Yuav ua li cas yaj HPMC kom raug

Hydroxypropyl Methylcellulose (HPMC)yog ib qho cellulose ether uas tsis yog ionic siv dav hauv kev lag luam xws li kev tsim kho, tshuaj, khoom noj, tshuaj pleev ib ce, thiab kev pleev xim. Nws ua haujlwm ua ib qho thickener, binder, film former, emulsifier, stabilizer, thiab tus neeg sawv cev khaws dej. Kev yaj kom zoo ntawm HPMC yog qhov tseem ceeb kom ntseeg tau tias nws ua tiav nws cov haujlwm zoo tshaj plaws hauv daim ntawv thov zaum kawg. Vim nws cov khoom thermogelation - ua viscous ntau dua lossis tsim cov gel ntawm qhov kub siab dua - yuav tsum tau ua tib zoo saib xyuas cov txheej txheem yaj.

1. Nkag Siab Txog Cov Khoom ntawm HPMC

Yuav kom yaj HPMC kom raug, nws yog ib qho tseem ceeb kom nkag siab txog nws cov khoom yooj yim:

Kev ua kom rov qab tau qhov kub thiab txias: HPMC yaj hauv dej txias tab sis tsis yaj hauv dej kub. Thaum kub siab (saum toj no 60–80 ° C nyob ntawm hom), nws feem ntau o thiab tsim cov gels lossis pob.

Xwm txheej tsis yog ionic: Nws tsis cuam tshuam nrog cov ntsev lossis cov tshuaj ionic, ua rau nws ruaj khov hauv ntau yam qauv.

Hydrophilic thiab zaj duab xis-tsim: Nws nyiam dej thiab tsim cov colloid tiv thaiv nyob ib puag ncig cov khoom khov.

Cov khoom no qhia tias HPMC yuav tsum tau ua haujlwm rau hauv ib txoj kev tshwj xeeb kom tsis txhob o lossis clumping tsis raug.

2. Cov Ntsiab Cai Dav Dav ntawm Kev Yaj HPMC

2.1. Tsis txhob muaj pob

HPMC yaj zoo tshaj plaws thaum nws cov khoom me me tau tawg zoo hauv dej ua ntej ua kom noo. Yog tias ntxiv hmoov ncaj qha rau hauv dej txias yam tsis muaj kev tawg, nws feem ntau yuav sib sau ua ke thiab tsim cov pob gel uas tsis tau yaj.

2.2. Kev rhiab heev ntawm qhov kub thiab txias

Vim tias HPMC tsim cov gel hauv dej kub tab sis yaj hauv txias, qhov kev yaj feem ntau siv ob txoj kev uas muaj kev sib xyaw ua ke nrog dej kub ua raws li kev ua kom dej txias.

3. Cov Txheej Txheem Siv Los Ua Kom Yaj

Muaj ntau txoj hauv kev zoo los yaj HPMC nyob ntawm daim ntawv thov thiab cov khoom siv muaj:

Txoj Kev 1: Kev Sib Nraus Dej Kub, Kev Sib Nraus Dej Txias (Txoj Kev Ob Theem)

Qhov no yog txoj kev siv ntau tshaj plaws thiab txhim khu kev qha.

Cov Kauj Ruam:

Ua kom dej kub txog 70-90 ° C.

Maj mam yaj HPMC rau hauv dej kub thiab sib npaug zos thaum do. Thaum xub thawj HPMC yuav ntab thiab tom qab ntawd yuav yaj mus ua cov slurry dawb uas raug tshem tawm. Nws yuav tsis yaj rau theem no.

Txuas ntxiv do rau 5-10 feeb, kom ntseeg tau tias sib xyaw kom sib npaug.

Ntxiv dej txias (0–20°C) los yog cia cov khoom sib tov txias li qub kom qis dua 40°C.

Txuas ntxiv do. Thaum qhov kub poob qis, HPMC pib hydrate thiab yaj, tsim cov tshuaj meej lossis me ntsis opalescent.

Txoj kev no tiv thaiv kev sib sau ua ke thiab ua kom muaj dej sib npaug.

Txoj Kev 2: Sib Tov Qhuav Nrog Lwm Cov Hmoov

Siv thaum HPMC yog ib feem ntawm cov mis sib tov qhuav (piv txwv li, cov nplaum pobzeb lossis cov cement-based mortars).

Cov Kauj Ruam:

Ua ntej sib tov HPMC hmoov kom huv si nrog lwm cov khoom xyaw qhuav (piv txwv li, cement, xuab zeb, lossis cov khoom sau).

Thaum ntxiv dej rau ntawm qhov chaw thaum lub sijhawm thov, HPMC tau sib kis thoob plaws, thiab zam kev sib sau ua ke.

