Hydroxypropyl methyl cellulose HPMC, ʻike ʻia ʻo hydroxypromellose, he keʻokeʻo keʻokeʻo cellulose ether pauka a i ʻole granule i loaʻa i ka wai anuanu a me ka wai wela e like me ka methyl cellulose. ʻO ka hui hydroxypropyl a me ka pūʻulu methyl he paʻa etera a me ke apo glucose anhydrous o cellulose i hui pū ʻia, he ʻano o ka non-ionic cellulose i hui ʻia eter. He semi-synthetic, inactive, viscoelastic polymer i hoʻohana mau ʻia ma ke ʻano he lubricant i ka ophthalmology, a i ʻole he excipient a excipient paha i nā lāʻau lapaʻau waha.
1. Ke kaʻina hana
Kraft pulp me ka αcellulose maʻiʻo o 97%, intrinsic viscosity o 720mL / g a me ka awelika fiber lōʻihi o 2.6mm ua pulu i loko o 49% NaOH solution ma 40 ℃ no 50 kekona. A laila ua hoʻokuʻu ʻia ka pulp e wehe i ka hopena 49% NaOH e loaʻa ai ka cellulose alkali. ʻO ka lākiō kaumaha o (49% NaOH aqueous solution) i (mea paʻa o ka pulp) i ka pae impregnation he 200. ʻO ka lākiō kaumaha o NaOH i ka cellulose alkali a paʻa i ka pulp he 1.49. Hoʻokomo ʻia ka cellulose alkali i loaʻa (20kg) i loko o kahi reactor kaomi jacked me ka hoʻoulu ʻana i loko, a laila holoi ʻia a hoʻomaʻemaʻe ʻia me ka nitrogen e hoʻoneʻe pono i ka oxygen mai ka reactor. A laila, mālama ʻia ka mahana o ka reactor ma 60 ℃ i ka wā i hoʻokō ʻia ai ka hoʻoulu ʻana i loko.
A laila ua hoʻohui ʻia ka 2.4kg dME a ua mālama ʻia ka mahana o ka reactor i 60 ℃. Ma hope o ka hoʻohui ʻana o ka dimethyl ether, ua hoʻohui ʻia ka methylene chloride e hana i ka ratio molar o ka methylene chloride i NaOH i ka cellulose alkaline 1.3, ua hoʻohui ʻia ka propylene oxide e hana i ka ratio kaumaha o ka propylene oxide i paʻa i ka pulp 1.97, a ua hoʻomalu ʻia ka mahana o ka reactor mai 60 ℃ a 80 ℃. Ma hope o ka hoʻohui ʻana i ka chloromethane a me ka propylene oxide, ua mālama ʻia ka mahana o ka reactor mai 80 ℃ a 90 ℃. Eia kekahi, ua mau ka hopena no 20 mau minuke ma 90 ℃.
Hoʻokahe ʻia ke kinoea mai ka reactor a hoʻoneʻe ʻia ka crude hydroxypropyl methyl cellulose mai ka reactor. He 62 ℃ ka mahana o ka hydroxypropyl methyl cellulose. E ana i ka huina 50% ka nui o ka nui ma ka puunaue kumulative ma muli o ke kaumaha ma muli o ka ratio o ka hydroxypropyl methyl cellulose crude ma o na puka o na sieving elima, he okoa ko kela mea keia mea.
ʻO ka hopena, ʻo 6.2mm ka nui o ka nui o nā ʻāpana koʻikoʻi. Ua hoʻokomo ʻia ka crude hydroxypropyl methyl cellulose i loko o kahi kneader biaxial mau loa (KRC kneader S1, L / D = 10.2, ka nui o loko 0.12 L, ka wikiwiki o ka rotation 150rpm) ma ka wikiwiki o 10kg / hr, a ua loaʻa ka decomposed crude hydroxypropyl methyl cellulose. ʻO ka hopena o nā ana like me ka hoʻohana ʻana i nā pale 5 me nā ʻano wehe like ʻole, ʻo 1.4mm ka awelika o ka nui o nā ʻāpana. Hoʻohui i 80 ℃ wai wela i ka decomposed crude hydroxypropyl methyl cellulose i loko o ka pahu me ka mālama ʻana i ka mahana o ka lole. ka nui o ka ratio kaumaha o ka decomposed crude hydroxypropyl methyl cellulose i ka huina o ka slurry he 0.1, a ua loaa ka slurry. Hoʻoulu ʻia ka slurry ma kahi mahana mau o 80 ℃ no 60 mau minuke.
A laila, hāʻawi ʻia ka slurry i ka wikiwiki o ka huli ʻana o 0.5 RPM a me ka kānana kaomi rotary pre-heated (BHS Sonthofen huahana). ʻO ka mahana o ka grout he 93 ℃. E hoʻohana i ka paila no ka hoʻolako ʻana i ka slurry, ʻo ke kaomi hoʻokuʻu ʻana he 0.2mpa. ʻO ka nui o ka wehe ʻana o ka kānana puʻe rotary he 80μm, a ʻo ka wahi kānana he 0.12m2. Hoʻopili ʻia ka slurry i hāʻawi ʻia i ka kānana kaomi rotary ma o ka kānana a hoʻololi ʻia i keke kānana. Hāʻawi ʻia ka keke kānana hopena me ka mahu 0.3mpa a me ka wai wela 95 ℃ me ka ratio kaumaha o 10.0 i ka mea paʻa o ka HYDROXYpropyl methyl cellulose i holoi ʻia, a laila kānana ʻia ma o kahi kānana.
Hāʻawi ʻia ka wai wela ma o ka pauma ma kahi kaomi hoʻokuʻu o 0.2mpa. Ma hope o ka hoʻolako ʻia ʻana o ka wai wela, hāʻawi ʻia ka mahu 0.3mpa. A laila, ma hope o ka holoi ʻana, wehe ʻia nā huahana mai ka ʻili kānana e kahi ʻōpala a hoʻokuʻu ʻia i waho o ka mīkini holoi. Hoʻomau ʻia nā ʻanuʻu mai ka hāʻawi ʻana i ka slurry i ka hoʻokuʻu ʻana i nā huahana holoi ʻia. E like me ke ana ʻana me ka hoʻohana ʻana i kahi hygrometer maloʻo wela, ʻo 52.8% ka nui o ka wai o ka huahana holoi ʻia i hoʻokuʻu ʻia. ʻO nā huahana i holoi ʻia i hoʻokuʻu ʻia mai ka kānana kaomi rotary ua hoʻomaloʻo ʻia e kahi mea maloʻo ea ma 80 ℃, a ʻoki ʻia i ka wili lanakila e loaʻa ai ka hydroxypropyl methyl cellulose.
2.Ka noi
HPMCHoʻohana ʻia ka huahana e like me thickener, dispersant, binder, emulsifier a me stabilizer i ka ʻoihana textile. Hoʻohana nui ʻia i ka resin synthetic, petrochemical, ceramic, pepa, ʻili, lāʻau lapaʻau, meaʻai, mea hoʻonaninani a me nā ʻoihana ʻē aʻe.
Ka manawa hoʻouna: Apr-26-2024