HPMC (Hydroxypropyl Methylcellulose)yog ib qho polymer non-ionic semi-synthetic uas siv dav hauv tshuaj, khoom noj, kev tsim kho, kev pleev xim thiab lwm yam lag luam. Txog seb HPMC puas tuaj yeem yaj hauv dej kub, nws cov yam ntxwv solubility thiab qhov cuam tshuam ntawm qhov kub rau nws tus cwj pwm yaj yuav tsum tau xav txog.
Txheej txheem cej luam ntawm HPMC solubility
HPMC muaj cov dej solubility zoo, tab sis nws cov cwj pwm yaj yog ze rau qhov kub ntawm dej. Feem ntau, HPMC tuaj yeem yooj yim tawg thiab yaj hauv dej txias, tab sis nws qhia txog cov yam ntxwv sib txawv hauv dej kub. Qhov solubility ntawm HPMC hauv dej txias feem ntau cuam tshuam los ntawm nws cov qauv molecular thiab hom substituent. Thaum HPMC los rau hauv kev sib cuag nrog dej, cov pab pawg hydrophilic (xws li hydroxyl thiab hydroxypropyl) hauv nws cov molecules yuav tsim cov hydrogen bonds nrog cov dej molecules, ua rau nws maj mam o thiab yaj. Txawm li cas los xij, cov yam ntxwv solubility ntawm HPMC yog txawv hauv dej ntawm qhov kub sib txawv.
Kev yaj ntawm HPMC hauv dej kub
Qhov solubility ntawm HPMC hauv dej kub nyob ntawm qhov kub thiab txias:
Qhov kub qis (0-40 ° C): HPMC tuaj yeem nqus dej maj mam thiab o, thiab thaum kawg tsim cov kua pob tshab lossis pob tshab. Qhov nrawm ntawm kev yaj qeeb qeeb ntawm qhov kub qis dua, tab sis gelation tsis tshwm sim.
Kub nruab nrab (40-60 ° C): HPMC swells nyob rau hauv qhov kub no, tab sis tsis yaj tag. Hloov chaw, nws yooj yim tsim cov agglomerates tsis sib xws lossis cov suspensions, cuam tshuam rau qhov sib xws ntawm cov tshuaj.
Kub siab (saum toj no 60 ° C): HPMC yuav dhau los ua kev sib cais theem ntawm qhov kub siab dua, qhia tau tias yog gelation lossis nag lossis daus, ua rau nws nyuaj rau yaj. Feem ntau hais lus, thaum qhov kub ntawm dej tshaj 60-70 ° C, qhov kev txav thermal ntawm HPMC molecular saw hlau nce ntxiv, thiab nws cov solubility txo qis, thiab nws thaum kawg yuav tsim cov gel lossis nag lossis daus.
Cov khoom ntawm Thermogel ntawm HPMC
HPMC muaj cov khoom thermogel ib txwm muaj, uas yog, nws tsim cov gel ntawm qhov kub siab dua thiab tuaj yeem yaj dua ntawm qhov kub qis. Cov khoom no tseem ceeb heev rau ntau daim ntawv thov, xws li:
Kev lag luam kev tsim kho: HPMC yog siv los ua cov khoom siv ua kom tuab rau cov cement mortar. Nws tuaj yeem tswj tau cov dej noo zoo thaum lub sijhawm tsim kho thiab ua kom pom cov gelation hauv qhov chaw kub siab kom txo cov dej poob.
Kev npaj tshuaj: Thaum siv ua cov khoom siv txheej hauv cov ntsiav tshuaj, nws cov khoom siv thermal gelation yuav tsum tau txiav txim siab kom ntseeg tau tias muaj kev yaj zoo.
Kev lag luam zaub mov: HPMC yog siv los ua cov khoom ua kom tuab thiab emulsifier hauv qee cov zaub mov, thiab nws cov thermal gelation pab kom cov zaub mov ruaj khov.
Yuav ua li cas yaj HPMC kom raug?
Yuav kom tsis txhob muaj HPMC los ntawm kev tsim cov gel hauv dej kub thiab tsis yaj kom sib npaug, cov hau kev hauv qab no feem ntau siv:
Txoj kev faib dej txias:
Ua ntej, sib npaug zos faib HPMC hauv dej txias lossis dej kub hauv chav tsev kom ntub tag nrho thiab o.
Maj mam nce qhov kub thaum lub sijhawm do kom yaj HPMC ntxiv.
Tom qab nws yaj tag lawm, qhov kub tuaj yeem nce ntxiv kom tsim nyog kom nrawm dua qhov kev tsim cov tshuaj.
Txoj kev txias dej kub:
Ua ntej, siv dej kub (kwv yees li 80-90 ° C) kom sai sai tawg HPMC kom cov txheej tiv thaiv gel tsis yaj tau tsim rau ntawm nws qhov chaw kom tiv thaiv kev tsim cov pob nplaum tam sim ntawd.
Tom qab txias mus rau chav tsev kub lossis ntxiv dej txias, HPMC maj mam yaj los ua ib qho kev daws teeb meem sib xws.
Txoj kev sib tov qhuav:
Sib tov HPMC nrog lwm cov tshuaj yaj (xws li qab zib, hmoov txhuv nplej siab, mannitol, thiab lwm yam) thiab tom qab ntawd ntxiv dej kom txo qhov sib sau ua ke thiab txhawb kev yaj sib npaug.
HPMCtsis tuaj yeem yaj ncaj qha rau hauv dej kub. Nws yooj yim los ua gel lossis precipitate ntawm qhov kub siab, uas txo nws cov solubility. Txoj kev yaj zoo tshaj plaws yog disperse hauv dej txias ua ntej lossis pre-disperse nrog dej kub thiab tom qab ntawd txias kom tau txais cov tshuaj sib xws thiab ruaj khov. Hauv kev siv ua haujlwm, xaiv txoj kev yaj tsim nyog raws li qhov xav tau kom ntseeg tau tias HPMC ua haujlwm zoo tshaj plaws.
Lub sijhawm tshaj tawm: Lub Peb Hlis-25-2025