Hydroxypropyl methylcellulose (HPMC)fim din yana da kyakkyawan aiki, amma saboda HPMC shine gel na thermal, danko a ƙananan zafin jiki yana da ƙananan ƙananan, wanda ba shi da amfani ga sutura (ko dipping) da bushewa a ƙananan zafin jiki don shirya fim mai cin abinci, wanda ya haifar da rashin aikin aiki; Bugu da kari, tsadarsa yana iyakance aikace-aikacen sa. Hydroxypropyl sitaci (HPS) ne mai low-cost sanyi gel, ta Bugu da kari iya kara danko na HPMC a low zafin jiki, inganta aiki yi na HPMC, da kuma rage samar da kudin, kara, guda hydrophilicity , glucose raka'a da hydroxypropyl kungiyoyin duk taimaka wajen inganta karfinsu na wadannan biyu polymers. Sabili da haka, an shirya tsarin haɗin gel mai zafi mai zafi ta hanyar haɗakarwa HPS da HPMC, kuma tasirin zafin jiki akan tsarin gel na HPMC/HPS zafi-sanyi gel gauraya tsarin an yi nazari akai-akai ta hanyar amfani da rheometer da ƙananan hanyoyin watsawa na X-ray. , Haɗe tare da tasirin yanayin maganin zafi a kan ƙananan ƙwayoyin cuta da kaddarorin tsarin membrane, sa'an nan kuma ya gina dangantaka tsakanin tsarin gel na tsarin haɗuwa-membrane-tsari-membrane Properties a karkashin yanayin zafi zafi.
Sakamakon ya nuna cewa a babban zafin jiki, gel tare da mafi girmaHPMCabun ciki yana da mafi girma modules kuma mafi mahimmancin hali mai ƙarfi, tsarin irin na kansa na masu rarraba gel ya fi girma, kuma girman tarin gel ya fi girma; a ƙananan zafin jiki, abun ciki na HPS Samfuran gel mafi girma suna da modules mafi girma, ƙarin fitattun halaye masu ƙarfi, da tsari mai kama da kai na masu rarraba gel. Ga samfuran da ke da rabon haɗakarwa iri ɗaya, ma'anar ma'auni da ƙaƙƙarfan halaye masu ƙarfi da ƙaƙƙarfan tsari iri ɗaya na gels ɗin da HPMC ke mamayewa a babban zafin jiki sun fi waɗanda HPS ke mamayewa a ƙananan zafin jiki. Yanayin bushewa zai iya rinjayar tsarin gel na tsarin kafin bushewa, sa'an nan kuma ya shafi tsarin crystalline da tsarin amorphous na fim din, kuma a ƙarshe yana da tasiri mai mahimmanci a kan kayan aikin injiniya na fim din, wanda ya haifar da ƙarfin ƙugiya da modules na fim ɗin ya bushe a babban zafin jiki. Ya fi bushewa a ƙananan zafin jiki. Adadin sanyaya ba shi da wani tasiri mai mahimmanci akan tsarin crystalline na tsarin, amma yana da tasiri akan girman microdomain mai kama da jikin fim. A cikin wannan tsarin, nauyin nau'in tsari mai kama da kai na fim zai iya rinjayar kayan aikin injiniya na fim din. Yin aiki yana da babban tasiri.
Dangane da shirye-shiryen ƙwayar ƙwayar cuta, binciken ya gano cewa yin amfani da maganin aidin don zaɓin rini da haɗewar membrane na HPMC/HPS ya kafa wata sabuwar hanya don a fili lura da rarraba lokaci da canjin lokaci na tsarin gauraye a ƙarƙashin na'urar hangen nesa. Hanyar, wanda ke da mahimmancin jagora don nazarin rarraba lokaci na tsarin gauraya tushen sitaci. Yin amfani da wannan sabon hanyar bincike, haɗe tare da infrared spectroscopy, scanning microscopy electron microscopy da extensometer, an yi nazari da nazarin lokaci, daidaitawa da kayan aikin injiniya na tsarin da kuma nazarin, kuma an gina daidaituwa, canjin lokaci da bayyanar fim. dangantaka tsakanin aiki. Sakamakon lura da na'urar microscope ya nuna cewa tsarin yana jujjuya canjin lokaci lokacin da rabon HPS ya kasance 50%, kuma yanayin haɗuwa tsakanin tsaka-tsaki ya kasance a cikin fim ɗin, yana nuna cewa tsarin yana da takamaiman matakin dacewa; infrared, bincike na thermogravimetric da sakamakon SEM sun kara tabbatar da haɗuwa. Tsarin yana da takamaiman matakin dacewa. Yanayin fim ɗin da aka haɗe yana canzawa lokacin da abun ciki na HPS ya kasance 50%. Lokacin daHPSabun ciki yana da girma fiye da 50%, kusurwar lambar sadarwa na samfurin da aka haɗe ya bambanta daga madaidaiciyar layin da ke haɗa kusurwoyi na samfurori masu tsabta, kuma lokacin da ya kasa da 50%, ya karkata daga wannan madaidaiciyar layi. , wanda akasari ke haifar da canjin lokaci.
Lokacin aikawa: Afrilu-25-2024