1. Txheej txheem cej luam ntawm HPMC
Hydroxypropyl methylcellulose (HPMC luv luv) yog cov khoom siv polymer ntuj uas siv ntau, siv dav hauv kev tsim kho, tshuaj pleev xim, tshuaj, khoom noj thiab lwm yam teb. HPMC tau los ntawm kev hloov kho tshuaj ntawm cov cellulose ntuj, muaj kev yaj dej thiab biocompatibility, thiab tsis yaj hauv cov kuab tshuaj organic. Vim nws cov dej yaj zoo heev, kev nplaum, kev tuab, kev ncua thiab lwm yam khoom, HPMC tau siv dav hauv kev lag luam kev tsim kho, tshwj xeeb tshaj yog hauv kev siv hmoov putty.
2. Lub luag haujlwm ntawm HPMC hauv cov hmoov putty
Hmoov putty yog cov khoom siv hauv tsev siv rau kev kho phab ntsa, thiab nws cov khoom tseem ceeb yog cov khoom sau thiab cov khoom khi. HPMC, ua tus neeg sawv cev thickener thiab dej-tuav, tuaj yeem txhim kho kev ua tau zoo ntawm hmoov putty, tshwj xeeb suav nrog cov hauv qab no:
Cov nyhuv ua kom tuab: HPMC tsim cov tshuaj colloidal tom qab yaj hauv dej, uas muaj cov nyhuv tuab heev, tuaj yeem txhim kho cov khoom rheological ntawm cov hmoov putty, ua rau nws muaj viscosity tsim nyog, tsis txhob nyias dhau thaum thov, thiab txhim kho kev nplij siab ntawm kev ua haujlwm.
Txhim kho kev ua tau zoo ntawm kev tsim kho: HPMC qhov ua kom tuab tsis yog tsuas yog ua rau cov hmoov putty tsis tshua muaj feem yuav sag lossis ntws thaum lub sijhawm thov, tab sis kuj txhim kho qhov nplaum ntawm cov hmoov putty, ua rau nws yooj yim dua rau kev thov rau ntawm phab ntsa, yog li txhim kho kev ua haujlwm ntawm kev tsim kho.
Txhim kho kev khaws dej: HPMC tuaj yeem khaws dej hauv cov hmoov putty thiab qeeb qeeb qhov dej evaporation. Qhov no tuaj yeem tiv thaiv qhov chaw ntawm cov hmoov putty kom tsis txhob qhuav sai dhau, xyuas kom meej tias nws ua haujlwm tau thaum lub sijhawm tsim kho, thiab tiv thaiv kev tawg thiab poob.
Txhim kho qhov kov thiab qhov du ntawm qhov chaw: HPMC tsis yog tsuas yog txhim kho qhov ductility ntawm putty hmoov, tab sis kuj txhim kho nws qhov tiaj tus ntawm qhov chaw, ua rau cov txheej putty du, uas yog qhov zoo rau kev ua haujlwm pleev xim tom qab. Thaum lub sijhawm tsim kho, HPMC tuaj yeem muab qhov du zoo dua thiab txo qhov tshwm sim ntawm qhov tsis xws luag thiab npuas.
Txhim kho kev ruaj khov ntawm kev tsim kho: Kev ntxiv HPMC tuaj yeem txhim kho qhov tiv thaiv nag lossis daus ntawm cov hmoov putty, tiv thaiv kev tso cov khoom me me hauv nws, thiab xyuas kom meej tias qhov zoo thiab kev ua tau zoo ntawm cov hmoov putty yuav tsis hloov pauv ntau thaum lub sijhawm khaws cia ntev.
Txhim kho qhov tsis kam tawg: Los ntawm kev khaws dej thiab cov nyhuv tuab ntawm HPMC, qhov tsis kam tawg ntawm cov hmoov putty tuaj yeem txhim kho, cov kab nrib pleb ntawm phab ntsa tuaj yeem zam tau, thiab lub neej kev pabcuam tuaj yeem ntev dua.