Sib tov kom huv si kom ntseeg tau tias muaj dej thiab yaj thaum cov khoom qhuav ntub.

Txoj kev no zoo tagnrho rau cov ntaub ntawv siv hauv kev tsim kho.

Txoj Kev 3: Kev Sib Xyaws Ua Ntej Cov kuab tshuaj (Cawv lossis Glycol Carriers)

Siv rau hauv cov chaw teeb tsa kev lag luam tshwj xeeb.

Cov Kauj Ruam:

Sib tov HPMC hmoov nrog cov kuab tshuaj xws li ethanol lossis propylene glycol.

Ntxiv cov sib tov no rau hauv dej.

Do tas li. HPMC tawg zoo thiab yaj thaum cov kuab tshuaj diffuses.

Txoj kev no txo ​​qhov kev pheej hmoo ntawm kev sib sau ua ke, tshwj xeeb tshaj yog nyob rau hauv cov kab ke uas muaj kev cuam tshuam tsawg.

4. Cov Lus Qhia Siv Tau Zoo Rau Kev Yaj Kom Raug

Siv lub tshuab sib tov lossis lub tshuab sib tov uas muaj zog heev: Kev sib tov ua kom cov khoom sib xyaw sib npaug thiab txo lub sijhawm yaj.

Maj mam ntxiv: Tsis txhob muab HPMC pov rau hauv dej ib zaug - txau kom sib npaug.

Siv dej txias los yog dej kub hauv chav ua ntej, los yog siv txoj kev kub-txias raws li tau piav qhia saum toj no.

Ua ntej ntub nrog cov kuab tshuaj hauv cov formulations qhov twg qhov no tsim nyog.

Lub sijhawm tsau dej: Qee hom HPMC xav tau 30-60 feeb kom hydrate tag nrho.

5. Cov Lus Qhia Txog Khoom Siv

Nyob ntawm koj qhov ntsuas thiab daim ntawv thov:

Kev sib tov me me hauv chav kuaj: Siv cov khoom sib xyaw hlau nplaum lossis cov khoom sib tov saum toj.

Kev lag luam hauv kev lag luam: Siv cov ribbon mixers, high-speed dispersers, lossis emulsifiers.

Cov txheej txheem txuas ntxiv mus: Cov khoom sib tov ua ke hauv kab siab lossis cov khoom sib tov dav hlau ua haujlwm tau zoo.

7. Kev Xav Txog Tshwj Xeeb Rau Daim Ntawv Thov

Cov Khoom Siv Tsim Kho

Kev faib ua ntej feem ntau yog ua los ntawm kev sib xyaw qhuav nrog cov cement lossis gypsum.

Thaum ntxiv dej, HPMC hydrates thiab muab kev ua haujlwm tau zoo, khaws dej, thiab sib xws.

Cov Tshuaj

Hauv cov ntsiav tshuaj lossis tshuaj ntsiav, HPMC feem ntau siv ua tus khi lossis tus neeg sawv cev tswj hwm.

Siv HPMC qib tshuaj thiab ua raws li cov txheej txheem yaj uas tau lees paub.

Khoom noj thiab tshuaj pleev ib ce

Feem ntau yaj siv dej sov hauv qab qhov kub gelation.

Kev sib xyaw ua ke siab pab tiv thaiv kom tsis txhob pom cov pob hauv cov gels thiab emulsions.

8. Cov Lus Qhia Txog Kev Khaws Cia thiab Kev Siv Khoom

Khaws HPMC kom qhuav thiab kaw: Cov dej noo tuaj yeem ua rau muaj dej noo thiab sib sau ua ke thaum khaws cia.

Tsis txhob kub dhau thaum lub sijhawm khaws cia kom cov khoom ruaj khov.

Siv cov khoom siv tiv thaiv tus kheej (PPE) kom tsim nyog thaum kov cov khoom ntau ntau kom tsis txhob ua pa lossis khaus tawv nqaij.

Kev yaj HPMC kom raugyog qhov tseem ceeb rau kev siv nws cov khoom siv tag nrho hauv ntau yam qauv. Qhov tseem ceeb yog kev nkag siab txog nws tus cwj pwm thermal thiab xyuas kom meej tias muaj kev sib kis zoo ua ntej hydration. Txoj kev siv dej kub / txias ob theem yog txoj hauv kev siv dav tshaj plaws los ua kom tiav tag nrho thiab tsis muaj pob. Los ntawm kev tswj qhov kub, kev sib xyaw ua ke, thiab qhov ceev ntxiv, cov neeg siv tuaj yeem ua kom muaj kev daws teeb meem HPMC zoo rau lawv cov kev xav tau tshwj xeeb hauv kev lag luam lossis chaw kuaj mob.