Nkag siab txog Hydroxypropyl Methyl Cellulose (HPMC)
Hydroxypropyl Methyl Cellulose (HPMC) yog cov khoom siv hluav taws xob ntau yam siv dav hauv ntau yam lag luam, suav nrog tshuaj, khoom noj, tshuaj pleev ib ce, thiab kev tsim kho. Nws cov khoom tshwj xeeb, xws li dej solubility, gelation thaum cua sov, thiab kev ua yeeb yaj kiab, ua rau nws muaj txiaj ntsig zoo hauv ntau cov qauv. Ib qho ntawm cov khoom tseem ceeb ntawm HPMC yog nws cov viscosity, uas cuam tshuam rau nws txoj haujlwm thiab kev siv.
Cov yam ntxwv cuam tshuam rau viscosity ntawm HPMC
Ntau yam cuam tshuam rau viscosity ntawm HPMC, suav nrog:
Molecular Luj: Cov qib molecular hnyav dua HPMC feem ntau pom muaj viscosity ntau dua.
Concentration: Lub viscosity nce nrog cov concentration ntawm HPMC hauv cov tshuaj.
Kub: viscosity txo nrog qhov kub thiab txias vim tias cov saw hlau polymer ua ntau dua.
pH: HPMC ruaj khov nyob thoob plaws pH ntau yam, tab sis huab cua pH siab tuaj yeem cuam tshuam viscosity.
Degree of Hloov (DS) thiab Molar Hloov (MS): Cov qib ntawm kev hloov pauv (cov naj npawb ntawm cov pab pawg hydroxyl hloov los ntawm methoxy lossis hydroxypropyl pawg) thiab molar hloov pauv (tus naj npawb ntawm hydroxypropyl pawg hauv ib chav tsev piam thaj) cuam tshuam rau solubility thiab viscosity ntawm HPMC
Tsim nyog viscosity rau ntau daim ntawv thov
Qhov tsim nyog viscosity ntawm HPMC nyob ntawm daim ntawv thov tshwj xeeb. Nov yog cov ncauj lus kom ntxaws txog yuav ua li cas viscosity yuav tsum sib txawv ntawm cov kev lag luam sib txawv:
1. Pharmaceuticals
Hauv kev lag luam tshuaj, HPMC yog siv los ua cov ntawv khi, zaj duab xis-yav dhau los, thiab tswj-tso tus neeg sawv cev hauv cov ntsiav tshuaj thiab tshuaj ntsiav.
Tablet Txheej: Tsawg mus rau nruab nrab viscosity HPMC (3-5% tov nrog 50-100 cps) yog tsim rau txheej zaj duab xis, muab cov txheej txheem du, tiv thaiv.
Tswj Kev Tso Tawm: High viscosity HPMC (1% tov nrog 1,500-100,000 cps) yog siv rau hauv cov ntsiav tshuaj matrix los tswj qhov tso tawm ntawm cov khoom muaj txiaj ntsig, ua kom muaj kev tso tawm raws sijhawm.
Binder hauv Granulation: Nruab nrab viscosity HPMC (2% tov nrog 400-4,000 cps) yog qhov zoo dua rau cov txheej txheem ntub dej granulation los ua granules nrog lub zog zoo txhua yam.
2. Kev lag luam zaub mov
Hauv kev lag luam zaub mov, HPMC yog siv los ua cov thickener, stabilizer, thiab emulsifier.
Thickening Agent: Tsawg mus rau nruab nrab viscosity HPMC (1-2% tov nrog 50-4,000 cps) yog siv los ua kua ntses, hnav khaub ncaws, thiab kua zaub.
Emulsifier thiab Stabilizer: Tsis tshua muaj viscosity HPMC (1% tov nrog 10-50 cps) yog tsim rau stabilizing emulsions thiab foams, muab cov kev xav zoo nkauj hauv cov khoom xws li ice cream thiab whipped toppings.
