Hydroxypropyl methylcellulose (HPMC) yog ib qho tshuaj ntxiv tseem ceeb, siv dav hauv ntau qhov chaw xws li kev tsim kho, tshuaj, khoom noj, thiab tshuaj pleev ib ce. Nws muaj cov khoom zoo thickening, gelling, emulsifying, zaj duab xis-tsim, thiab kev sib txuas, thiab muaj qee qhov kev ruaj khov rau qhov kub thiab pH. Qhov solubility ntawm HPMC yog ib qho ntawm cov teeb meem tseem ceeb hauv nws siv. Kev nkag siab txog txoj kev yaj kom raug yog qhov tseem ceeb kom ntseeg tau tias nws ua haujlwm tau zoo.
1. Cov khoom siv yooj yim ntawm HPMC
Hydroxypropyl methylcellulose yog cov cellulose ether uas tsis yog ionic uas yaj tau hauv dej uas tuaj yeem yaj rau hauv dej txias lossis dej kub kom ua tau cov kua nplaum pob tshab lossis pob tshab. Nws qhov solubility feem ntau cuam tshuam los ntawm qhov kub thiab txias. Nws yooj yim dua rau yaj rau hauv dej txias thiab yooj yim rau tsim cov colloid hauv dej kub. HPMC muaj thermal gelation, uas yog, nws muaj solubility tsis zoo ntawm qhov kub siab dua, tab sis tuaj yeem yaj tag nrho thaum qhov kub qis dua. HPMC muaj qhov hnyav molecular thiab viscosities sib txawv, yog li thaum lub sijhawm yaj, tus qauv HPMC tsim nyog yuav tsum tau xaiv raws li cov khoom xav tau.
2. Txoj kev yaj ntawm HPMC
Txoj kev faib dej txias
Txoj kev sib xyaw dej txias yog txoj kev sib xyaw HPMC feem ntau siv thiab tsim nyog rau feem ntau ntawm cov xwm txheej thov. Cov kauj ruam tshwj xeeb yog raws li nram no:
Npaj dej txias: Ncuav cov dej txias uas xav tau rau hauv lub thawv sib tov. Feem ntau pom zoo kom qhov kub ntawm dej qis dua 40 ° C kom tsis txhob muaj HPMC ua pob thaum kub siab.
Maj mam ntxiv HPMC: Maj mam ntxiv hmoov HPMC thiab txuas ntxiv do. Yuav kom tsis txhob muaj hmoov sib xyaw, yuav tsum siv qhov ceev do kom zoo kom ntseeg tau tias HPMC tuaj yeem sib xyaws hauv dej.
Sawv thiab yaj: Tom qab HPMC raug yaj hauv dej txias, nws yuav tsum sawv rau ib lub sijhawm kom yaj tag. Feem ntau, nws raug tso rau 30 feeb txog ob peb teev, thiab lub sijhawm tshwj xeeb sib txawv nyob ntawm tus qauv HPMC thiab qhov kub ntawm dej. Thaum lub sijhawm sawv, HPMC yuav maj mam yaj los ua cov kua nplaum.
Txoj kev ua ntej yaj dej kub
Txoj kev ua ntej yaj dej kub yog qhov tsim nyog rau qee cov qauv HPMC uas muaj viscosity siab lossis nyuaj rau yaj tag nrho hauv dej txias. Txoj kev no yog thawj zaug sib tov cov hmoov HPMC nrog ib feem ntawm cov dej kub kom ua ib qho nplaum, thiab tom qab ntawd sib tov nrog dej txias kom thaum kawg tau txais cov tshuaj sib xws. Cov kauj ruam tshwj xeeb yog raws li nram no:
Ua kom dej kub: Ua kom ib qho dej kub txog li 80°C thiab nchuav rau hauv lub thawv sib tov.
Ntxiv hmoov HPMC: Ncuav hmoov HPMC rau hauv dej kub thiab do thaum nchuav kom sib tov ua ib qho nplaum. Hauv dej kub, HPMC yuav yaj ib ntus thiab tsim cov tshuaj zoo li gel.
Ntxiv dej txias kom yaj: Tom qab cov khoom sib tov txias lawm, maj mam ntxiv dej txias kom yaj thiab txuas ntxiv do kom txog thaum nws yaj tag rau hauv cov kua pob tshab lossis pob tshab.
Txoj kev faib cov kuab tshuaj organic
Qee zaum, txhawm rau kom ua kom HPMC yaj sai dua lossis txhim kho qhov cuam tshuam ntawm qee yam kev siv tshwj xeeb, cov kuab tshuaj organic tuaj yeem siv los sib tov nrog dej kom yaj HPMC. Piv txwv li, cov kuab tshuaj organic xws li ethanol thiab acetone tuaj yeem siv los faib HPMC ua ntej, thiab tom qab ntawd dej tuaj yeem ntxiv los pab HPMC yaj sai dua. Txoj kev no feem ntau siv rau hauv kev tsim cov khoom siv kuab tshuaj, xws li cov tshuaj pleev xim thiab cov xim pleev.
