifiers thiab Nameing
Kev txheeb xyuas ntawm Hydroxypropyl Methylcellulose feem ntau yog nyob ntawm ntau hom npe cov cai uas piav txog nws cov qauv tshuaj thiab cov khoom:
CAS Nr .:
Chemical Abstracts Service (CAS) muab tus cim tshwj xeeb rau txhua yam tshuaj. CAS tus lej rau Hydroxypropyl Methylcellulose yog 9004-65-3. Qhov no yog tus lej tus qauv siv los ntawm cov kws kho mob, cov chaw muag khoom, thiab cov koom haum tswj hwm kom xa mus rau cov khoom.
InChI thiab SMILES Codes:
InChI (International Chemical Identifier) yog lwm txoj hauv kev los sawv cev cov qauv tshuaj ntawm cov khoom. HPMC yuav muaj ib txoj hlua InChI ntev uas sawv cev rau nws cov qauv molecular hauv cov qauv qauv.
SMILES (Simplified Molecular Input Line Entry System) yog lwm qhov system siv los sawv cev rau cov molecules hauv daim ntawv ntawv. HPMC kuj tseem muaj qhov sib thooj SMILES code, txawm hais tias nws yuav nyuaj heev vim qhov loj thiab sib txawv ntawm nws cov qauv.
Khoom Specifications:
Hauv kev lag luam kev lag luam, HPMC feem ntau txheeb xyuas los ntawm cov khoom lag luam, uas tuaj yeem sib txawv ntawm cov chaw tsim khoom. Piv txwv li, tus neeg muag khoom yuav muaj qib zoo li HPMC K4M lossis HPMC E15. Cov cim qhia no feem ntau xa mus rau viscosity ntawm cov polymer hauv kev daws, uas yog txiav txim siab los ntawm qib ntawm methylation thiab hydroxypropylation nrog rau qhov hnyav molecular.
Qib Qib Ntawm Hydroxypropyl Methylcellulose (HPMC)
Cov yam ntxwv ntawm Hydroxypropyl Methylcellulose sib txawv raws li qib kev hloov pauv ntawm pawg methyl thiab hydroxypropyl, nrog rau qhov hnyav molecular. Cov kev hloov pauv no txiav txim siab HPMC qhov viscosity thiab solubility hauv dej, uas cuam tshuam rau nws cov kev siv hauv kev lag luam sib txawv.
Hauv qab no yog ib lub rooj uas qhia txog cov qib sib txawv ntawm Hydroxypropyl Methylcellulose:
| Qib | Viscosity (cP hauv 2% tov) | Daim ntawv thov | Kev piav qhia |
| HPMC K4M | 4000-6000 hli | Pharmaceutical tablet binder, zaub mov kev lag luam, kev tsim kho (adhesives) | Medium viscosity qib, feem ntau siv hauv cov tshuaj ntsiav tshuaj hauv qhov ncauj. |
| HPMC K100M | 100,000 - 150,000 PIB | Tswj-tso formulations nyob rau hauv kws tshuaj, kev tsim kho, thiab xim txheej | High viscosity, zoo heev rau kev tswj cov tshuaj tso tawm. |
| HPMC E4M | 3000-4500 hli | Tshuaj pleev ib ce, tshuaj ntxuav tais diav, khoom noj khoom haus, adhesives, thiab coatings | Soluble nyob rau hauv dej txias, siv nyob rau hauv cov khoom tu tus kheej thiab cov khoom noj. |
| HPMC E15 | 15,000 NP | Thickening tus neeg sawv cev hauv cov xim, txheej, khoom noj, thiab tshuaj | High viscosity, soluble hauv dej txias, siv hauv cov khoom lag luam thiab tshuaj. |
| HPMC M4C | 4000-6000 hli | Khoom noj khoom haus thiab dej haus kev lag luam raws li ib tug stabilizer, tshuaj raws li ib tug binder | Nruab nrab viscosity, feem ntau siv los ua cov thickener hauv cov zaub mov tiav. |
| TIAB SA 2910 | 3000-6000 hli | Tshuaj pleev ib ce (cream, lotions), zaub mov (confectionery), kws tshuaj (capsules, coatings) | Ib qho ntawm cov qib ntau tshaj plaws, siv los ua kom ruaj khov thiab thickening tus neeg sawv cev. |
| TIAB SA 2208 | 5000 - 15000 hli | Siv rau hauv cement thiab plaster formulations, textiles, ntawv txheej | Zoo rau cov ntawv thov uas xav tau kev ua yeeb yaj kiab zoo heev. |
Cov ncauj lus kom ntxaws thiab cov khoom ntawm HPMC
Lub cev muaj zog ntawm Hydroxypropyl Methylcellulose nyob ntawm qhov ntau ntawm kev hloov ntawm hydroxyl pawg hauv cellulose molecule. Nov yog cov khoom tseem ceeb:
Degree of Hloov (DS):
Qhov no yog hais txog pes tsawg pawg hydroxyl hauv cellulose tau hloov los ntawm methyl lossis hydroxypropyl pawg. Qib ntawm kev hloov pauv cuam tshuam rau kev solubility ntawm HPMC hauv dej, nws cov viscosity, thiab nws lub peev xwm los tsim cov yeeb yaj kiab. Cov DS ib txwm rau HPMC yog nyob ntawm 1.4 txog 2.2, nyob ntawm qib.