3. Qhov viscosity tsim nyog ntawm HPMC
Qhov cuam tshuam ntawm HPMC hauv cov hmoov putty muaj feem cuam tshuam nrog nws cov viscosity. Kev xaiv ntawm viscosity yuav tsum tau txiav txim siab raws li qhov xav tau tshwj xeeb ntawm cov hmoov putty thiab qhov chaw tsim kho. Feem ntau hais lus, qhov viscosity ntawm HPMC yog txij li pua pua txog kaum txhiab millipoise (mPa · s), ntawm cov viscosities sib txawv yog qhov tsim nyog rau ntau hom hmoov putty thiab kev tsim kho.
HPMC uas tsis muaj viscosity ntau (kwv yees li 1000-3000 mPa·s): haum rau cov hmoov putty uas tsis hnyav lossis cov putty hauv paus, feem ntau yog siv rau hauv cov xwm txheej uas xav tau kev ua kua ntau dua. HPMC uas tsis muaj viscosity ntau tuaj yeem muab kev ua haujlwm zoo dua, ua rau cov hmoov putty yooj yim rau kev ua haujlwm, tab sis kev khaws dej thiab kev tiv thaiv tawg tsis muaj zog.
Qhov nruab nrab viscosity HPMC (kwv yees li 3000-8000 mPa · s): haum rau feem ntau cov mis hmoov putty, uas tuaj yeem muab cov dej zoo thiab tiv thaiv nag thaum tswj cov kua dej zoo. HPMC ntawm qhov viscosity no tsis tsuas yog ua tau raws li qhov xav tau ntawm cov txheej txheem thaum lub sijhawm tsim kho, tab sis kuj tseem tiv thaiv cov teeb meem xws li tawg thiab poob tawm.
HPMC viscosity siab (kwv yees li 8000-20000 mPa · s): haum rau cov txheej tuab ntawm cov hmoov putty lossis cov xwm txheej uas xav tau cov nyhuv tuab. HPMC viscosity siab tuaj yeem muab kev ua haujlwm zoo dua thiab ruaj khov ntawm cov txheej tuab, thiab haum rau cov ntawv thov txheej uas xav tau kev sib txhuam zoo thiab du, tab sis nws yuav tsum tau sau tseg tias viscosity siab dhau yuav ua rau cov hmoov putty viscous dhau thiab cuam tshuam rau kev ua haujlwm ntawm kev tsim kho.
Hauv kev siv ua haujlwm, yuav tsum xaiv qhov viscosity HPMC raws li qhov xwm txheej siv thiab txoj kev tsim cov hmoov putty. Piv txwv li, thaum lub ntsej muag ntawm phab ntsa tsis zoo lossis xav tau ntau yam kev tsim kho, HPMC viscosity siab dua tuaj yeem xaiv los txhim kho qhov kev nplaum thiab kev tawg ntawm cov txheej; thaum lub sijhawm uas xav tau kev ua kua ntau dua thiab kev tsim kho sai dua, HPMC viscosity qis mus rau nruab nrab tuaj yeem xaiv.
Hydroxypropyl methylcelluloseyog ib qho tseem ceeb ntawm kev tsim kho uas tuaj yeem txhim kho kev ua tau zoo ntawm kev tsim kho, kev khaws dej, kev nplaum thiab kev tawg ntawm cov hmoov putty. Kev xaiv qhov viscosity HPMC yog qhov tseem ceeb rau kev siv cov hmoov putty. Cov viscosities sib txawv tuaj yeem hloov kho raws li hom hmoov putty, ib puag ncig kev tsim kho, thiab cov kev xav tau kev ua tau zoo. Hauv kev tsim khoom tiag tiag thiab kev tsim kho, kev tswj hwm qhov viscosity ntawm HPMC tuaj yeem ua tiav cov txiaj ntsig zoo tshaj plaws ntawm kev tsim kho thiab kev ua tau zoo mus sij hawm ntev. Yog li ntawd, raws li cov kev xav tau kev tsim kho sib txawv, kev xaiv thiab kho qhov viscosity ntawm HPMC yog ib kauj ruam tseem ceeb kom ntseeg tau tias muaj kev ua tau zoo thiab zoo ntawm cov hmoov putty.
Lub sijhawm tshaj tawm: Lub Peb Hlis-25-2025