Hydroxypropyl methylcellulose (HPMC)yog ntau yam polymer siv hauv kev lag luam xws li tshuaj, kev tsim kho, tshuaj pleev ib ce, zaub mov, thiab kev saib xyuas tus kheej. Lub viscosity ntawm HPMC ua lub luag haujlwm tseem ceeb hauv kev txiav txim siab nws qhov tsim nyog rau ntau yam kev siv. Lub viscosity yog cuam tshuam los ntawm qhov hnyav molecular, qib kev hloov pauv, thiab concentration. Kev nkag siab txog cov qib viscosity tsim nyog yog qhov tseem ceeb rau kev xaiv HPMC txoj cai rau cov kev xav tau tshwj xeeb.
Kev ntsuas viscosity
Lub viscosity ntawm AnxinCel®HPMC feem ntau yog ntsuas hauv cov tshuaj aqueous siv lub rotational lossis capillary viscometer. Tus qauv ntsuas kub yog 20 ° C, thiab cov viscosity qhia nyob rau hauv millipascal-seconds (mPa·s lossis cP, centipoise). Ntau qib ntawm HPMC muaj cov viscosities sib txawv nyob ntawm lawv qhov kev thov.
Viscosity Qib thiab lawv daim ntawv thov
Cov lus hauv qab no qhia txog cov qib viscosity ntau ntawm HPMC thiab lawv cov ntawv thov sib xws:
| Qib Viscosity (mPa·s) | Hom Cuam Tshuam (%) | Daim ntawv thov |
| 5-100 | 2 | Qhov muag tee, khoom noj khoom haus additives, suspensions |
| 100-400 | 2 | Tablet coatings, binders, adhesives |
| 400-1,500 Nws | 2 | Emulsifiers, lubricants, tshuaj xa cov tshuab |
| 1,500-4,000 | 2 | Thickening agents, khoom tu tus kheej |
| 4,000-15,000 | 2 | Kev tsim kho (cov nplais nplaum, cov khoom siv cement) |
| 15,000 – 75,000 | 2 | Tswj-tso tshuaj formulations, kev tsim grouts |
| 75,000 – 200,000 | 2 | High-viscosity nplaum, cement reinforcement |
Cov yam ntxwv cuam tshuam rau viscosity
Ntau yam cuam tshuam rau viscosity ntawm HPMC:
Molecular Luj:Kev hnyav dua molecular ua rau kom muaj viscosity.
Degree ntawm Kev Hloov:Qhov piv ntawm hydroxypropyl thiab methyl pawg cuam tshuam rau solubility thiab viscosity.
Kev daws Concentration:Cov concentration ntau dua ua rau muaj viscosity ntau dua.
Kub:Viscosity txo nrog nce kub.
pH rhiab heev:HPMC cov kev daws teeb meem ruaj khov nyob rau hauv pH ntau ntawm 3-11 tab sis tuaj yeem degrade sab nraum qhov no.
Shear Rate:HPMC nthuav tawm cov khoom tsis yog-Newtonian ntws, lub ntsiab lus viscosity txo qis hauv kev ntxhov siab.
Application-Specific Considerations
Pharmaceuticals:HPMC yog siv nyob rau hauv cov tshuaj formulations rau tswj kev tso tawm thiab raws li ib tug binder nyob rau hauv cov ntsiav tshuaj. Cov qib viscosity qis (100–400 mPa·s) yog qhov nyiam rau cov txheej txheem, thaum cov qib siab dua (15,000+ mPa·s) yog siv rau cov qauv tsim tawm.
Kev tsim kho:AnxinCel®HPMC ua tus neeg saib xyuas dej thiab cov nplaum hauv cov khoom siv cement. Cov qib viscosity siab (siab dua 4,000 mPa·s) yog qhov zoo tshaj plaws rau kev txhim kho kev ua haujlwm thiab kev sib khi lub zog.
Tshuaj pleev ib ce thiab kho tus kheej:Hauv cov tshuaj zawv plaub hau, tshuaj pleev ib ce, thiab tshuaj pleev, HPMC ua haujlwm ua cov thickener thiab stabilizer. Qib nruab nrab viscosity (400–1,500 mPa·s) muab qhov sib npaug zoo ntawm kev ntxhib los mos thiab cov khoom ntws.
Kev lag luam zaub mov:Raws li cov khoom noj ntxiv (E464), HPMC txhim kho kev ntxhib los mos, ruaj khov, thiab khaws cov dej noo. Cov qib viscosity qis dua (5–100 mPa·s) ua kom muaj kev sib cais kom zoo yam tsis muaj thickening ntau.
Kev xaiv ntawmHPMCQib viscosity nyob ntawm daim ntawv thov, nrog cov qib viscosity qis dua tsim nyog rau cov kev daws teeb meem uas yuav tsum tau qis qis thiab qib viscosity siab dua siv hauv cov qauv uas yuav tsum muaj cov nplaum nplaum thiab ruaj khov. Kev tswj kom zoo viscosity ua kom muaj txiaj ntsig zoo hauv kev lag luam tshuaj, kev tsim kho, zaub mov, thiab tshuaj pleev ib ce kev lag luam. Kev nkag siab txog cov xwm txheej cuam tshuam rau viscosity pab txhawm rau txhim kho kev siv HPMC rau ntau daim ntawv thov kev lag luam.
Lub sij hawm xa tuaj: Feb-11-2025