Cellulose, ib qho ntawm cov organic tebchaw tshaj plaws nyob rau hauv lub ntiaj teb, pom kev siv dav hauv ntau qhov kev lag luam vim nws cov khoom tshwj xeeb. Hauv kev lag luam kws kho mob, cellulose thiab nws cov derivatives ua lub luag haujlwm tseem ceeb hauv kev xa tshuaj, tshuaj ntsiav tshuaj, kev hnav khaub ncaws, thiab lwm yam.
1. Binder hauv Tablet Formulations:
Cellulose derivatives xws li microcrystalline cellulose (MCC) thiab hmoov cellulose ua haujlwm zoo hauv cov ntsiav tshuaj formulations. Lawv txhim kho kev sib koom ua ke thiab kev siv lub zog ntawm cov ntsiav tshuaj, kom ntseeg tau tias cov tshuaj sib xyaw ua ke thiab kev tso tawm zoo ib yam.
2. Disintegrant:
Cellulose derivatives zoo li croscarmellose sodium thiab sodium carboxymethyl cellulose (NaCMC) ua raws li disintegrants hauv cov ntsiav tshuaj, ua kom yooj yim tawg sai ntawm cov ntsiav tshuaj matrix thaum sib cuag nrog cov kua dej. Cov cuab yeej no txhim kho cov tshuaj yaj yeeb thiab bioavailability.
3. Tswj Kev Xa Tshuaj:
Cellulose derivatives yog cov khoom tseem ceeb hauv kev tswj-tso formulations. Los ntawm kev hloov kho cov qauv tshuaj los yog qhov loj me ntawm cellulose, kev txhawb nqa, txuas ntxiv, lossis cov phiaj xwm tso tawm cov yeeb yaj kiab tuaj yeem ua tiav. Qhov no tso cai rau kev xa tshuaj zoo tshaj plaws, txo kev siv tshuaj ntau zaus, thiab txhim kho kev ua raws li tus neeg mob.
4. Txheej Khoom:
Cellulose derivatives xws li ethyl cellulose thiab hydroxypropyl methylcellulose (HPMC) feem ntau yog siv los ua zaj duab xis txheej rau cov ntsiav tshuaj thiab granules. Lawv muab kev tiv thaiv kev tiv thaiv, npog lub ntsej muag tsis zoo, tswj cov tshuaj tso tawm, thiab txhim kho kev ruaj ntseg.
5. Thickening thiab Stabilizing Agent:
Cellulose ethers zoo li HPMC thiab sodium carboxymethyl cellulose yog ua hauj lwm raws li thickening thiab stabilizing cov neeg ua hauj nyob rau hauv cov kua ntau npaum li cas xws li ncua kev kawm ntawv, emulsions, thiab syrups. Lawv txhim kho viscosity, tiv thaiv sedimentation, thiab xyuas kom meej cov tshuaj sib xws.
6. Excipient hauv Topical Formulations:
Hauv cov tshuaj pleev ib ce zoo li cream, tshuaj pleev, thiab gels, cellulose derivatives pab ua viscosity modifiers, emulsifiers, thiab stabilizers. Lawv muab cov khoom tsim nyog rheological, txhim khu kev sib kis, thiab txhawb nqa adhesion rau ntawm daim tawv nqaij los yog mucous daim nyias nyias.
7. Kev hnav khaub ncaws:
Cellulose-raws li cov ntaub ntawv, suav nrog oxidized cellulose thiab carboxymethyl cellulose, yog siv nyob rau hauv lub qhov txhab hnav vim lawv hemostatic, absorbent, thiab antimicrobial zog. Cov hnav khaub ncaws no txhawb kev kho qhov txhab, tiv thaiv kab mob, thiab ua kom lub qhov txhab ntub dej.
8. Scaffold hauv Tissue Engineering:
Cellulose scaffolds muab biocompatible thiab biodegradable matrix rau cov ntaub so ntswg engineering daim ntaub ntawv. Los ntawm kev koom nrog cov neeg ua haujlwm bioactive lossis cov hlwb, cov cellulose-based scaffolds tuaj yeem pab txhawb kev tsim cov ntaub so ntswg thiab kho hauv ntau yam mob.
9. Capsule Formulation:
Cellulose derivatives xws li hypromellose thiab hydroxypropyl cellulose yog siv los ua cov khoom siv tshuaj ntsiav, muab lwm txoj hauv kev rau gelatin capsules. Cellulose-based capsules yog tsim rau ob qho tib si tam sim thiab hloov kho-tso formulations thiab nyiam rau cov neeg tsis noj nqaij los yog kev cai dab qhuas txwv kev noj haus.
10. Carrier nyob rau hauv Solid Dispersion Systems:
Cellulose nanoparticles tau txais kev saib xyuas raws li cov neeg nqa khoom rau cov tshuaj tsis zoo dej-soluble hauv cov khoom tawg. Lawv thaj chaw siab, porosity, thiab biocompatibility pab txhim kho cov tshuaj tawg thiab bioavailability.
11. Daim Ntawv Thov Kev Ua Phem Txhaum Cai:
Cellulose-raws li cov ntaub ntawv tuaj yeem muab tso rau hauv kev ntim tshuaj raws li kev tiv thaiv kev ua txhaum cai. Cim cellulose-raws li cim npe lossis cov ntawv cim nrog kev ruaj ntseg nta tuaj yeem pab txheeb xyuas cov khoom siv tshuaj thiab tiv thaiv cov neeg cuav.
12. Inhalation Drug Delivery:
Cellulose derivatives zoo li microcrystalline cellulose thiab lactose yog siv los ua cov khoom siv rau cov hmoov qhuav nqus dej. Cov neeg nqa khoom no ua kom muaj kev sib cais ntawm cov tshuaj thiab pab txhawb kev xa mus rau txoj kev ua pa.
cellulose thiab nws cov derivatives pab ua ntau yam excipients thiab cov ntaub ntawv nyob rau hauv kev lag luam kws tshuaj, pab rau txoj kev loj hlob ntawm kev nyab xeeb, zoo, thiab cov neeg mob-phooj ywg cov khoom siv tshuaj. Lawv cov khoom tshwj xeeb ua rau muaj ntau yam kev siv, los ntawm cov ntsiav tshuaj formulations mus rau kev kho mob thiab cov ntaub so ntswg engineering, ua cellulose ib tug indispensable tivthaiv nyob rau hauv niaj hnub kws tshuaj formulations thiab cov khoom siv kho mob.
Lub sij hawm xa tuaj: Plaub Hlis-18-2024