3. Tshuaj pleev ib ce thiab kho tus kheej
HPMC yog siv rau hauv cov tshuaj pleev ib ce rau nws cov thickening, film-forming, thiab moisturizing zog.
Lotions thiab Creams: Tsawg mus rau nruab nrab viscosity HPMC (1% tov nrog 50-4,000 cps) muab qhov xav tau sib xws thiab ruaj khov.
Cov Khoom Siv Kho Hniav: Nruab nrab viscosity HPMC (1% tov nrog 400-4,000 cps) yog siv rau hauv cov tshuaj zawv plaub hau thiab cov tshuaj kho kom zoo nkauj thiab kev ua haujlwm.
4. Kev tsim kho kev lag luam
Hauv kev tsim kho, HPMC yog ib qho tseem ceeb hauv cov khoom xws li cov nplaum nplaum, plasters, thiab cov khoom siv cement.
Pobzeb Adhesives thiab Grouts: Nruab nrab mus rau siab viscosity HPMC (2% tov nrog 4,000-20,000 cps) txhim kho kev ua haujlwm, dej tuav, thiab adhesion zog.
Cement Plasters: Nruab nrab viscosity HPMC (1% tov nrog 400-4,000 cps) txhim khu cov dej tuav thiab ua haujlwm, tiv thaiv kev tawg thiab txhim kho qhov ua tiav.
Kev ntsuas viscosity thiab cov qauv
Viscosity ntawm HPMC feem ntau ntsuas siv lub viscometer, thiab cov txiaj ntsig tau qhia hauv centipoise (cps). Cov txheej txheem txheem xws li Brookfield viscometry lossis capillary viscometry yog ua haujlwm nyob ntawm qhov viscosity ntau. Kev xaiv ntawm qib tsim nyog ntawm HPMC yog coj los ntawm cov kev qhia tshwj xeeb muab los ntawm cov tuam txhab, uas suav nrog cov ncauj lus kom ntxaws viscosity.
Kev xav txog tswv yim
Thaum xaiv HPMC rau ib daim ntawv thov tshwj xeeb, ntau qhov kev txiav txim siab yuav tsum raug coj mus rau hauv tus account:
Kev npaj daws teeb meem: hydration thiab soluble kom zoo yog qhov tseem ceeb rau kev ua tiav qhov xav tau viscosity. Maj mam ntxiv rau cov dej nrog kev nplawm tas li pab tiv thaiv cov pob tsim.
Compatibility: Kev sib raug zoo ntawm HPMC nrog rau lwm cov khoom xyaw tsim nyog yuav tsum tau kuaj xyuas kom ruaj khov thiab ua tau zoo.
Cia Tej yam kev mob: viscosity tuaj yeem cuam tshuam los ntawm kev cia khoom xws li kub thiab av noo. Kev khaws cia hauv qhov chaw txias, qhuav yog qhov tseem ceeb los tswj hwm HPMC kom zoo.
Qhov tsim nyog viscosity ntawm Hydroxypropyl Methyl Cellulose (HPMC) nws txawv nyob ntawm daim ntawv thov, xws li los ntawm tsawg viscosity rau emulsification thiab stabilization nyob rau hauv cov khoom noj khoom haus mus rau siab viscosity rau kev tswj tshuaj tso tawm nyob rau hauv pharmaceuticals. Kev nkag siab txog cov kev cai tshwj xeeb ntawm txhua qhov kev lag luam thiab daim ntawv thov yog qhov tseem ceeb rau kev xaiv cov qib zoo ntawm HPMC, kom ntseeg tau tias kev ua tau zoo thiab kev ua haujlwm zoo. Los ntawm kev txiav txim siab txog yam xws li qhov hnyav molecular, concentration, kub, thiab pH, cov tuam ntxhab tuaj yeem tsim cov kev daws teeb meem HPMC kom tau raws li cov kev xav tau ntawm cov qauv.
Post lub sij hawm: May-22-2024