viscosity:
Cov qib HPMC raug cais raws li lawv cov viscosity thaum yaj hauv dej. Qhov siab dua qhov hnyav molecular thiab qib ntawm kev hloov pauv, qhov viscosity siab dua. Piv txwv li, HPMC K100M (nrog cov viscosity ntau dua) feem ntau yog siv los tswj-tso tshuaj formulations, whereas qis viscosity qib zoo li HPMC K4M feem ntau yog siv rau cov ntsiav tshuaj binders thiab daim ntawv thov zaub mov.
Dej Solubility:
HPMC yog soluble hauv dej thiab tsim cov khoom zoo li gel thaum yaj, tab sis qhov kub thiab pH tuaj yeem cuam tshuam nws cov solubility. Piv txwv li, nyob rau hauv dej txias, nws dissolves sai, tab sis nws solubility yuav txo tau nyob rau hauv dej kub, tshwj xeeb tshaj yog nyob rau hauv ntau dua concentrations.
Film-Forming Muaj peev xwm:
Ib qho ntawm cov yam ntxwv tseem ceeb ntawm Hydroxypropyl Methylcellulose yog nws lub peev xwm los tsim ib zaj duab xis hloov tau. Cov cuab yeej no ua rau nws tsim nyog siv rau hauv cov ntsiav tshuaj coatings, qhov twg nws muab ib tug du, tswj-tso nto. Nws kuj tseem muaj txiaj ntsig zoo hauv kev lag luam khoom noj los txhim kho kev ntxhib los mos thiab txee lub neej.
Gelation:
Ntawm qee qhov siab thiab qhov kub thiab txias, HPMC tuaj yeem tsim cov gels. Cov cuab yeej no muaj txiaj ntsig zoo hauv cov tshuaj formulations, qhov twg nws yog siv los tsim kev tswj-tso systems.
Kev siv ntawm Hydroxypropyl Methylcellulose
Pharmaceutical Industry:
HPMC yog siv los ua cov ntaub ntawv hauv cov ntsiav tshuaj, tshwj xeeb tshaj yog nyob rau hauv kev ncua-tso thiab tswj-tso systems. Nws kuj ua hauj lwm raws li tus neeg sawv cev txheej rau cov ntsiav tshuaj thiab tshuaj ntsiav los tswj kev tso tawm ntawm cov khoom xyaw nquag. Nws lub peev xwm los tsim cov yeeb yaj kiab ruaj khov thiab cov gels yog qhov zoo tagnrho rau kev xa tshuaj.
Kev lag luam zaub mov
Hauv kev lag luam khoom noj khoom haus, HPMC yog siv los ua tus neeg sawv cev thickening, emulsifier, thiab stabilizer hauv ntau yam khoom, nrog rau cov kua ntses, hnav khaub ncaws, thiab cov khoom ci. Nws pab txhim kho kev ntxhib los mos thiab txuas lub neej txee los ntawm kev txo cov dej noo.
Tshuaj pleev ib ce thiab kho tus kheej:
HPMC yog siv dav hauv cov tshuaj pleev ib ce, qhov chaw uas nws ua cov thickener thiab stabilizer hauv cov tshuaj pleev, tshuaj pleev, tshuaj zawv plaub hau, thiab lwm yam khoom siv tu tus kheej. Nws lub peev xwm los tsim cov qauv gel yog qhov tseem ceeb hauv cov ntawv thov no.
Kev tsim kho kev lag luam:
Hauv kev tsim kho kev lag luam, tshwj xeeb tshaj yog nyob rau hauv cov cement thiab plaster formulations, HPMC yog siv los ua tus neeg saib xyuas dej. Nws pab txhim kho kev ua haujlwm thiab txhim kho cov khoom sib txuas ntawm cov khoom.
Lwm yam kev siv:
HPMC tseem ua haujlwm hauv kev lag luam textile, ntawv txheej, thiab txawm tias hauv kev tsim cov yeeb yaj kiab biodegradable.
Hydroxypropyl Methylcellulose (HPMC)yog ib qho kev sib xyaw ua ke uas muaj ntau yam siv thoob plaws ntau qhov kev lag luam vim nws cov khoom tshwj xeeb xws li kev ua yeeb yaj kiab, muaj peev xwm thickening, thiab tuav dej. Txawm hais tias nws tsis muaj "serial tooj" hauv qhov kev nkag siab zoo, nws raug txheeb xyuas los ntawm cov cim tshuaj lom neeg xws li nws tus lej CAS (9004-65-3) thiab cov khoom tshwj xeeb (xws li HPMC K100M, HPMC E4M). Muaj ntau hom HPMC qib muaj ua kom nws muaj feem xyuam rau ntau qhov chaw, los ntawm cov kws tshuaj mus rau zaub mov, tshuaj pleev ib ce, thiab kev tsim kho.
Lub sij hawm xa tuaj: Mar-21-2025