Txoj kev sib tov qhuav
Txoj kev sib tov qhuav yog qhov tsim nyog rau kev tsim khoom lag luam loj. HPMC feem ntau yog sib tov ua ntej qhuav nrog lwm cov khoom siv hmoov (xws li cement, gypsum, thiab lwm yam), thiab tom qab ntawd dej ntxiv rau hauv kev sib tov thaum siv. Txoj kev no ua kom yooj yim rau cov kauj ruam ua haujlwm thiab zam qhov teeb meem agglomeration thaum HPMC yaj ib leeg, tab sis yuav tsum tau do txaus tom qab ntxiv dej kom ntseeg tau tias HPMC tuaj yeem yaj sib npaug thiab ua lub luag haujlwm thickening.
3. Cov yam ntxwv uas cuam tshuam rau kev yaj HPMC
Kub: Qhov solubility ntawm HPMC yog rhiab heev rau qhov kub thiab txias. Qhov kub qis yog qhov ua rau nws tawg thiab yaj hauv dej, thaum qhov kub siab yooj yim ua rau HPMC tsim cov colloids, cuam tshuam nws cov kev yaj tag nrho. Yog li ntawd, nws feem ntau pom zoo kom siv dej txias lossis tswj qhov kub ntawm dej hauv qab 40 ° C thaum yaj HPMC.
Kev sib xyaw ceev: Kev sib xyaw kom zoo tuaj yeem tiv thaiv HPMC agglomeration, yog li ua kom nrawm dua qhov kev yaj. Txawm li cas los xij, kev sib xyaw ceev dhau tuaj yeem ua rau muaj ntau lub npuas thiab cuam tshuam rau qhov sib xws ntawm cov tshuaj. Yog li ntawd, thaum ua haujlwm tiag tiag, yuav tsum xaiv qhov ceev thiab cov khoom siv sib xyaw kom haum.
Dej zoo: Cov khoom tsis huv, qhov nyuaj, tus nqi pH, thiab lwm yam hauv dej yuav cuam tshuam rau qhov solubility ntawm HPMC. Tshwj xeeb, cov calcium thiab magnesium ions hauv dej tawv yuav cuam tshuam nrog HPMC thiab cuam tshuam rau nws qhov solubility. Yog li ntawd, kev siv dej ntshiab lossis dej mos pab txhim kho qhov ua tau zoo ntawm HPMC.
Tus qauv HPMC thiab qhov hnyav molecular: Cov qauv sib txawv ntawm HPMC sib txawv hauv qhov ceev ntawm kev yaj, viscosity thiab qhov kub ntawm kev yaj. HPMC nrog qhov hnyav molecular siab yaj qeeb qeeb, muaj viscosity siab ntawm cov tshuaj, thiab siv sijhawm ntev dua kom yaj tag. Kev xaiv tus qauv HPMC zoo tuaj yeem txhim kho kev ua haujlwm ntawm kev yaj thiab ua tau raws li cov kev xav tau ntawm kev siv sib txawv.
4. Cov teeb meem thiab kev daws teeb meem hauv kev yaj HPMC
Teeb meem sib sau ua ke: Thaum HPMC yaj hauv dej, kev sib sau ua ke yuav tsim tau yog tias cov hmoov tsis sib npaug. Txhawm rau kom tsis txhob muaj teeb meem no, HPMC yuav tsum tau ntxiv maj mam thaum lub sijhawm yaj thiab tswj hwm ntawm qhov ceev sib xyaw kom haum, thaum zam kev ntxiv hmoov HPMC ntawm qhov kub siab.
Kev daws teeb meem tsis sib xws: Yog tias qhov kev sib xyaw tsis txaus lossis lub sijhawm sawv tsis txaus, HPMC yuav tsis yaj tag, ua rau muaj kev daws teeb meem tsis sib xws. Lub sijhawm no, lub sijhawm sib xyaw yuav tsum tau ntev dua lossis lub sijhawm sawv yuav tsum tau nce ntxiv kom ntseeg tau tias yaj tag.
Teeb meem npuas: Kev do sai dhau lossis cov khoom tsis huv hauv dej yuav ua rau muaj ntau lub npuas, cuam tshuam rau qhov zoo ntawm cov tshuaj. Vim li no, nws raug pom zoo kom tswj qhov ceev ntawm kev do thaum yaj HPMC kom tsis txhob muaj npuas ntau dhau, thiab ntxiv cov tshuaj defoamer yog tias tsim nyog.
Kev yaj ntawm HPMC yog qhov txuas tseem ceeb hauv nws daim ntawv thov. Kev paub txog txoj kev yaj kom raug pab txhim kho cov khoom zoo thiab kev ua haujlwm zoo. Raws li ntau hom HPMC thiab cov kev xav tau ntawm daim ntawv thov, kev faib dej txias, kev yaj ua ntej dej kub, kev faib cov kuab tshuaj organic lossis kev sib tov qhuav tuaj yeem xaiv tau. Tib lub sijhawm, yuav tsum tau them sai sai rau cov yam ntxwv tswj xws li kub, kev sib xyaw ceev thiab dej zoo thaum lub sijhawm yaj kom tsis txhob muaj teeb meem xws li kev sib sau ua ke, npuas thiab kev yaj tsis tiav. Los ntawm kev ua kom zoo dua cov xwm txheej yaj, nws tuaj yeem ua kom ntseeg tau tias HPMC tuaj yeem muab kev ua si tag nrho rau nws cov khoom tuab thiab cov yeeb yaj kiab, muab cov kev daws teeb meem zoo rau ntau yam kev lag luam thiab kev siv txhua hnub.
Lub sijhawm tshaj tawm: Cuaj hlis-30-2024